Results 51 to 60 of about 12,950,355 (371)

Translation to Bundle Operators [PDF]

open access: yes, 2007
We give explicit formulas for conformally invariant operators with leading term an $m$-th power of Laplacian on the product of spheres with the natural pseudo-Riemannian product metric for all $m$.Comment: This is a contribution to the Proceedings of the
Branson, Thomas P., Hong, Doojin
core   +5 more sources

Scalemic natural products

open access: yesNatural Product Reports, 2023
In natural products, a low optical purity is not generally associated with a sloppy enzymatic activity, but rather with the co-expression of antipodal enzymes/directing proteins or, alternatively, with erosion by enzymatic or spontaneous reactions.
Mazzotta, Sarah   +5 more
openaire   +2 more sources

Harnessing the Anti-Cancer Natural Product Nimbolide for Targeted Protein Degradation

open access: yesbioRxiv, 2018
Nimbolide, a terpenoid natural product derived from the Neem tree, impairs cancer pathogenicity; however, the direct targets and mechanisms by which nimbolide exerts its effects are poorly understood. Here, we used activity-based protein profiling (ABPP)
Jessica N. Spradlin   +17 more
semanticscholar   +1 more source

Intramolecular Imino Diels-Alder Reaction: Progress toward the Synthesis of Uncialamycin [PDF]

open access: yes, 2009
We herein described an intramolecular imino Diels-Alder reaction promoted with BF3.OEt2/DDQ affording substituted quinolines. Using this procedure, we prepared the chiral quitioline moiety of the uncialamycin, a new enediyne natural ...
Desrat, S, van de Weghe, P
core   +1 more source

Natural products in cosmetics

open access: yesNatural Products and Bioprospecting, 2022
AbstractThe global cosmetics market reached US$500 billion in 2017 and is expected to exceed US$800 billion by 2023, at around a 7% annual growth rate. The cosmetics industry is emerging as one of the fastest-growing industries of the past decade. Data shows that the Chinese cosmetics market was US$60 billion in 2021.
openaire   +3 more sources

Lactic Acid Bacteria Isolates and the Microbiome of Cincalok, Tempoyak, and Mandai: A Traditional Fermented Food from Kalimantan Island, Indonesia

open access: yesInternational Journal of Food Science
Indonesia has abundant traditional fermented food with various lactic acid bacteria (LAB), which can be developed into probiotics for pharmaceutical and functional food and feed products.
Retno Murwani   +6 more
doaj   +1 more source

Diversity and biosynthetic potential of culturable microbes associated with toxic marine animals [PDF]

open access: yes, 2013
Tetrodotoxin (TTX) is a neurotoxin that has been reported from taxonomically diverse organisms across 14 different phyla. The biogenic origin of tetrodotoxin is still disputed, however, TTX biosynthesis by host-associated bacteria has been reported.
Chau, Rocky   +3 more
core   +4 more sources

Speciation Through the Lens of Population Dynamics: A Theoretical Primer on How Small and Large Populations Diverge

open access: yesPopulation Ecology, EarlyView.
Population size and dynamics fundamentally shape speciation by influencing genetic drift, founder events, and adaptive potential. Small populations may speciate rapidly due to stronger drift, whereas large populations harbor more genetic diversity, which can alter divergence trajectories. We highlight theoretical models that incorporate population size
Ryo Yamaguchi   +3 more
wiley   +1 more source

Discovery of 15-deoxynaphthomycins activating the antioxidant NRF2-ARE pathway from Streptomyces sp. N50 via genome mining, global regulator introduction, and molecular networking

open access: yesMicrobial Cell Factories
Genome mining is a promising avenue for expanding the repertoire of microbial natural products, which are important for drug development. This approach involves predicting genetically encoded small molecules by examining bacterial genomes via accumulated
Min-Seon Kim   +5 more
doaj   +1 more source

Microbial communication leading to the activation of silent fungal secondary metabolite gene clusters

open access: yesFrontiers in Microbiology, 2015
Microorganisms form diverse multispecies communities in various ecosystems. The high abundance of fungal and bacterial species in these consortia results in specific communication between the microorganisms.
Tina eNetzker   +13 more
doaj   +1 more source

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