Results 71 to 80 of about 4,377,426 (345)
Natural star products on symplectic manifolds and quantum moment maps
, 2003 We define a natural class of star products: those which are given by a series of bidifferential operators which at order $k$ in the deformation parameter have at most $k$ derivatives in each argument.
Gutt, Simone, Rawnsley, John
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Indole diterpenoid natural products as the inspiration for new synthetic methods and strategies. [PDF]
, 2017 Indole terpenoids comprise a large class of natural products with diverse structural topologies and a broad range of biological activities. Accordingly, indole terpenoids have and continue to serve as attractive targets for chemical synthesis.
Corsello, Michael A +2 more
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Plant Products as Biopesticides: Building On Traditional Knowledge of Vrkshayurveda: Traditional Indian Plant Science [PDF]
, 2008 Today there is a global search for alternatives to chemical pesticides and as part of this process there are various efforts to test the use and efficacy of natural products for pest control and crop protection. Our Centre has been involved in exploring
Arumugasamy, Mr. S. +3 more
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Checkpoint blockade and the stem‐like T cell trade‐off
Molecular Oncology, EarlyView.Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Laxative Effect of Glutinous Rice Banana Enzyme on Constipated Mice
Shipin gongye ke-jiObjective: Exploring the laxative and intestinal protective effects of glutinous rice banana enzyme (GRBE) on constipated mice. Methods: A mouse constipation model was established by administering loperamide hydrochloride (LH).
Lilang LI +8 more
doaj +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Autophagy and multidrug resistance in cancer
Chinese Journal of Cancer, 2017 Multidrug resistance (MDR) occurs frequently after long-term chemotherapy, resulting in refractory cancer and tumor recurrence. Therefore, combatting MDR is an important issue. Autophagy, a self-degradative system, universally arises during the treatment
Ying-Jie Li +7 more
doaj +1 more source
Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action. [PDF]
, 2018 Bioactive natural products have evolved to inhibit specific cellular targets and have served as lead molecules for health and agricultural applications for the past century1-3.
Bat-Erdene, Undramaa +9 more
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