Results 51 to 60 of about 8,670,110 (314)
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Natural Products from the Genus Tephrosia
, 2014 The genus Tephrosia, belonging to the Leguminosae family, is a large pantropical genus of more than 350 species, many of which have important traditional uses in agriculture.
Tao Yan +4 more
core +1 more source
Journal of Future Foods, 2023 This study sought to investigate whether Ganoderma lucidum polysaccharide (GLP) has a protective effect on lipopolysaccharide (LPS)-induced inflammatory injury to mammary epithelial HC-11 cells and to characterize the mechanism involved.
Yi Fan +7 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Food & Medicine HomologyArtemisia argyi polysaccharide (AAP) is an important active component extracted from the leaves of A. argyi. Currently, the effects of AAP in mouse model of intestinal inflammation are unclear.
Er-Juan Ning +10 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
A Chemometric Analysis of Deep-Sea Natural Products
, 2019 Deep-sea natural products have been created by unique marine organisms that thrive in a challenging environment of extreme conditions for its inhabitants.
Lisa I. Pilkington
core +1 more source
Anti-aging Effects and Main Chemical Constituents of Stem Extracts
Natural Product CommunicationsObjective: To investigate the anti-aging effects and the main chemical constituents of Spiraea salicifolia stem extracts. Methods: The anti-aging effects were investigated by evaluating the antioxidant, anti-wrinkle, and anti-inflammatory properties. The
Gwee Kyo Park +7 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Nat. Prod. Rep., 2012 This review of marine natural products for 2014 describes 1378 new compounds and reports structural revisions or assignments of absolute configuration for previously reported compounds. Since 1965 MNP chemists have made ∼9000 collections worldwide yielding ∼25 700 new MNPs. The rate of discovery of MNPs by region is examined in this review.
John W. Blunt +4 more
openaire +11 more sources