Results 71 to 80 of about 1,462,911 (314)

Natural Products and Cancer

open access: yesNutrients, 2023
Natural and dietary compounds are known to offer protection and affect the pathogeneses of numerous chronic diseases [...]
openaire   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

InertDB as a generative AI-expanded resource of biologically inactive small molecules from PubChem

open access: yesJournal of Cheminformatics
The development of robust artificial intelligence (AI)-driven predictive models relies on high-quality, diverse chemical datasets. However, the scarcity of negative data and a publication bias toward positive results often hinder accurate biological ...
Seungchan An   +9 more
doaj   +1 more source

A pharmaceutical model for the molecular evolution of microbial natural products [PDF]

open access: yes, 2020
Microbes are talented chemists with the ability to generate tremendously complex and diverse natural products which harbor potent biological activities.
David P. Fewer   +3 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Investigation of the natural products composition from the seaweed ulva capensis [PDF]

open access: yes, 2019
>Magister Scientiae - MScIn modern society, diversity of marine macroalgae has become an inspiration for pharmaceutical companies and researchers because of their numerous health benefits, and a great deal of interest has developed towards the isolation ...
Thwala, Sazi Selby
core   +1 more source

Characterization, Composition, and Bioactive Potential of Assa-Peixe (Vernonia sp.) Honey

open access: yesJournal of Food Quality
In this study, pollen content, physicochemical parameters, quantification of phenolics and flavonoids, antioxidant capacity, UV spectrum scan, and substance identification by LC-HRMS were evaluated in Assa-peixe honey.
Pedro Henrique Fonseca Veloso   +8 more
doaj   +1 more source

Induction of PR-10 genes and metabolites in strawberry plants in response to Verticillium dahliae infection

open access: yesBMC Plant Biology, 2019
Background The soil-borne vascular pathogen Verticillium dahliae causes severe wilt symptoms in a wide range of plants including strawberry (Fragaria × ananassa). To enhance our understanding of the effects of V.
Fatma Besbes   +2 more
doaj   +1 more source

Growing Importance of Natural Products Research

open access: yes, 2019
Natural products and preparations based on them play a stable and ever-increasing role in human and veterinary medicine, agriculture, in food and the cosmetic industry, and in other increasing numbers of fields [...
Pavel B. Drasar, Vladimir A. Khripach
core   +1 more source

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