Results 11 to 20 of about 979,824 (352)
The phytopathogenic fungus Rhizopus microsporus harbors a bacterial endosymbiont (Mycetohabitans rhizoxinica) that produces a crucial virulence factor responsible for the characteristic symptoms of rice seedling blight.
Ingrid Richter+7 more
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Preliminary studies on Terong Belanda (C. betacea ) have been carried out in this investigation with an aim to examine the presence of an alkaloid in the fruit of Terong Belanda.
Fredryk Mandey+2 more
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The G-quadruplex formed in KRAS oncogene promoter (KRAS-G4) is a transcriptional modulator and amenable to small molecule targeting. Herein, the authors report the NMR solution structures of a bulge-containing KRAS-G4 that bound to two small molecules ...
Kai-Bo Wang+10 more
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Nitroimidazole represents one of the most essential and unique scaffolds in drug discovery since its discovery in the 1950s. It was K. Maeda in Japan who reported in 1953 the first nitroimidazole as a natural product from Nocardia mesenterica with ...
Ria Gupta+5 more
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Development of an open-learning module in natural product chemistry [PDF]
This article describes the author’s personal perspective on the design, production and delivery of an open-learning module in natural product chemistry.
Stephen P. Stanforth
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Molecular docking studies of Triphala with catalytic portion of HMG-CoA reductase enzyme [PDF]
Introduction: Triphala, consisting of three fruits, Phyllanthus emblica L. (Phyllanthaceae), Terminalia bellirica (Gaertn.) Roxb. (Combretaceae), and T.
Prasoborn Rinthong+2 more
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Mining the Metabiome: Identifying Novel Natural Products from Microbial Communities [PDF]
Microbial-derived natural products provide the foundation for most of the chemotherapeutic arsenal available to contemporary medicine. In the face of a dwindling pipeline of new lead structures identified by traditional culturing techniques and an ...
Brady, Sean F.+2 more
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Lemon Juice as a Natural Catalyse for Synthesis of Shiff’s base: A Green Chemistry Approach [PDF]
The advantages of the use of natural catalysts are eco-friendly, inexpensive, high yields, nonhazardous and short reaction times. The utilization of green chemistry techniques is the elimination of solvents during chemical processes or the replacement of
Alikhani, A. (Azadeh)+2 more
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Click-based synthesis and proteomic profiling of lipstatin analogues [PDF]
Using click chemistry to enable both structural diversity and proteome profiling within a natural product derived library, two out of nineteen lipstatin analogues showed similar activity to Orlistat against fatty acid synthase (FAS), but with an improved
Adam+38 more
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Facilitating biomimetic syntheses of borrerine derived alkaloids by means of flow-chemical methods [PDF]
Flow chemistry is widely used nowadays in synthetic chemistry and has increasingly been applied to complex natural product synthesis. However, to date flow chemistry has not found a place in the area of biomimetic synthesis.
Kamptmann, SB, Ley, SV
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