Results 111 to 120 of about 1,233,997 (314)

Natural Product Communications: Editorial [PDF]

, 2009
University of Perugia Department of Drug Chemistry and Technology (Organic Chemistry Section), Via del Liceo 1, 06123 PerugiaUniversidade Estadual Paulista (UNESP) Chemistry Institut of Araraquara, Caixa Postal 335, 14801-970 AraraquaraUniversidade ...
Curini, Massimo, Vilegas, Wagner [UNESP]
core  

GC-MS analysis and antimicrobial activity of essential oil of Stachys cretica subsp. smyrnaea [PDF]

, 2009
PubMed ID: 19370886The essential oil from the aerial parts of Stachys cretica L. subsp. smyrnaea Rech. fil. (Lamiaceae), endemic to Turkey, was investigated by using GC and GC-MS.
Öztürk, Mehmet, Duru, M.E., Kolak, U., Mahliçli, M., Ulubelen, A., Aydoğmuş-Öztürk, F., Harmandar, M.   +6 more
core   +1 more source

The Aspergillus fumigatus cell wall integrity signalling pathway: drug target, compensatory pathways and virulence

Frontiers in Microbiology, 2015
Aspergillus fumigatus is the most important airborne fungal pathogen, causing severe infections with invasive growth in immunocompromised patients. The fungal cell wall prevents the cell from lysing and protects the fungus against environmental stress ...
Vito eValiante, Juliane eMacheleidt, Martin eFöge, Axel A Brakhage   +3 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Elucidation of the protective effect of schisandrin C originating from Schisandra chinensis (Turcz.) Baill. against indomethacin-induced intestinal injury by combining network pharmacology, molecular docking, and experimental validation

Applied Biological Chemistry
Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs), especially indomethacin, has severe adverse effects on the gastrointestinal system. Schisandra chinensis (Turcz.) Baill., an herbal medicine used to treat several gastrointestinal diseases ...
Son Hung Tran, Uyen Tran Tu Nguyen, Mi Ri Kim, Hee Ju Lee, Esther Youn, Won Young Bae, Suk Woo Kang, Won Kyu Kim, Ki Young Choi, Keunwan Park, Kyungsu Kang   +10 more
doaj   +1 more source

Antimicrobial Natural Products

Antibiotics, 2022
Infectious diseases, resulting from microbial pathogens, are one of the major causes of morbidity and mortality worldwide [...]
openaire   +3 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Isolation of Lactic Acid Bacteria with Cholesterol-Lowering Activity from Digestive Tracts of Indonesian Native Chickens

Media Peternakan, 2017
The aim of the study was to identify the cholesterol-lowering activity of indigenous lactic acid bacteria isolated from the small intestine, cecum, and colon of Indonesian native chickens and evaluated for bile salt hydrolase (BSH) activity in vitro by ...
H. Julendra, Ade Erma Suryani, Lusty Istiqomah, Ema Damayanti, Muslih Anwar, Naditya Fitriani   +5 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source