Results 101 to 110 of about 18,110,415 (308)

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

A study on the photoisomerization of phenylpropanoids and the differences in their radical scavenging activity using in-situ NMR spectroscopy and on-line radical scavenging activity analysis

Applied Biological Chemistry
Phenylpropanoids are naturally occurring secondary metabolites that exhibit various biological activities such as ultra-violet (UV) light protection and reactive-oxygen species (ROS) scavenging.
Sangah Park, Hojin Kim, Miyeon Bang, Byung-Hun Um, Jin Wook Cha   +4 more
doaj   +1 more source

Induction of PR-10 genes and metabolites in strawberry plants in response to Verticillium dahliae infection

BMC Plant Biology, 2019
Background The soil-borne vascular pathogen Verticillium dahliae causes severe wilt symptoms in a wide range of plants including strawberry (Fragaria × ananassa). To enhance our understanding of the effects of V.
Fatma Besbes, Ruth Habegger, Wilfried Schwab   +2 more
doaj   +1 more source

The isolation and characterization of natural products from marine plants and microorganisms [PDF]

, 2009
Many organisms, including plants, microbes and invertebrates produce compounds called as natural products. The production of natural products often confers some advantage to the producing organism such as chemical defense from predators.
Krzysiak, Amanda J., NC DOCKS at The University of North Carolina Wilmington   +1 more
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Characterization, Composition, and Bioactive Potential of Assa-Peixe (Vernonia sp.) Honey

Journal of Food Quality
In this study, pollen content, physicochemical parameters, quantification of phenolics and flavonoids, antioxidant capacity, UV spectrum scan, and substance identification by LC-HRMS were evaluated in Assa-peixe honey.
Pedro Henrique Fonseca Veloso, Lilianny Mendes Soares Araújo, Veronica de Melo Sacramento, Dario Alves de Oliveira, Luciano Fernandes de Souza, Nathália da Costa Pires, Carlos Leomar Zani, Tânia Maria de Almeida Alves, Vanessa de Andrade Royo   +8 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Phytochemicals and Estrogen-Receptor Agonists from the Aerial Parts of Liriope platyphylla

Molecules, 2015
One new benzofuran, (2R)-(2',4'-dihydroxybenzyl)-6,7-methylenedioxy-2,3-dihydrobenzofuran (1), one new phenylisocoumarin, 3-(2'-hydroxyphenyl)-6,8-dihydroxy-7-methoxy-isocoumarin (2), and one new benzofuroisocoumarin, platyphyllarin C (3), were isolated ...
Yu-Chi Tsai, Chia-Chun Hsu, Mohamed El-Shazly, Shang-Yu Chiang, Chau-Chung Wu, Chin-Chung Wu, Wan-Chun Lai, Ming-Hong Yen, Yang-Chang Wu, Fang-Rong Chang   +9 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Buddlejasaponin IV inhibits proliferation and migration via STAT3 suppression in gefitinib-resistant non-small cell lung cancer cells

BMC Complementary Medicine and Therapies
Background Lung cancer is a leading cause of death globally, with non-small-cell lung cancer (NSCLC) often developing resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs). This study explored the efficacy and mechanism of
Sung Chul Jang, Donghwa Kim, Jaeho Han, Dong Hyun Moon, Eun Seo Bae, Chae Won Ock, Hyen Joo Park, Sang Kook Lee   +7 more
doaj   +1 more source