Results 41 to 50 of about 979,824 (352)
Analytical and Preparative Separation of Softwood Lignans by Supercritical Fluid Chromatography
Separations, 2023 Lignans are widespread polyphenolic secondary plant metabolites possessing high biological activity. One of the most promising industrial-scale sources of such compounds is coniferous knotwood, containing a large number of polyphenolic compounds.
Nikolay V. Ul’yanovskii +5 more
doaj +1 more source
Linking a Pharmaceutical Chemistry Workshop to Pharmacy Practice [PDF]
, 2014 This paper describes the design and implementation of a workshop to enhance pharmacy students’ appreciation of the importance of chemistry for pharmacy practice.
Adams, Andrew +5 more
core +1 more source
Dendritic cells steering antigen and leukocyte traffic in lymph nodes
FEBS Letters, EarlyView.Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta +3 more
wiley +1 more source
European Journal of Inflammation, 2012 (+)-2-(1-hydroxyl-4-oxocyclohexyl) ethyl caffeate (HOEC) was isolated from Incarvillea mairei var. granditlora (Wehrhahn) Grierson. The plants of the Incarvillea genus have long been used as folk medicines for the treatment of inflammation-related ...
L. Li +14 more
doaj +1 more source
Natural products chemistry in the third millennium [PDF]
Chemistry Central Journal, 2007 The main directions of Natural Products Chemistry in the Third Millennium are summarized.
openaire +3 more sources
Investigating the Initial Steps in the Biosynthesis of Cyanobacterial Sunscreen Scytonemin [PDF]
, 2014 The cyanobacterial natural product scytonemin (1) functions as a sunscreen, absorbing harmful UV-A radiation. Using information from a recently identified gene cluster, we propose a biosynthetic route to this pigment.
Balskus, Emily Patricia +1 more
core +1 more source
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
Nature Communications, 2017 The biosynthesis of xiamycin, an antimicrobial bacterial indolosesquiterpenoid, involves an unusual cyclization cascade. Here, the authors characterise the XiaF enzyme, which resembles xenobiont-degrading enzymes and is responsible for a hidden indole ...
Susann Kugel +7 more
doaj +1 more source
Linker Flexibility Facilitates Module Exchange in Fungal Hybrid PKS-NRPS Engineering [PDF]
, 2016 Polyketide synthases (PKSs) and nonribosomal peptide synthetases (NRPSs) each give rise to a vast array of complex bioactive molecules with further complexity added by the existence of natural PKS-NRPS fusions.
Andersen, Mikael Rørdam +6 more
core +2 more sources