Results 91 to 100 of about 8,670,110 (314)
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Natural Product Reports, 2018 This review of 2016 literature describes the structures and biological activities of 1277 new marine natural products and the structure revision and absolute configuration of previously reported MNPs. The chemical diversity of 28 609 MNPs reported since 1957 is also investigated and compared to that of approved drugs.
John W. Blunt +5 more
openaire +4 more sources
Characterization, Composition, and Bioactive Potential of Assa-Peixe (Vernonia sp.) Honey
Journal of Food QualityIn this study, pollen content, physicochemical parameters, quantification of phenolics and flavonoids, antioxidant capacity, UV spectrum scan, and substance identification by LC-HRMS were evaluated in Assa-peixe honey.
Pedro Henrique Fonseca Veloso +8 more
doaj +1 more source
Phytochemicals and Estrogen-Receptor Agonists from the Aerial Parts of Liriope platyphylla
Molecules, 2015 One new benzofuran, (2R)-(2',4'-dihydroxybenzyl)-6,7-methylenedioxy-2,3-dihydrobenzofuran (1), one new phenylisocoumarin, 3-(2'-hydroxyphenyl)-6,8-dihydroxy-7-methoxy-isocoumarin (2), and one new benzofuroisocoumarin, platyphyllarin C (3), were isolated ...
Yu-Chi Tsai +9 more
doaj +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
, 2017 The discovery of novel and/or new bioactive natural products from biota sources is often confounded by the reisolation of known natural products. Dereplication strategies that involve the analysis of NMR and MS spectroscopic data to infer structural ...
Carlos L. Zani +5 more
core +1 more source
, 2020 The International Symposium on Marine Natural Products (MaNaPro) happened for the first time in 1975 in the city of Aberdeen, Scotland, organized by Professor Ronald H [...]
Emiliano Manzo +5 more
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
The isolation and characterization of natural products from marine plants and microorganisms [PDF]
, 2009 Many organisms, including plants, microbes and invertebrates produce compounds called as natural products. The production of natural products often confers some advantage to the producing organism such as chemical defense from predators.
Krzysiak, Amanda J. +1 more
core
Synthesis and Structural Modification of Marine Natural Products
, 2017 In the last decades, marine natural products (MNPs), have attracted extensive interest from both chemists and pharmacologists due to their chemical and bioactive diversities.
Juan Zhang +4 more
core +1 more source