Results 21 to 30 of about 1,495,910 (392)

The stellar halo of the Galaxy [PDF]

open access: yes, 2008
Stellar halos may hold some of the best preserved fossils of the formation history of galaxies. They are a natural product of the merging processes that probably take place during the assembly of a galaxy, and hence may well be the most ubiquitous ...
A Frebel   +240 more
core   +3 more sources

Furan-site transformations of obacunone as potent insecticidal agents

open access: yesHeliyon, 2018
Furan ring is a key pharmacophore for insecticidal activity of limoninoids. To develop natural-product-based insecticidal agents, a series of furan-site transformations (2, 3 and 3a–j) of obacunone were synthesized by selective bromination and following ...
Ping Xiang   +5 more
doaj   +1 more source

Facilitating biomimetic syntheses of borrerine derived alkaloids by means of flow-chemical methods [PDF]

open access: yes, 2015
Flow chemistry is widely used nowadays in synthetic chemistry and has increasingly been applied to complex natural product synthesis. However, to date flow chemistry has not found a place in the area of biomimetic synthesis.
Kamptmann, SB, Ley, SV
core   +1 more source

Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine

open access: yesNature Communications, 2022
The G-quadruplex formed in KRAS oncogene promoter (KRAS-G4) is a transcriptional modulator and amenable to small molecule targeting. Herein, the authors report the NMR solution structures of a bulge-containing KRAS-G4 that bound to two small molecules ...
Kai-Bo Wang   +10 more
doaj   +1 more source

Transcription activator-like effectors from endosymbiotic bacteria control the reproduction of their fungal host

open access: yesmBio, 2023
The phytopathogenic fungus Rhizopus microsporus harbors a bacterial endosymbiont (Mycetohabitans rhizoxinica) that produces a crucial virulence factor responsible for the characteristic symptoms of rice seedling blight.
Ingrid Richter   +7 more
doaj   +1 more source

Molecular docking studies of Triphala with catalytic portion of HMG-CoA reductase enzyme [PDF]

open access: yesJournal of HerbMed Pharmacology, 2023
Introduction: Triphala, consisting of three fruits, Phyllanthus emblica L. (Phyllanthaceae), Terminalia bellirica (Gaertn.) Roxb. (Combretaceae), and T.
Prasoborn Rinthong   +2 more
doaj   +1 more source

Natural Products Chemistry [PDF]

open access: yesNature, 1964
The Chemistry of Natural Products Special and Introductory Lectures presented at the Second International Symposium on the Chemistry of Natural Products held in Prague, August 27–September 2, 1962. (International Union of Pure and Applied Chemistry, Section of Organic Chemistry, in conjunction with the Czechoslovak Academy of Science and the ...
openaire   +1 more source

Linking a Pharmaceutical Chemistry Workshop to Pharmacy Practice [PDF]

open access: yes, 2014
This paper describes the design and implementation of a workshop to enhance pharmacy students’ appreciation of the importance of chemistry for pharmacy practice.
Adams, Andrew   +5 more
core   +1 more source

Investigating the Initial Steps in the Biosynthesis of Cyanobacterial Sunscreen Scytonemin [PDF]

open access: yes, 2014
The cyanobacterial natural product scytonemin (1) functions as a sunscreen, absorbing harmful UV-A radiation. Using information from a recently identified gene cluster, we propose a biosynthetic route to this pigment.
Balskus, Emily Patricia   +1 more
core   +1 more source

Linker Flexibility Facilitates Module Exchange in Fungal Hybrid PKS-NRPS Engineering [PDF]

open access: yes, 2016
Polyketide synthases (PKSs) and nonribosomal peptide synthetases (NRPSs) each give rise to a vast array of complex bioactive molecules with further complexity added by the existence of natural PKS-NRPS fusions.
Andersen, Mikael Rørdam   +6 more
core   +2 more sources

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