Results 111 to 120 of about 12,812,869 (370)

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Hecke operators on Hilbert-Siegel modular forms

open access: yes, 2007
We define Hilbert-Siegel modular forms and Hecke "operators" acting on them. As with Hilbert modular forms, these linear transformations are not linear operators until we consider a direct product of spaces of modular forms (with varying groups), modulo ...
Caulk, Suzanne, Walling, Lynne H.
core   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Natural Products and Cancer

open access: yesNutrients, 2023
Natural and dietary compounds are known to offer protection and affect the pathogeneses of numerous chronic diseases [...]
openaire   +2 more sources

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

Lagrangian Symmetries of Chern-Simons Theories

open access: yes, 1998
This paper analyses the Noether symmetries and the corresponding conservation laws for Chern-Simons Lagrangians in dimension $d=3$. In particular, we find an expression for the superpotential of Chern-Simons gravity.
Anderson I M   +15 more
core   +3 more sources

Capturing Biological Activity in Natural Product Fragments by Chemical Synthesis

open access: yesAngewandte Chemie, 2016
Natural products have had an immense influence on science and have directly led to the introduction of many drugs. Organic chemistry, and its unique ability to tailor natural products through synthesis, provides an extraordinary approach to unlock the ...
E. A. Crane, K. Gademann
semanticscholar   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Elucidation of the protective effect of schisandrin C originating from Schisandra chinensis (Turcz.) Baill. against indomethacin-induced intestinal injury by combining network pharmacology, molecular docking, and experimental validation

open access: yesApplied Biological Chemistry
Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs), especially indomethacin, has severe adverse effects on the gastrointestinal system. Schisandra chinensis (Turcz.) Baill., an herbal medicine used to treat several gastrointestinal diseases ...
Son Hung Tran   +10 more
doaj   +1 more source

On the automorphisms of a graph product of abelian groups

open access: yes, 2007
We study the automorphisms of a graph product of finitely-generated abelian groups W. More precisely, we study a natural subgroup Aut* W of Aut W, with Aut* W = Aut W whenever vertex groups are finite and in a number of other cases.
Gutierrez, Mauricio   +2 more
core   +2 more sources

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