HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Computational Search for Potential COVID-19 Drugs from FDA-Approved Drugs and Small Molecules of Natural Origin Identifies Several Anti-Virals and Plant Products [PDF]
, 2020 Abhishek Sharma +2 more
openalex +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Automated, self-resistance gene-guided, and high-throughput genome mining of bioactive natural products from Streptomyces [PDF]
, 2023 Yujie Yuan +4 more
openalex +1 more source
A Comparison of Wholesaler/Retailer Business Characteristics of Natural Products between Ghana and Rwanda [PDF]
The usage of natural products is becoming an increasingly common consumer phenomenon due to increasing health consciousness, and because of their naturalness, and medicinal qualities of the products.
Acquaye, Dan +8 more
core +1 more source
Hepatotprotective Natural Products [PDF]
, 2005 Medicinal herbs are significant source of pharmaceutical drugs. Latest trends have shown increasing demand of phytodrugs and some medicinal herbs have proven hepatotprotective potential.
Malhotra, Samir, Singh, Amrit Pal
core +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
LRR1 involved in the abscisic acid signaling pathway to regulate the early growth and development of Arabidopsis thaliana [PDF]
PeerJBackground Living organisms possess the remarkable capacity to swiftly adapt to fluctuations in their environment. In the context of cell signal transduction, a significant challenge lies in ensuring the effective perception of external signals and the ...
Xiaoyang Xie +8 more
doaj +2 more sources
TARGETABLE MARKET SEGMENTS FOR NATURAL PORK PRODUCTS [PDF]
A survey of consumers established willingness to pay for natural pork products. Probit estimation was used to define targetable market segments for ham and pork chops. High-income, frequent pork consumers, and those most concerned about the use of growth
Grannis, Jennifer L., Thilmany, Dawn D.
core +1 more source