Results 71 to 80 of about 1,189,605 (351)
Toxin-Producing Endosymbionts Shield Pathogenic Fungus against Micropredators
mBio, 2022 The fungus Rhizopus microsporus harbors a bacterial endosymbiont (Mycetohabitans rhizoxinica) for the production of the antimitotic toxin rhizoxin.
Ingrid Richter +10 more
doaj +1 more source
Ion Exchange-Precipitation for Nutrient Recovery from Dilute Wastewater [PDF]
, 2015 Regulated phosphorus (P) and nitrogen (N) discharges and the cost of fertilizer provide economic drivers for nutrient removal and recovery from wastewater.
Mayer, Brooke K. +2 more
core +2 more sources
Neurotrophic Natural Products: Chemistry and Biology [PDF]
Angewandte Chemie International Edition, 2013 AbstractNeurodegenerative diseases and spinal cord injury affect approximately 50 million people worldwide, bringing the total healthcare cost to over 600 billion dollars per year. Nervous system growth factors, that is, neurotrophins, are a potential solution to these disorders, since they could promote nerve regeneration.
Xu, Jing +2 more
openaire +4 more sources
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Heliyon, 2019 Plants of the Asteraceae family have been used in traditional medicine for centuries due to their main antimicrobial and analgesic activities. A liniment from Artemisia californica has recently been tested on patients affected by either acute pain or ...
Filomena Perri +8 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Nature Communications, 2017 The biosynthesis of xiamycin, an antimicrobial bacterial indolosesquiterpenoid, involves an unusual cyclization cascade. Here, the authors characterise the XiaF enzyme, which resembles xenobiont-degrading enzymes and is responsible for a hidden indole ...
Susann Kugel +7 more
doaj +1 more source
Chemical synthesis and cytotoxicity of neo-glycolipids; rare sugar-glycerol-lipid compounds
Heliyon, 2018 Rare sugars are defined as monosaccharides and their derivatives, which rarely exist in nature and have various beneficial effects on organisms, biomaterials and foods.
Keisuke Hirata +4 more
doaj +1 more source
Heterologous expression of bacterial natural product biosynthetic pathways.
Natural product reports (Print), 2019 Covering: 2013 to June 2018Heterologous expression of natural product biosynthetic pathways is of increasing interest in microbial biotechnology, drug discovery and optimization. It empowers not only the robust production of valuable biomolecules in more
Liujie Huo +5 more
semanticscholar +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source