Results 51 to 60 of about 1,745,354 (410)

An update on cyclohepta[b]indoles [PDF]

, 2021
The cyclohepta[b]indole scaffold constitutes a salient structural motif in natural products as well as in men-made pharmaceutically active ingredients. Cyclohepta[b]indoles consist of an indole nucleus fused to a seven-membered carbacycle.
Benedix, Lars, Gierok, Jan, Hiersemann, Martin   +2 more
core  

Phenolic profiling and therapeutic potential of local flora of Azad Kashmir; In vitro enzyme inhibition and antioxidant

Open Chemistry, 2017
The current study supports the phytochemical screening, evaluation of antioxidant and enzyme inhibition potential and correlations between antioxidant activities and phenolics of Rumex dentatus (Family: Polygonaceae), Mentha spicata (Family: Lamiaceae ...
Raza Muhammad Asam, Danish Muhammad, Mushtaq Mahvish, Sumrra Sajjad Hussain, Saqib Zenab, Rehman Shafiq Ur   +5 more
doaj   +1 more source

Antibiofilm formation activity of lupinifolin isolated from Derris reticulata stems against Enterococcus faecalis [PDF]

Journal of HerbMed Pharmacology
Introduction: The biofilm formation capability of Enterococcus faecalis is one of the key virulence factors contributing to its multidrug resistance and therapeutic challenges.
Pawitra Pulbutr, Kridsanun Seelakot, Nicharee Kumphupong, Sakulrat Rattanakiat   +3 more
doaj   +1 more source

Mining the Metabiome: Identifying Novel Natural Products from Microbial Communities [PDF]

, 2014
Microbial-derived natural products provide the foundation for most of the chemotherapeutic arsenal available to contemporary medicine. In the face of a dwindling pipeline of new lead structures identified by traditional culturing techniques and an ...
Brady, Sean F., Milshteyn, Aleksandr, Schneider, Jessica S.   +2 more
core   +1 more source

The crystal structure of a matrine derivative: 41S,7aS,12S,13aR,13bR)-12-(4-methylpiperazin-1-yl)dodecahydro-1H,5H,10H-dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one, C20H34N4O

Zeitschrift für Kristallographie - New Crystal Structures, 2018
C20H34N4O, triclinic, P1 (no. 1), a = 7.8545(6) Å, b = 10.8802(9) Å, c = 12.3714(9) Å, α = 73.200(7)°, β = 75.372(6)°, γ = 71.091(7)°, V = 942.65(13) Å3, Z = 2, Rgt(F) = 0.0591, wRref(F2) = 0.1641, T = 293(2) K.
Cheng Xing-An, Zhan-Mei Liu, Bo Wu, Su-Qing Huang, Xia-Ling Xiong, Xu-Hong Jiang   +5 more
doaj   +1 more source

The crystal structure of the Matrine derivative: 12-(1H-indol-1-yl)dodecahydro-1H,5H,10H-dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one hydrate, C23H29N3O

Zeitschrift für Kristallographie - New Crystal Structures, 2017
C23H29N3O, orthorhombic P212121 (no. 19), a = 8.62130(10) Å, b = 18.25770(10) Å, c = 25.6873(2) Å, V = 4043.31(6) Å3, Z = 8, Rgt(F) = 0.0305, wRref(F2) = 0.0807, T = 293(2) K.
Xing-An Cheng, Zhan-Mei Liu, Wei-Xin Liang, Bo Wu, Xu-Hong Jiang   +4 more
doaj   +1 more source

The chemical space of terpenes: insights from data science and AI [PDF]

arXiv, 2021
Terpenes are a widespread class of natural products with significant chemical and biological diversity and many of these molecules have already made their way into medicines. Given the thousands of molecules already described, the full characterization of this chemical space can be a challenging task when relying in classical approaches.
arxiv  

Natural Product Nitric Oxide Chemistry: New Activity of Old Medicines [PDF]

, 2012
The use of complementary and alternative medicine (CAM) as a therapy and preventative care measure for cardiovascular diseases (CVD) may prove to be beneficial when used in conjunction with or in place of conventional medicine.
Bryan, Nathan S., Jiang, Hong, Parthasarathy, Deepa K., Torregrossa, Ashley C.   +3 more
core   +3 more sources

Analytical and Preparative Separation of Softwood Lignans by Supercritical Fluid Chromatography

Separations, 2023
Lignans are widespread polyphenolic secondary plant metabolites possessing high biological activity. One of the most promising industrial-scale sources of such compounds is coniferous knotwood, containing a large number of polyphenolic compounds.
Nikolay V. Ul’yanovskii, Aleksandra A. Onuchina, Denis V. Ovchinnikov, Anna V. Faleva, Natalia S. Gorbova, Dmitry S. Kosyakov   +5 more
doaj   +1 more source

An Artificial Chemistry Implementation of a Gene Regulatory Network [PDF]

arXiv, 2022
Gene Regulatory Networks are networks of interactions in biological organisms responsible for determining the production levels of proteins and peptides. Proteins are workers of a cell factory, and their production defines the goal of a cell and its development.
arxiv