Results 111 to 120 of about 4,373,264 (365)
Products of abstract polytopes [PDF]
Given two convex polytopes, the join, the cartesian product and the direct sum of them are well understood. In this paper we extend these three kinds of products to abstract polytopes and introduce a new product, called the topological product, which also arises in a natural way. We show that these products have unique prime factorization theorems.
arxiv
Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?
Chen‐xi Li, Zhong‐cheng Gong
wiley +1 more source
Synthesis and cytotoxic activity evaluation of novel imidazopyridine carbohydrazide derivatives
Two series of novel imidazo[1,2-a]pyridine-2-carbohydrazide derivatives have been designed, synthesized, and evaluated for cytotoxic activity. Target compounds were designed in two series: aryl hydrazone derivatives that were devoid of triazole moiety ...
Maryam Firouzi+10 more
doaj +1 more source
Background Primaquine (PQ), an 8-aminoquinoline, is the only drug approved by the United States Food and Drug Administration for radical cure and prevention of relapse in Plasmodium vivax infections.
Bharathi Avula+13 more
doaj +1 more source
Blurring Boundaries: Toward the Collective Empathic Understanding of Product Requirements [PDF]
Within the agile paradigm, many software product companies create cross-functional product development teams that own their product or a defined set of product features. In contrast to development teams operating within a heavily-disciplined software development process, these product teams often require a deeper and, importantly, a collective ...
arxiv
Super Natural II - a database of natural products [PDF]
Natural products play a significant role in drug discovery and development. Many topological pharmacophore patterns are common between natural products and commercial drugs.
Banerjee, Priyanka+5 more
core +6 more sources
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source
Derivation of Quantum Mechanics algebraic structure from invariance of the laws of Nature under system composition and Leibniz identity [PDF]
Products and tensor products are linked by a universal property. Imposing the invariance of the laws of Nature under tensor composition along with Leibniz identity determines quantum and classical mechanics algebraic structure through the interplay between products, coproducts, and the tensor product.
arxiv
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
Glycerol 3-phosphate dehydrogenases (1 and 2) in cancer and other diseases
The glycerol 3-phosphate shuttle (GPS) is composed of two different enzymes: cytosolic NAD+-linked glycerol 3-phosphate dehydrogenase 1 (GPD1) and mitochondrial FAD-linked glycerol 3-phosphate dehydrogenase 2 (GPD2).
Sehyun Oh+5 more
doaj +1 more source