Results 11 to 20 of about 4,377,426 (345)
GPX8 regulates clear cell renal cell carcinoma tumorigenesis through promoting lipogenesis by NNMT
Journal of Experimental & Clinical Cancer Research, 2023 Background Clear cell renal cell carcinoma (ccRCC), with its hallmark phenotype of high cytosolic lipid content, is considered a metabolic cancer. Despite the implication of this lipid-rich phenotype in ccRCC tumorigenesis, the roles and regulators of de
Tin Tin Manh Nguyen +11 more
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Antioxidants, 2022 With the recent development of chemical analysis technology, attention has been placed on natural light-sensitive compounds that exhibit photoreactivity to expand the structural diversity of natural product chemistry. Photochemical reactions that proceed
InWha Park +6 more
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Natural products genomics [PDF]
Microbial Biotechnology, 2008 Secondary metabolites (or natural products) are often synthesized by multi‐modular, multi‐domain proteins called non‐ribosomal peptide synthetases (NRPS) and polyketide synthases (PKS). Various well‐known metabolites produced by microorganisms are listed in Table 1, and examples of structures are shown in Fig. 1. In particular, Streptomyces species are
Siezen, R.J., Khayatt, B.
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Bioactive Natural Products [PDF]
Journal of Chemistry, 2013 Bioactive natural products have never ceased to play an important role in the search of novel therapeutic agents. Natural products from the nature such as the plant and marine sources form an integral part of the living system, and they have existed ever since the beginning of life.Therefore, it is undeniable that works related to natural products ...
Hadi, A. Hamid A. +2 more
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Biosynthesis of thiocarboxylic acid-containing natural products. [PDF]
, 2018 Thiocarboxylic acid-containing natural products are rare and their biosynthesis and biological significance remain unknown. Thioplatensimycin (thioPTM) and thioplatencin (thioPTN), thiocarboxylic acid congeners of the antibacterial natural products ...
Deng, Youchao +9 more
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Physalin A regulates the Nrf2 pathway through ERK and p38 for induction of detoxifying enzymes
BMC Complementary and Alternative Medicine, 2019 Background Physalin A isolated from Physalis alkekengi var. franchetii has been known to have many pharmacological properties. However, its effect through the Nrf2 pathway has not yet been elucidated.
Ji Min Shin +4 more
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Dithiolopyrrolone Natural Products : Isolation, Synthesis and Biosynthesis [PDF]
, 2013 Peer reviewedPublisher ...
Deng, Hai +3 more
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BMC Bioinformatics, 2020 Background Despite continued efforts using chemical similarity methods in virtual screening, currently developed approaches suffer from time-consuming multistep procedures and low success rates.
Prasannavenkatesh Durai +3 more
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Novel Thioethers of Dihydroartemisinin Exhibiting Their Biological Activities
Heteroatom Chemistry, 2023 Eleven conjugates between dihydroartemisinin (DHA) with thiols containing both ether and thioether bonds were designed, synthesized by a two-step procedure including etherification and S-alkylation.
Ngoc Hung Truong +6 more
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Strain prioritization and genome mining for enediyne natural products [PDF]
, 2016 The enediyne family of natural products has had a profound impact on modern chemistry, biology, and medicine, and yet only 11 enediynes have been structurally characterized to date.
Ben Shen +18 more
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