Results 11 to 20 of about 1,046,985 (303)

Click Chemistry in Natural Product Modification [PDF]

Frontiers in Chemistry, 2021
Click chemistry is perhaps the most powerful synthetic toolbox that can efficiently access the molecular diversity and unique functions of complex natural products up to now.
Xiang Zhang, Shuning Zhang, Songfeng Zhao, Xuan Wang, Bo Liu, Hongtao Xu   +5 more
doaj   +3 more sources

Natural Product Chemistry and Biological Research. [PDF]

Int J Mol Sci
Natural products are substances found in nature that have not been significantly modified by humans [...]
Les F, Valero MS, Arruebo MP.
europepmc   +3 more sources

Antibiofilm and antibacterial activities of lupinifolin in combination with protein synthesis inhibitors against methicillin-resistant Staphylococcus aureus [PDF]

Journal of HerbMed Pharmacology, 2023
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA)-derived biofilm formation is a crucial virulence factor, which essentially contributes to therapeutic challenges.
Parichart Kwaengmuang, Koravich Chaiyawong, Todsapon Warong, Sakulrat Rattanakiat, Pawitra Pulbutr   +4 more
doaj   +1 more source

The crystal structure of 13-(pyrazole-1-yl-4-carbonitrile)-matrine, C19H25N5O

Zeitschrift für Kristallographie - New Crystal Structures, 2021
C19H25N5O, monoclinic, P21 (no. 4), a = 16.0600(2) Å, b = 5.3992(1) Å, c = 19.8514(2) Å, β = 94.260(1)°, V = 1716.58(4) Å3, Z = 4, Rgt (F) = 0.0350, wRref(F2) = 0.0908, T = 100.00(10) K.
Li Jun-Jie, Dong Fang-Yun, Zou Qi-Wen, Feng Yin, Yang Yu-Tao, Su Kai-Xuan, Huang Yong-Fu, Jiang Xu-Hong, Cheng Xing-An   +8 more
doaj   +1 more source

A PRELIMINARY QUALITATIVE STUDY OF AN ALKALOID IN THE FRUIT OF TERONG BELANDA (Cyphomandra betacea, Cav)

Indonesian Journal of Chemistry, 2010
Preliminary studies on Terong Belanda (C. betacea ) have been carried out in this investigation with an aim to examine the presence of an alkaloid in the fruit of Terong Belanda.
Fredryk Mandey, Mikael Dominggus, Tjodi Harlim   +2 more
doaj   +1 more source

Click-based synthesis and proteomic profiling of lipstatin analogues [PDF]

, 2010
Using click chemistry to enable both structural diversity and proteome profiling within a natural product derived library, two out of nineteen lipstatin analogues showed similar activity to Orlistat against fatty acid synthase (FAS), but with an improved
Adam, Brik, Browne, Carpita, Carvalho, Cheng, Evans, Garcia-Fandino, Guerciolini, Kai Liu, Kalesh, Kalesh, Keck, Knowles, Knowles, Kridel, Kridel, Little, Little, Ma, Markus R. Wenk, Martin J. Lear, Menendez, Menendez, Menendez, Mori, Morten Meldal, Mun H. Ngai, Pemble, Peng-Yu Yang, Pommier, Richardson, Shao Q. Yao, Sletten, Srinivasan, Srinivasan, Uttamchandani, Yang, Yuan Shen   +38 more
core   +1 more source

Perylenequinones from an endophytic Alternaria sp. of Pinus ponderosa

Heliyon, 2018
The differential solvent extraction and further purification of fractions of endophytic Alternaria sp. isolated from Pinus ponderosa led to the isolation of further two perylenequinone compounds as 3,6,6a,9,10-pentahydroxy-7,8-epoxy-4-oxo-4,5,6,6a,6b,7,8,
Mudasir A. Tantry, Ahmed S. Idris, John S. Williamson, Tasfi Shafi, Jehangir S. Dar, Tauseef A. Malik, Bashir A. Ganai, Abdul S. Shawl   +7 more
doaj   +1 more source

Identification of a new p53/MDM2 inhibitor motif inspired by studies of chlorofusin [PDF]

, 2015
Previous studies on the natural product chlorofusin have shown that the full peptide and azaphilone structure are required for inhibition of the interaction between MDM2 and p53.
Clark, Clark, Clark, Desai, Duncan, Ewan Raffel, Howell, Jordann C. Ramoutar, Kerrie D. Turner, Knight, Kolb, Lee, Lesley A. Howell, Li, Malkinson, Marco M.D. Cominetti, Maria A. O’Connell, Mark Searcey, Mori, Qian, Qiu, Qiu, Sang, Sarah A. Goffin, Woon   +24 more
core   +1 more source

