Results 11 to 20 of about 1,189,605 (351)

A PRELIMINARY QUALITATIVE STUDY OF AN ALKALOID IN THE FRUIT OF TERONG BELANDA (Cyphomandra betacea, Cav)

Indonesian Journal of Chemistry, 2010
Preliminary studies on Terong Belanda (C. betacea ) have been carried out in this investigation with an aim to examine the presence of an alkaloid in the fruit of Terong Belanda.
Fredryk Mandey, Mikael Dominggus, Tjodi Harlim   +2 more
doaj   +1 more source

Click-based synthesis and proteomic profiling of lipstatin analogues [PDF]

, 2010
Using click chemistry to enable both structural diversity and proteome profiling within a natural product derived library, two out of nineteen lipstatin analogues showed similar activity to Orlistat against fatty acid synthase (FAS), but with an improved
Adam, Brik, Browne, Carpita, Carvalho, Cheng, Evans, Garcia-Fandino, Guerciolini, Kai Liu, Kalesh, Kalesh, Keck, Knowles, Knowles, Kridel, Kridel, Little, Little, Ma, Markus R. Wenk, Martin J. Lear, Menendez, Menendez, Menendez, Mori, Morten Meldal, Mun H. Ngai, Pemble, Peng-Yu Yang, Pommier, Richardson, Shao Q. Yao, Sletten, Srinivasan, Srinivasan, Uttamchandani, Yang, Yuan Shen   +38 more
core   +1 more source

Perylenequinones from an endophytic Alternaria sp. of Pinus ponderosa

Heliyon, 2018
The differential solvent extraction and further purification of fractions of endophytic Alternaria sp. isolated from Pinus ponderosa led to the isolation of further two perylenequinone compounds as 3,6,6a,9,10-pentahydroxy-7,8-epoxy-4-oxo-4,5,6,6a,6b,7,8,
Mudasir A. Tantry, Ahmed S. Idris, John S. Williamson, Tasfi Shafi, Jehangir S. Dar, Tauseef A. Malik, Bashir A. Ganai, Abdul S. Shawl   +7 more
doaj   +1 more source

Identification of a new p53/MDM2 inhibitor motif inspired by studies of chlorofusin [PDF]

, 2015
Previous studies on the natural product chlorofusin have shown that the full peptide and azaphilone structure are required for inhibition of the interaction between MDM2 and p53.
Clark, Clark, Clark, Desai, Duncan, Ewan Raffel, Howell, Jordann C. Ramoutar, Kerrie D. Turner, Knight, Kolb, Lee, Lesley A. Howell, Li, Malkinson, Marco M.D. Cominetti, Maria A. O’Connell, Mark Searcey, Mori, Qian, Qiu, Qiu, Sang, Sarah A. Goffin, Woon   +24 more
core   +1 more source

Isolation and characterization of starch from Limnophila aromatica

Heliyon, 2019
Starch is one of the digestible natural polymers found in vascular plants. This natural polymer is the primary source of polysaccharides to produce energy for humans.
Cynthia Wijaya, Quy Diem Do, Yi Hsu Ju, Shella Permatasari Santoso, Jindrayani Nyoo Putro, Livy Laysandra, Felycia Edi Soetaredjo, Suryadi Ismadji   +7 more
doaj   +1 more source

Collected mass spectrometry data on monoterpene indole alkaloids from natural product chemistry research

Scientific Data, 2019
This Data Descriptor announces the submission to public repositories of the monoterpene indole alkaloid database (MIADB), a cumulative collection of 172 tandem mass spectrometry (MS/MS) spectra from multiple research projects conducted in eight natural ...
Alexander E. Fox Ramos, P. Le Pogam, Charlotte Fox Alcover, Elvis Otogo N’Nang, Gaëla Cauchie, H. Hazni, K. Awang, Dimitri Bréard, A. Echavarren, M. Frédérich, T. Gaslonde, M. Girardot, R. Grougnet, M. Kirillova, M. Kritsanida, C. Lémus, Anne-Marie Le Ray, G. Lewin, M. Litaudon, L. Mambu, S. Michel, F. Miloserdov, Michael E Muratore, Pascal Richomme-Peniguel, F. Roussi, L. Evanno, E. Poupon, P. Champy, M. Beniddir   +28 more
semanticscholar   +1 more source

Functionalized Nitroimidazole Scaffold Construction and Their Pharmaceutical Applications: A 1950–2021 Comprehensive Overview

Pharmaceuticals, 2022
Nitroimidazole represents one of the most essential and unique scaffolds in drug discovery since its discovery in the 1950s. It was K. Maeda in Japan who reported in 1953 the first nitroimidazole as a natural product from Nocardia mesenterica with ...
Ria Gupta, Sumit Sharma, Rohit Singh, Ram A. Vishwakarma, Serge Mignani, Parvinder Pal Singh   +5 more
doaj   +1 more source

The stellar halo of the Galaxy [PDF]

