Results 11 to 20 of about 1,495,910 (392)
Natural product chemistry for drug discovery [PDF]
The Journal of Antibiotics, 2011 S. Hashimoto
openaire +3 more sources
Natural product reports (Print), 2020 Covering: up to the end of 2020.The machine learning field can be defined as the study and application of algorithms that perform classification and prediction tasks through pattern recognition instead of explicitly defined rules.
David Prihoda +7 more
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The crystal structure of 13-(pyrazole-1-yl-4-carbonitrile)-matrine, C19H25N5O
Zeitschrift für Kristallographie - New Crystal Structures, 2021 C19H25N5O, monoclinic, P21 (no. 4), a = 16.0600(2) Å, b = 5.3992(1) Å, c = 19.8514(2) Å, β = 94.260(1)°, V = 1716.58(4) Å3, Z = 4, Rgt (F) = 0.0350, wRref(F2) = 0.0908, T = 100.00(10) K.
Li Jun-Jie +8 more
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Integrated Metabolomic–Genomic Workflows Accelerate Microbial Natural Product Discovery
Analytical Chemistry, 2022 The pairing of analytical chemistry with genomic techniques represents a new wave in natural product chemistry. With an increase in the availability of sequencing and assembly of microbial genomes, interrogation into the biosynthetic capability of ...
Nicole E. Avalon, A. Murray, B. Baker
semanticscholar +1 more source
Indonesian Journal of Chemistry, 2010 Preliminary studies on Terong Belanda (C. betacea ) have been carried out in this investigation with an aim to examine the presence of an alkaloid in the fruit of Terong Belanda.
Fredryk Mandey +2 more
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Click-based synthesis and proteomic profiling of lipstatin analogues [PDF]
, 2010 Using click chemistry to enable both structural diversity and proteome profiling within a natural product derived library, two out of nineteen lipstatin analogues showed similar activity to Orlistat against fatty acid synthase (FAS), but with an improved
Adam +38 more
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Perylenequinones from an endophytic Alternaria sp. of Pinus ponderosa
Heliyon, 2018 The differential solvent extraction and further purification of fractions of endophytic Alternaria sp. isolated from Pinus ponderosa led to the isolation of further two perylenequinone compounds as 3,6,6a,9,10-pentahydroxy-7,8-epoxy-4-oxo-4,5,6,6a,6b,7,8,
Mudasir A. Tantry +7 more
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Identification of a new p53/MDM2 inhibitor motif inspired by studies of chlorofusin [PDF]
, 2015 Previous studies on the natural product chlorofusin have shown that the full peptide and azaphilone structure are required for inhibition of the interaction between MDM2 and p53.
Clark +24 more
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Isolation and characterization of starch from Limnophila aromatica
Heliyon, 2019 Starch is one of the digestible natural polymers found in vascular plants. This natural polymer is the primary source of polysaccharides to produce energy for humans.
Cynthia Wijaya +7 more
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Pharmaceuticals, 2022 Nitroimidazole represents one of the most essential and unique scaffolds in drug discovery since its discovery in the 1950s. It was K. Maeda in Japan who reported in 1953 the first nitroimidazole as a natural product from Nocardia mesenterica with ...
Ria Gupta +5 more
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