Results 31 to 40 of about 1,260,577 (268)

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko, Holger N. Lode, Alberto Garaventa, Carla Manzitti, Roberto Luksch, Dominique Valteau‐Couanet, Marion Gambart, John Anderson, Juliet Gray, Adela Canete, Lucas Moreno, Aleksandra Wieczorek, Cormac Owens, Shifra Ash, Isaac Yaniv, Genevieve Laureys, Hans Loibner, Katarzyna Śladowska, Ruth Ladenstein, Paweł Kawalec   +19 more
wiley   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Artemisia argyi polysaccharide alleviates intestinal inflammation and intestinal flora dysbiosis in lipopolysaccharide-treated mice

Food & Medicine Homology
Artemisia argyi polysaccharide (AAP) is an important active component extracted from the leaves of A. argyi. Currently, the effects of AAP in mouse model of intestinal inflammation are unclear.
Er-Juan Ning, Chao-Wei Sun, Xue-Fang Wang, Ling Chen, Fei-Fei Li, Li-Xian Zhang, Lu-Peng Wang, Yan-Ni Ma, Jie Zhu, Xiao Li, Wei Wang   +10 more
doaj   +1 more source

Phytochemicals, Antiinflammatory, and Analgesic Effects of the Ethanol Extract From the Leaves of Wall. ex C. B. Clarke

Natural Product Communications, 2022
In the current study, the ethanol extract of Premna flavescens leaves (EPF) was evaluated for its in vivo antiinflammatory, analgesic potentials, and acute oral toxicity. The analgesic potential was assessed through the acetic acid-induced writhing test,
Ha Minh Le, Phuong Thi Ngo, Anh Tuan Nguyen, Huyen Thi Thanh Do   +3 more
doaj   +1 more source

Plausible influence of atorvastatin and dietary legumes (horsegram and groundnut) in dyslipidemia in experimental rodents

Phytomedicine Plus, 2021
Background: Dyslipidemia a common pathology in metabolic syndrome results due to various factors. Although statins are proven for its beneficial role in the management of hyperlipidemia, plant-based foods and their ingredients are still a cornerstone of ...
Malarvizhi R, Sugumar Mani, Veeresh K. Sali, Nithya P, Vidhushini Sekar, Hannah R. Vasanthi   +5 more
doaj   +1 more source

Marine natural products

Nat. Prod. Rep., 2012
This review of marine natural products for 2014 describes 1378 new compounds and reports structural revisions or assignments of absolute configuration for previously reported compounds. Since 1965 MNP chemists have made ∼9000 collections worldwide yielding ∼25 700 new MNPs. The rate of discovery of MNPs by region is examined in this review.
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro, Michèle R. Prinsep   +4 more
openaire   +11 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

THE PRODUCTION AND NATURE OF STREPTOCOLYSIN. [PDF]

JAMA: The Journal of the American Medical Association, 1903
In 1897 Bordet1drew attention to the fact that there generally is more or less hemolysis in the blood of a rabbit which has died of streptococcus infection. This hemolysis is not constantly observed, but was present, for instance, in 37 of 40 rabbits dying of streptococcus infection, in which it was looked for in this laboratory during the last eight ...
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source