Results 41 to 50 of about 1,046,985 (303)

Canvass: a crowd-sourced, natural-product screening library for exploring biological space [PDF]

, 2018
NCATS thanks Dingyin Tao for assistance with compound characterization. This research was supported by the Intramural Research Program of the National Center for Advancing Translational Sciences, National Institutes of Health (NIH). R.B.A.
Andrade, Rodrigo B., Bougie, Danielle, Boxer, Matthew B., Brimacombe, Kyle R., Brown, Lauren E., Brown, M Kevin, Burns, Noah Z., Cha, Jin K., Cheff, Dorian M., Cheng, Ken, Clardy, Jon, Clement, Jason A., Coussens, Nathan P., Crooks, Peter A., Cuny, Gregory D., Dillon, Christopher, Dorjsuren, Dorjbal, Eastman, Richard T., Ganor, Jake, Garg, Neil K., Goess, Brian C., Grossman, Robert B., Guha, Rajarshi, Hall, Matthew D., Henderson, Mark J., Huang, Ruili, Hughes, Chambers C., Iannotti, Michael J., Inglese, James, Itkin, Zina, Jadhav, Ajit, Johnston, Jeffrey N., Joullie, Madeleine M., Karavadhi, Surendra, Kearney, Sara E., Kinghorn, A. Douglas, Kingston, David G. I., Klumpp-Thomas, Carleen, Krische, Michael J., Kwon, Ohyun, Lee, Tobie D., Lynch, Caitlin, Maimone, Thomas J., Majumdar, Susruta, Maloney, Katherine N., Mevers, Emily E., Michael, Sam, Mohamed, Enas, Moreno, Jesus, Morrill, Lucas A., Murphy, Brian T., Nagorny, Pavel, Olson, David E., Overman, Larry E., Picazo, Elias, Porco, John A., Ren, Tianjing, Rivas, Fatima, Rohde, Jason M., Ross, Samir A., Roth, Jacob S., Sakamuru, Srilatha, Sarpong, Richmond, Sharma, Indrajeet, Shaw, Jared T., Shen, Ben, Shen, Min, Shi, Wei, Shinn, Paul, Simeonov, Anton, Snyder, John K., Stephenson, Corey R. J., Sun, Wei, Susick, Robert B., Tan, Derek S., Tang, Yi, Taylor, Richard E., Thomson, Regan J., Titus, Steven A., Verano, Alyssa L., Vosburg, David A., Wan, Kanny K., Wu, Jimmy, Wuest, William M., Xia, Menghang, Xu, Zhengren, Yasgar, Adam, Zahoranszky-Kohalmi, Gergely, Zakarian, Armen, Zhang, Ya-Qin, Zhang, Yufeng, Zhao, Jinghua, Zhao, Tongan, Zheng, Wei, Zuo, Zhong   +94 more
core   +1 more source

The crystal structure of a matrine derivative, 13-(methylamine-1-yl) carbodithioate matrine, C17H27N3OS2

Zeitschrift für Kristallographie - New Crystal Structures, 2020
C17H27N3OS2, monoclinic, P21 (no. 4), a = 8.8052(10) Å, b = 10.8860(10) Å, c = 18.6705(2) Å, β = 99.2730(10)°, V = 1766.24(3) Å3, Z = 4, Rgt(F) = 0.0298, wRref(F2) = 0.0802, T = 100.00(10) K.
Hui-Qing He, Fang-Yun Dong, Han-Hui Zhang, Jing-Min Ye, Chun-Can Tan, Xu-Hong Jiang, Zi-Zhao Zheng, Xiao-Jing Lv, Xing-An Cheng   +8 more
doaj   +1 more source

Comprehensive Characterization of Chemical Composition and Antioxidant Activity of Lignan-Rich Coniferous Knotwood Extractives

