Results 81 to 90 of about 18,110,415 (308)
Techniques for extraction and isolation of natural products: a comprehensive review
Chinese Medicine, 2018 Natural medicines were the only option for the prevention and treatment of human diseases for thousands of years. Natural products are important sources for drug development.
Qing-Wen Zhang, Ligen Lin, W. Ye
semanticscholar +1 more source
Cheminformatics Explorations of Natural Products
, 2019 The chemistry of natural products is fascinating and has continuously attracted the attention of the scientific community for many reasons including, but not limited to, biosynthesis pathways, chemical diversity, the source of bioactive compounds and ...
Prieto-Martínez, FD +5 more
core +1 more source
Editorial to the Special Issue–“Natural Products and Drug Discovery”
, 2020 Natural products hold a prominent position in the discovery and development of many drugs used nowadays, with diverse indications for human and animal health [...
Pinarosa Avato
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Journal of Food QualityEdible bird’s nest (EBN) is an animal product with the world’s highest market price due to its value. The nests are made exclusively from the saliva secreted by swiftlet, a species of bird native to Southeast Asia.
Nurin Naziha Zulkefle +6 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Anti-aging Effects and Main Chemical Constituents of Stem Extracts
Natural Product CommunicationsObjective: To investigate the anti-aging effects and the main chemical constituents of Spiraea salicifolia stem extracts. Methods: The anti-aging effects were investigated by evaluating the antioxidant, anti-wrinkle, and anti-inflammatory properties. The
Gwee Kyo Park +7 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Natural Products Targeting PI3K/AKT in Myocardial Ischemic Reperfusion Injury: A Scoping Review
, 2023 This scoping review aimed to summarize the effects of natural products targeting phosphoinositide-3-kinases/serine/threonine kinase (PI3K/AKT) in myocardial ischemia-reperfusion injury (MIRI). The review details various types of natural compounds such as
Syarifah Aisyah Syed Abd Halim +3 more
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Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source