Results 11 to 20 of about 1,020,429 (254)

Natural product chemistry of gorgonian corals of genus Junceella--part II. [PDF]

open access: goldMar Drugs, 2011
Wu YC   +12 more
europepmc   +3 more sources

Isolation and characterization of starch from Limnophila aromatica

open access: yesHeliyon, 2019
Starch is one of the digestible natural polymers found in vascular plants. This natural polymer is the primary source of polysaccharides to produce energy for humans.
Cynthia Wijaya   +7 more
doaj   +1 more source

Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine

open access: yesNature Communications, 2022
The G-quadruplex formed in KRAS oncogene promoter (KRAS-G4) is a transcriptional modulator and amenable to small molecule targeting. Herein, the authors report the NMR solution structures of a bulge-containing KRAS-G4 that bound to two small molecules ...
Kai-Bo Wang   +10 more
doaj   +1 more source

Transcription activator-like effectors from endosymbiotic bacteria control the reproduction of their fungal host

open access: yesmBio, 2023
The phytopathogenic fungus Rhizopus microsporus harbors a bacterial endosymbiont (Mycetohabitans rhizoxinica) that produces a crucial virulence factor responsible for the characteristic symptoms of rice seedling blight.
Ingrid Richter   +7 more
doaj   +1 more source

Identification of a new p53/MDM2 inhibitor motif inspired by studies of chlorofusin [PDF]

open access: yes, 2015
Previous studies on the natural product chlorofusin have shown that the full peptide and azaphilone structure are required for inhibition of the interaction between MDM2 and p53.
Clark   +24 more
core   +1 more source

Furan-site transformations of obacunone as potent insecticidal agents

open access: yesHeliyon, 2018
Furan ring is a key pharmacophore for insecticidal activity of limoninoids. To develop natural-product-based insecticidal agents, a series of furan-site transformations (2, 3 and 3a–j) of obacunone were synthesized by selective bromination and following ...
Ping Xiang   +5 more
doaj   +1 more source

Molecular docking studies of Triphala with catalytic portion of HMG-CoA reductase enzyme [PDF]

open access: yesJournal of HerbMed Pharmacology, 2023
Introduction: Triphala, consisting of three fruits, Phyllanthus emblica L. (Phyllanthaceae), Terminalia bellirica (Gaertn.) Roxb. (Combretaceae), and T.
Prasoborn Rinthong   +2 more
doaj   +1 more source

The stellar halo of the Galaxy [PDF]

open access: yes, 2008
Stellar halos may hold some of the best preserved fossils of the formation history of galaxies. They are a natural product of the merging processes that probably take place during the assembly of a galaxy, and hence may well be the most ubiquitous ...
A Frebel   +240 more
core   +3 more sources

Facilitating biomimetic syntheses of borrerine derived alkaloids by means of flow-chemical methods [PDF]

open access: yes, 2015
Flow chemistry is widely used nowadays in synthetic chemistry and has increasingly been applied to complex natural product synthesis. However, to date flow chemistry has not found a place in the area of biomimetic synthesis.
Kamptmann, SB, Ley, SV
core   +1 more source

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