, 2008
Stellar halos may hold some of the best preserved fossils of the formation history of galaxies. They are a natural product of the merging processes that probably take place during the assembly of a galaxy, and hence may well be the most ubiquitous ...
A Frebel, A Frebel, A Gould, A Gould, A Heger, A Helmi, A Helmi, A Helmi, A Helmi, A Helmi, A Helmi, A Helmi, A Helmi, A Helmi, A Helmi, A Klypin, A Klypin, A Koch, A McWilliam, A Moitinho, A Sarajedini, AA Kepley, AC Layden, AC Layden, AC Robin, AC Robin, AD Mackey, AJ Benson, AK Vivas, AK Vivas, Amina Helmi, AP Digby, AR Zentner, AS Font, AV Kravtsov, AV Kravtsov, AW McConnachie, B Chaboyer, B Chen, B Famaey, B Fuchs, B Letarte, B Moore, B Moore, B Paczynski, B Yanny, B Yanny, BMS Hansen, BW Carney, C Chiappini, C Flynn, C Sneden, C Travaglio, CB Brook, CB Brook, CJ Grillmair, CJ Grillmair, CJ Grillmair, CJ Grillmair, CS Frenk, D Carollo, D Geisler, D Lynden-Bell, D Martínez-Delgado, D Martínez-Delgado, D Martínez-Delgado, D Minniti, DI Casetti-Dinescu, DI Dinescu, DJ Lemon, DN Spergel, DR Law, E Bica, E Carretta, E Sirko, E Tolstoy, E Tolstoy, F De Angeli, F Hammer, F Matteucci, F Stoehr, FDA Hartwick, G Battaglia, G Battaglia, G Cescutti, G Gilmore, G Gilmore, G Gilmore, G Kauffmann, G Piotto, GM De Silva, GM Seabroke, GW Preston, H Baumgardt, H Shapley, H Umeda, HJ Newberg, HJ Newberg, HJ Newberg, HJ Rocha-Pinto, HL Morrison, HL Morrison, HL Morrison, II Ivans, J Binney, J Bland-Hawthorn, J Diemand, J Mould, J Peñarrubia, J Silk, J Sommer-Larsen, J Sommer-Larsen, J Tumlinson, JC Kapteyn, JC Wheeler, JD Simon, JF Navarro, JF Navarro, JG Cohen, JK Adelman-McCarthy, JN Bahcall, JP Fulbright, JS Bullock, JS Bullock, JS Bullock, JS Kalirai, K Bekki, KA Venn, KC Freeman, KM Ashman, KU Ratnatunga, KV Johnston, KV Johnston, KV Johnston, KV Johnston, L Clewley, L Clewley, L Gao, L Mayer, L Searle, LV Sales, M Arnould, M Bellazzini, M Chiba, M Chiba, M Chiba, M Fellhauer, M Juric, M Mateo, M Metz, M Mouhcine, M Mouhcine, M Mouhcine, M Odenkirchen, M Samland, M Schmidt, M Shetrone, M Shetrone, M Steinmetz, M Steinmetz, M Unavane, M-M Mac Low, MA Gómez-Flechoso, MAC Perryman, MC Smith, MG Abadi, MG Abadi, MH Siegel, MH Siegel, MI Wilkinson, ML Mateo, N Libeskind, NB Suntzeff, NC Hambly, NF Martin, NF Martin, NY Gnedin, OJ Eggen, P Côté, P François, P Harding, P Kroupa, PB Stetson, PB Stetson, PD Sackett, PE Nissen, PE Nissen, PJ Quinn, PS Barklem, R Cayrel, R Cayrel, R Ibata, R Ibata, R Ibata, R Ibata, R Schneider, RC Dohm-Palmer, RP Marel van der, RP Marel van der, RS Somerville, S Duffau, S Lucatello, S Phleps, S Piatek, S Salvadori, S Torres, S Zibetti, SC Chapman, SDM White, SDM White, SG Ryan, SR Majewski, SR Majewski, SR Majewski, SR Majewski, T Abel, TC Beers, TC Beers, TD Kinman, TD Kinman, TM Brown, V Belokurov, V Belokurov, V Belokurov, V Belokurov, V Belokurov, V Bromm, V Hill, V Springel, W Dehnen, WE Harris, X Kang, Y Momany, Y Momany, Y Xu, Y Xu, Y-W Lee, YS Li, YW Lee, Z Zheng, Ž Ivezić   +240 more
core   +3 more sources

Furan-site transformations of obacunone as potent insecticidal agents

Heliyon, 2018
Furan ring is a key pharmacophore for insecticidal activity of limoninoids. To develop natural-product-based insecticidal agents, a series of furan-site transformations (2, 3 and 3a–j) of obacunone were synthesized by selective bromination and following ...
Ping Xiang, Qing-Hao Cao, Qing-Miao Dong, Xiao-Jun Yang, Jiang-Jiang Tang, Hongjin Bai   +5 more
doaj   +1 more source

Enantiomeric Mixtures in Natural Product Chemistry: Separation and Absolute Configuration Assignment

Molecules, 2018
Chiral natural product molecules are generally assumed to be biosynthesized in an enantiomerically pure or enriched fashion. Nevertheless, a significant amount of racemates or enantiomerically enriched mixtures has been reported from natural sources ...
Andrea N L Batista, Fernando M Dos Santos, J. Batista, Q. Cass   +3 more
semanticscholar   +1 more source