Results 51 to 60 of about 979,824 (352)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Fantastic Leaves and What's Inside Them: Chemistry and Biochemical Imaging of Natural Products in Western Australian Plants [PDF]
, 2021 Natural products are used in a wide variety of fields ranging from pharmaceuticals to agriculture. 6-Hydroxycaryophyllenes are a class of natural product isolated from the leaf resin of Scaevola crassifolia Labill.
Rajagopalan, Aswin
core
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Toxin-Producing Endosymbionts Shield Pathogenic Fungus against Micropredators
mBio, 2022 The fungus Rhizopus microsporus harbors a bacterial endosymbiont (Mycetohabitans rhizoxinica) for the production of the antimitotic toxin rhizoxin.
Ingrid Richter +10 more
doaj +1 more source
Borate esters: Simple catalysts for the sustainable synthesis of complex amides [PDF]
, 2017 Chemical reactions for the formation of amide bonds are among the most commonly used transformations in organic chemistry, yet they are often highly inefficient. A novel protocol for amidation using a simple borate ester catalyst is reported.
Boulton, LT, Sabatini, MT, Sheppard, TD
core +1 more source
FEBS Letters, EarlyView.Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke +2 more
wiley +1 more source
Perylenequinones from an endophytic Alternaria sp. of Pinus ponderosa
Heliyon, 2018 The differential solvent extraction and further purification of fractions of endophytic Alternaria sp. isolated from Pinus ponderosa led to the isolation of further two perylenequinone compounds as 3,6,6a,9,10-pentahydroxy-7,8-epoxy-4-oxo-4,5,6,6a,6b,7,8,
Mudasir A. Tantry +7 more
doaj
Green Processing and Synthesis, 2019 Nature and nanotechnology have not yet achieved a lucid correlation in the field of science but together they have exhibited immense potential towards the advancement and modification in future science and technology.
Fowsiya J. +7 more
doaj +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Isolation and characterization of starch from Limnophila aromatica
Heliyon, 2019 Starch is one of the digestible natural polymers found in vascular plants. This natural polymer is the primary source of polysaccharides to produce energy for humans.
Cynthia Wijaya +7 more
doaj