Results 21 to 30 of about 1,462,911 (314)
With the recent development of chemical analysis technology, attention has been placed on natural light-sensitive compounds that exhibit photoreactivity to expand the structural diversity of natural product chemistry. Photochemical reactions that proceed
InWha Park +6 more
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Functional Properties of Natural Products and Human Health
In this Special Issue are collected original research articles, short communications, and reviews on new perspectives for the chemical and functional properties of natural products, including the molecular mechanisms behind the therapeutic effects of ...
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A Natural Love of Natural Products [PDF]
Recent research on the chemistry of natural products from the author's group that led to the receipt of the ACS Ernest Guenther Award in the Chemistry of Natural Products is reviewed. REDOR NMR and synthetic studies established the T-taxol conformation as the bioactive tubulin-binding conformation, and these results were confirmed by the synthesis of ...
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Drug Development Inspired by Natural Products II
For centuries, natural products have been rich sources of healing compounds for different cultures [...
Patricia Rijo
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Physalin A regulates the Nrf2 pathway through ERK and p38 for induction of detoxifying enzymes
Background Physalin A isolated from Physalis alkekengi var. franchetii has been known to have many pharmacological properties. However, its effect through the Nrf2 pathway has not yet been elucidated.
Ji Min Shin +4 more
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Background Despite continued efforts using chemical similarity methods in virtual screening, currently developed approaches suffer from time-consuming multistep procedures and low success rates.
Prasannavenkatesh Durai +3 more
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Natural Products as Anticancer Agents: Current Status and Future Perspectives
Natural products have been an invaluable and useful source of anticancer agents over the years. Several compounds have been synthesized from natural products by modifying their structures or by using naturally occurring compounds as building blocks in ...
Abid Naeem +13 more
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Natural Products for Medicine [PDF]
Throughout human history, natural products—including terrestrial plants, animal products, marine organisms, and products of microorganismal fermentation—have been used in traditional medicines. This historical experience with natural products as therapeutic agents has evolved to sophisticated isolation of active chemical entities from ...
Shibata, Masa-Aki +3 more
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Novel Thioethers of Dihydroartemisinin Exhibiting Their Biological Activities
Eleven conjugates between dihydroartemisinin (DHA) with thiols containing both ether and thioether bonds were designed, synthesized by a two-step procedure including etherification and S-alkylation.
Ngoc Hung Truong +6 more
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Natural Products Targeting the Mitochondria in Cancers
There are abundant sources of anticancer drugs in nature that have a broad prospect in anticancer drug discovery. Natural compounds, with biological activities extracted from plants and marine and microbial metabolites, have significant antitumor effects,
Yue Yang, Ning Li, Yi Zhang, Ping-Ya He
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