Results 111 to 120 of about 4,327,329 (308)

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Potential Anticancer Activities of the Thai Traditional Medicinal Recipe Santakatpuakaln Against Colorectal Cancer Cell Lines

open access: yesAdvances in Pharmacological and Pharmaceutical Sciences
Traditional Thai herbal medicine has been used for centuries to treat various diseases, including cancer. One notable formulation, Santakatpuakaln (STK), has been employed to manage cancers, particularly of the gastrointestinal (GI) tract, such as liver ...
Worrakanya Narakornwit   +4 more
doaj   +1 more source

Compound basis arising from the basic $A^{(1)}_{1}$-module

open access: yes, 2008
A new basis for the polynomial ring of infinitely many variables is constructed which consists of products of Schur functions and Q-functions.
A. Lascoux   +12 more
core   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

open access: yesFEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner   +6 more
wiley   +1 more source

An Overview of Marketing of Ghana Natural Products [PDF]

open access: yes
The study finds strong correlations between natural products business performance and the impeding factors. The impediments include access to finance and markets, lack of herbal market information especially relating to external markets.
Acquaye, Dan   +8 more
core   +1 more source

Wedge modules for two-parameter quantum groups

open access: yes, 2013
The Yang-Baxterization R(z) of the trigonometric R-matrix is computed for the two-parameter quantum affine algebra of type A. Using the fusion procedure we construct all fundamental representations of the quantum algebra as wedge products of the natural ...
Jing, Naihuan, Liu, Ming, Zhang, Lili
core   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

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