Results 81 to 90 of about 1,233,997 (314)

Anticancer agents from diverse natural sources [PDF]

open access: yes, 2014
Cancer is one of the major causes of death and the number of new cases, as well as the number of individuals living with cancer, is expanding continuously.
Riley, Darren Lyall   +4 more
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Natural-Product-Tailored Polyurethane: Size-Dictated Construction of Polypseudorotaxanes with Cyclodextrin–Triterpenoid Pairs [PDF]

open access: yes, 2018
Cyclodextrin (CD)-based polyrotaxanes (PRs) and polypseudorotaxanes (PPRs) have attracted considerable attention due to their unique topological structures and functions. However, limited by the simple chemical structures and the single functionalization
Chihui Zheng   +11 more
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Natural product growth inhibitors of Mycobacterium tuberculosis [PDF]

open access: yes, 2007
Covering: 2003–2005.https://www.ncbi.nlm.nih.gov/pubmed ...
Copp, Brent, Pearce, Allison
core   +1 more source

The spatial organization of sphingofungin biosynthesis in Aspergillus fumigatus and its cross-interaction with sphingolipid metabolism

open access: yesmBio
Sphingofungins are sphinganine analog mycotoxins acting as inhibitors of serine palmitoyl transferases, enzymes responsible for the first step in the sphingolipid biosynthesis.
Katarina Jojić   +9 more
doaj   +1 more source

Aporphine Alkaloids from the Chinese Tree

open access: yesNatural Product Communications, 2007
Three new oxygenated noraporphine alkaloids were isolated from the bark of the Chinese tree Neolitsea aurata var. paraciculata. The new compounds, (+)-11-methoxynorcassythicine, (+)-11-methoxynorneolitsine, (+)-11-methoxynorboldine, were isolated along ...
Malcolm S. Buchanan   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

An Infinite Natural Product [PDF]

open access: yesAnnales Mathematicae Silesianae, 2018
Abstract We study a countably infinite iteration of the natural product between ordinals.We present an “effective” way to compute this countable natural product; in the non trivial cases the result depends only on the natural sum of the degrees of the factors, where the degree of a nonzero ordinal is the largest exponent in its Cantor ...
openaire   +4 more sources

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