Results 111 to 120 of about 8,670,110 (314)

Laxative Effect of Glutinous Rice Banana Enzyme on Constipated Mice

Shipin gongye ke-ji
Objective: Exploring the laxative and intestinal protective effects of glutinous rice banana enzyme (GRBE) on constipated mice. Methods: A mouse constipation model was established by administering loperamide hydrochloride (LH).
Lilang LI, Sha LIU, Donghai LI, Zhaoju ZHANG, Xiaosheng YANG, Juan YANG, Zhengrong ZHANG, Fufei ZENG, Yu WANG   +8 more
doaj   +1 more source

Autophagy and multidrug resistance in cancer

Chinese Journal of Cancer, 2017
Multidrug resistance (MDR) occurs frequently after long-term chemotherapy, resulting in refractory cancer and tumor recurrence. Therefore, combatting MDR is an important issue. Autophagy, a self-degradative system, universally arises during the treatment
Ying-Jie Li, Yu-He Lei, Nan Yao, Chen-Ran Wang, Nan Hu, Wen-Cai Ye, Dong-Mei Zhang, Zhe-Sheng Chen   +7 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Antiplasmodial Natural Products [PDF]

, 2011
Malaria is a human infectious disease that is caused by four species of Plasmodium. It is responsible for more than 1 million deaths per year. Natural products contain a great variety of chemical structures and have been screened for antiplasmodial ...
Lucia M. X. Lopes, Nogueira, Claudio R. [UNESP], Cláudio R. Nogueira, Nogueira, Claudio R., Lopes, Lucia Maria Xavier [UNESP], Lopes, Lucia Maria Xavier, Lopes, Lucia M. X.   +6 more
core   +1 more source

Natural products in endodontics

Saudi Medical Journal, 2018
Herbal remedies are used throughout the world, either in earlier or in recent times. The number of studies on this alternative therapeutic system increased in the last decades. In this paper, the relevant literature on the use of natural products in root canal therapy is revised from a MEDLINE database search.
Almadi, Ebtissam M., Almohaimede, Amal A.   +1 more
openaire   +2 more sources

Reduced Thioredoxin Regulates IL-1β Secretion via NLRP3 of IL-1β+ Alveolar Macrophages in COPD

Journal of Inflammation Research
Lueli Wang,1,* Rui Shi,1,* Zhaoliang Li,1 Ruoqiu Ma,1 Chongyu Wang,1,2 Changli Xu,1 Rong Guo,1 Chuang Xiao,1 Xiaohua Du,3 Weimin Yang1 1Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming ...
Wang L, Shi R, Li Z, Ma R, Wang C, Xu C, Guo R, Xiao C, Du X, Yang W   +9 more
doaj  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Twenty-five years of natural products research in NuBBE

, 2023
The richness of Brazilian biodiversity translates into a valuable collection of molecules with biological properties that range from ecological functions to pharmacological properties.
Queiroz, Suzana Aparecida Silva [UNESP], Rafael Vieira, Paula Carolina Pires Bueno, Cavalheiro, Alberto José [UNESP], Ian Castro-Gamboa, Tatiana Maria de Souza-Moreira, da Silva Bolzani, Vanderlan [UNESP], de Souza-Moreira, Tatiana Maria [UNESP], Felippe, Lidiane Gaspareto [UNESP], Helena Mannochio-Russo, Dulce Helena Siqueira Silva, Pilon, Alan Cesar [UNESP], Valli, Marilia, Andrea Nastri de Luca Batista, Silva, Dulce Helena Siqueira [UNESP], Rebeca Previate Medina, Medina, Rebeca Previate, Suzana Aparecida Silva Queiroz, Araujo, Angela Regina [UNESP], Alberto José Cavalheiro, Ana Letícia Pires dos Santos, Dutra, Luiz Antonio [UNESP], Pinto, Meri Emili Ferreira [UNESP], Bueno, Paula Carolina Pires, Alan Cesar Pilon, Luiz Antonio Dutra, Castro-Gamboa, Ian [UNESP], dos Santos, Ana Letícia Pires [UNESP], Vanderlan da Silva Bolzani, Furlan, Maysa [UNESP], de Luca Batista, Andrea Nastri, Meri Emili Ferreira Pinto, Marilia Valli, Mannochio-Russo, Helena [UNESP], Angela Regina Araujo, Maysa Furlan, Vieira, Rafael [UNESP], Lidiane Gaspareto Felippe   +37 more
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Effect of tobacco–radish rotation for different years on bacterial wilt and rhizosphere microbial communities

AMB Express
Tobacco bacterial wilt is a major limiting factor for tobacco production and development, and it is more likely to occur under perennial single cropping of tobacco. In recent years, the rotation of tobacco-radish has gradually become popular.
Yuhao Dai, Jixiu Li, Zhenzhen Wang, Shaoqi Yang, Qingju Xiao, Zipeng Gao, Fengjing Zhang, Chenran Zhao, Liang Yang, Shaopeng Chen, Wei Ding   +10 more
doaj   +1 more source