Results 91 to 100 of about 1,462,911 (314)
Applied Biological Chemistry, 2023 The high prevalence of methicillin-resistant Staphylococcus aureus (MRSA) infection threatens the effectiveness of current clinical settings. Antimicrobial photodynamic therapy (APDT) is a promising alternative to antibiotics for treating infections due ...
Ngoc Minh Ha +9 more
doaj +1 more source
The isolation and characterization of natural products from marine plants and microorganisms [PDF]
, 2009 Many organisms, including plants, microbes and invertebrates produce compounds called as natural products. The production of natural products often confers some advantage to the producing organism such as chemical defense from predators.
Krzysiak, Amanda J. +1 more
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Natural Product Reports, 2018 This review of 2016 literature describes the structures and biological activities of 1277 new marine natural products and the structure revision and absolute configuration of previously reported MNPs. The chemical diversity of 28 609 MNPs reported since 1957 is also investigated and compared to that of approved drugs.
John W. Blunt +5 more
openaire +4 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Mining Microbial Communities: Exploring Symbiotic Bacteria as a Source of New Natural Products [PDF]
, 2013 As ubiquitous inhabitants of Earth, bacteria represent a diverse resource in the search for new natural products. In order for the field of natural products to progress, new and exciting sources of biodiversity must be continually accessed.
Theodore, Christine M.
core
Anti-Alzheimer’s Natural Products Derived from Plant Endophytic Fungi
, 2023 Alzheimer’s is the most common cause of dementia worldwide and seriously affects patients’ daily tasks. Plant endophytic fungi are known for providing novel and unique secondary metabolites with diverse activities.
Li Liu +4 more
core +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Laxative Effect of Glutinous Rice Banana Enzyme on Constipated Mice
Shipin gongye ke-jiObjective: Exploring the laxative and intestinal protective effects of glutinous rice banana enzyme (GRBE) on constipated mice. Methods: A mouse constipation model was established by administering loperamide hydrochloride (LH).
Lilang LI +8 more
doaj +1 more source