Antioxidants, 2022
A knotwood of coniferous trees containing large amounts of polyphenolic extractives is considered a promising industrial-scale source of lignans possessing antioxidant properties and other bioactivities.
Nikolay V. Ul’yanovskii, Aleksandra A. Onuchina, Anna V. Faleva, Natalia S. Gorbova, Dmitry S. Kosyakov   +4 more
doaj   +1 more source

Optimization of choline chloride-glycerol based natural deep eutectic solvent for extraction bioactive substances from Cinnamomum burmannii barks and Caesalpinia sappan heartwoods

Heliyon, 2019
Indonesian cassia (Cinnamomum burmannii Blume) is commonly used as a condiment. It reportedly contains a number of major phytochemical constituents such as trans-cinnamaldehyde and coumarin. Sappan wood (Caesalpinia sappan) is a native plant of Southeast
Aditya Sindu Sakti, Fadlina Chany Saputri, Abdul Mun'im   +2 more
doaj   +1 more source

Strain prioritization and genome mining for enediyne natural products [PDF]

, 2016
The enediyne family of natural products has had a profound impact on modern chemistry, biology, and medicine, and yet only 11 enediynes have been structurally characterized to date.
Ben Shen, Christoph Rader, Dong Yang, Filip Van Nieuwerburgh, Hindra, Huiming Ge, Ivana Crnovčičć, Jeffrey D. Rudolf, Jeremy R. Lohman, Li-Xing Zhao, Qihui Teng, Tingting Huang, Xiangcheng Zhu, Xiaohui Yan, Xiuling Li, Yannick Gansemans, Yanwen Duan, Yi Jiang, Yong Huang   +18 more
core   +2 more sources

The crystal structure of the Matrine derivative: 12-(1H-indol-1-yl)dodecahydro-1H,5H,10H-dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one hydrate, C23H29N3O

Zeitschrift für Kristallographie - New Crystal Structures, 2017
C23H29N3O, orthorhombic P212121 (no. 19), a = 8.62130(10) Å, b = 18.25770(10) Å, c = 25.6873(2) Å, V = 4043.31(6) Å3, Z = 8, Rgt(F) = 0.0305, wRref(F2) = 0.0807, T = 293(2) K.
Xing-An Cheng, Zhan-Mei Liu, Wei-Xin Liang, Bo Wu, Xu-Hong Jiang   +4 more
doaj   +1 more source

Antibiofilm formation activity of lupinifolin isolated from Derris reticulata stems against Enterococcus faecalis [PDF]

Journal of HerbMed Pharmacology
Introduction: The biofilm formation capability of Enterococcus faecalis is one of the key virulence factors contributing to its multidrug resistance and therapeutic challenges.
Pawitra Pulbutr, Kridsanun Seelakot, Nicharee Kumphupong, Sakulrat Rattanakiat   +3 more
doaj   +1 more source

Non-natural Olefin Cyclopropanation Catalyzed by Diverse Cytochrome P450s and Other Hemoproteins [PDF]

, 2014
Recent work has shown that engineered variants of cytochrome P450_(BM3) (CYP102A1) efficiently catalyze non-natural reactions, including carbene and nitrene transfer reactions.
Arnold, Frances H., Dodani, Sheel C., Heel, Thomas, McIntosh, John A., Meyerowitz, Joseph T.   +4 more
core   +1 more source

Enzymatic functionalization of carbon-hydrogen bonds [PDF]

, 2011
The development of new catalytic methods to functionalize carbon–hydrogen (C–H) bonds continues to progress at a rapid pace due to the significant economic and environmental benefits of these transformations over traditional synthetic methods.
Arnold, Frances H., Coelho, Pedro S., Lewis, Jared C.   +2 more
core   +1 more source

Ion Exchange-Precipitation for Nutrient Recovery from Dilute Wastewater [PDF]

, 2015
Regulated phosphorus (P) and nitrogen (N) discharges and the cost of fertilizer provide economic drivers for nutrient removal and recovery from wastewater.
Mayer, Brooke K., Williams, A. T., Zitomer, Daniel   +2 more
core   +2 more sources