Results 111 to 120 of about 4,373,264 (365)

Products of abstract polytopes [PDF]

open access: yesarXiv, 2016
Given two convex polytopes, the join, the cartesian product and the direct sum of them are well understood. In this paper we extend these three kinds of products to abstract polytopes and introduce a new product, called the topological product, which also arises in a natural way. We show that these products have unique prime factorization theorems.
arxiv  

Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?

open access: yesMolecular Oncology, EarlyView.
 
Chen‐xi Li, Zhong‐cheng Gong
wiley   +1 more source

Synthesis and cytotoxic activity evaluation of novel imidazopyridine carbohydrazide derivatives

open access: yesBMC Chemistry
Two series of novel imidazo[1,2-a]pyridine-2-carbohydrazide derivatives have been designed, synthesized, and evaluated for cytotoxic activity. Target compounds were designed in two series: aryl hydrazone derivatives that were devoid of triazole moiety ...
Maryam Firouzi   +10 more
doaj   +1 more source

Metabolism of primaquine in normal human volunteers: investigation of phase I and phase II metabolites from plasma and urine using ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry

open access: yesMalaria Journal, 2018
Background Primaquine (PQ), an 8-aminoquinoline, is the only drug approved by the United States Food and Drug Administration for radical cure and prevention of relapse in Plasmodium vivax infections.
Bharathi Avula   +13 more
doaj   +1 more source

Blurring Boundaries: Toward the Collective Empathic Understanding of Product Requirements [PDF]

open access: yesarXiv, 2020
Within the agile paradigm, many software product companies create cross-functional product development teams that own their product or a defined set of product features. In contrast to development teams operating within a heavily-disciplined software development process, these product teams often require a deeper and, importantly, a collective ...
arxiv  

Super Natural II - a database of natural products [PDF]

open access: yes, 2014
Natural products play a significant role in drug discovery and development. Many topological pharmacophore patterns are common between natural products and commercial drugs.
Banerjee, Priyanka   +5 more
core   +6 more sources

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Derivation of Quantum Mechanics algebraic structure from invariance of the laws of Nature under system composition and Leibniz identity [PDF]

open access: yesarXiv, 2015
Products and tensor products are linked by a universal property. Imposing the invariance of the laws of Nature under tensor composition along with Leibniz identity determines quantum and classical mechanics algebraic structure through the interplay between products, coproducts, and the tensor product.
arxiv  

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

Glycerol 3-phosphate dehydrogenases (1 and 2) in cancer and other diseases

open access: yesExperimental and Molecular Medicine
The glycerol 3-phosphate shuttle (GPS) is composed of two different enzymes: cytosolic NAD+-linked glycerol 3-phosphate dehydrogenase 1 (GPD1) and mitochondrial FAD-linked glycerol 3-phosphate dehydrogenase 2 (GPD2).
Sehyun Oh   +5 more
doaj   +1 more source

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