Isolation and characterization of starch from Limnophila aromatica

Heliyon, 2019
Starch is one of the digestible natural polymers found in vascular plants. This natural polymer is the primary source of polysaccharides to produce energy for humans.
Cynthia Wijaya, Quy Diem Do, Yi Hsu Ju, Shella Permatasari Santoso, Jindrayani Nyoo Putro, Livy Laysandra, Felycia Edi Soetaredjo, Suryadi Ismadji   +7 more
doaj   +1 more source

The stellar halo of the Galaxy [PDF]

, 2008
Stellar halos may hold some of the best preserved fossils of the formation history of galaxies. They are a natural product of the merging processes that probably take place during the assembly of a galaxy, and hence may well be the most ubiquitous ...
A Frebel, A Frebel, A Gould, A Gould, A Heger, A Helmi, A Helmi, A Helmi, A Helmi, A Helmi, A Helmi, A Helmi, A Helmi, A Helmi, A Helmi, A Klypin, A Klypin, A Koch, A McWilliam, A Moitinho, A Sarajedini, AA Kepley, AC Layden, AC Layden, AC Robin, AC Robin, AD Mackey, AJ Benson, AK Vivas, AK Vivas, Amina Helmi, AP Digby, AR Zentner, AS Font, AV Kravtsov, AV Kravtsov, AW McConnachie, B Chaboyer, B Chen, B Famaey, B Fuchs, B Letarte, B Moore, B Moore, B Paczynski, B Yanny, B Yanny, BMS Hansen, BW Carney, C Chiappini, C Flynn, C Sneden, C Travaglio, CB Brook, CB Brook, CJ Grillmair, CJ Grillmair, CJ Grillmair, CJ Grillmair, CS Frenk, D Carollo, D Geisler, D Lynden-Bell, D Martínez-Delgado, D Martínez-Delgado, D Martínez-Delgado, D Minniti, DI Casetti-Dinescu, DI Dinescu, DJ Lemon, DN Spergel, DR Law, E Bica, E Carretta, E Sirko, E Tolstoy, E Tolstoy, F De Angeli, F Hammer, F Matteucci, F Stoehr, FDA Hartwick, G Battaglia, G Battaglia, G Cescutti, G Gilmore, G Gilmore, G Gilmore, G Kauffmann, G Piotto, GM De Silva, GM Seabroke, GW Preston, H Baumgardt, H Shapley, H Umeda, HJ Newberg, HJ Newberg, HJ Newberg, HJ Rocha-Pinto, HL Morrison, HL Morrison, HL Morrison, II Ivans, J Binney, J Bland-Hawthorn, J Diemand, J Mould, J Peñarrubia, J Silk, J Sommer-Larsen, J Sommer-Larsen, J Tumlinson, JC Kapteyn, JC Wheeler, JD Simon, JF Navarro, JF Navarro, JG Cohen, JK Adelman-McCarthy, JN Bahcall, JP Fulbright, JS Bullock, JS Bullock, JS Bullock, JS Kalirai, K Bekki, KA Venn, KC Freeman, KM Ashman, KU Ratnatunga, KV Johnston, KV Johnston, KV Johnston, KV Johnston, L Clewley, L Clewley, L Gao, L Mayer, L Searle, LV Sales, M Arnould, M Bellazzini, M Chiba, M Chiba, M Chiba, M Fellhauer, M Juric, M Mateo, M Metz, M Mouhcine, M Mouhcine, M Mouhcine, M Odenkirchen, M Samland, M Schmidt, M Shetrone, M Shetrone, M Steinmetz, M Steinmetz, M Unavane, M-M Mac Low, MA Gómez-Flechoso, MAC Perryman, MC Smith, MG Abadi, MG Abadi, MH Siegel, MH Siegel, MI Wilkinson, ML Mateo, N Libeskind, NB Suntzeff, NC Hambly, NF Martin, NF Martin, NY Gnedin, OJ Eggen, P Côté, P François, P Harding, P Kroupa, PB Stetson, PB Stetson, PD Sackett, PE Nissen, PE Nissen, PJ Quinn, PS Barklem, R Cayrel, R Cayrel, R Ibata, R Ibata, R Ibata, R Ibata, R Schneider, RC Dohm-Palmer, RP Marel van der, RP Marel van der, RS Somerville, S Duffau, S Lucatello, S Phleps, S Piatek, S Salvadori, S Torres, S Zibetti, SC Chapman, SDM White, SDM White, SG Ryan, SR Majewski, SR Majewski, SR Majewski, SR Majewski, T Abel, TC Beers, TC Beers, TD Kinman, TD Kinman, TM Brown, V Belokurov, V Belokurov, V Belokurov, V Belokurov, V Belokurov, V Bromm, V Hill, V Springel, W Dehnen, WE Harris, X Kang, Y Momany, Y Momany, Y Xu, Y Xu, Y-W Lee, YS Li, YW Lee, Z Zheng, Ž Ivezić   +240 more
core   +3 more sources