Results 111 to 120 of about 4,422,072 (371)
Nephrotoxicity of Natural Products [PDF]
<b><i>Background:</i></b> The manufacture and sale of natural products constitute a multi-billion dollar industry. Nearly a third of the American population admit to using some form of complementary or alternative medicine, with many using them in addition to prescription medications.
Mary Nauffal, Steven Gabardi
openaire +3 more sources
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa+13 more
wiley +1 more source
On the tensor product construction for q-differential algebras [PDF]
We show that for $q\not=-1$ the q-graded tensor product fails to preserve the q-differential structure of the product algebra and therefore there is no natural tensor product construction for q-differential algebras.
arxiv
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu+7 more
wiley +1 more source
On the Hochschild homology of open Frobenius algebras [PDF]
We prove that the shifted Hochschild chain complex $C\_*(A,A)[m]$ of a symmetric open Frobenius algebra $A$ of degree $m$ has a natural homotopy coBV-algebra structure.
Abbaspour, Hossein
core +2 more sources
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar+4 more
wiley +1 more source
Density of polynomials in classes of functions on products of planar domains [PDF]
We give sufficient conditions on planar domains for polynomials to be dense in the algebras A and A-infinity of the product of these domains, endowed with their natural topologies. We also characterize the uniform limits, with respect to the chordal metric, of polynomials on the product of the closures of these domains.
arxiv
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti+8 more
wiley +1 more source
Multiple sclerosis clinical decision support system based on projection to reference datasets
Abstract Objective Multiple sclerosis (MS) is a multifactorial disease with increasingly complicated management. Our objective is to use on‐demand computational power to address the challenges of dynamically managing MS. Methods A phase 3 clinical trial data (NCT00906399) were used to contextualize the medication efficacy of peg‐interferon beta‐1a vs ...
Chadia Ed‐driouch+13 more
wiley +1 more source
Sepsis is a clinical syndrome that can be caused by bacteria or fungi. Early knowledge on the nature of the causative agent is a prerequisite for targeted anti-microbial therapy.
Andreas eDix+5 more
doaj +1 more source