Results 51 to 60 of about 9,605,578 (343)
Malaria Journal, 2019 Background The activity and haemolytic toxicity associated with primaquine has been linked to its reactive metabolites. The reactive metabolites are thought to be primarily formed through the action of cytochrome P450-mediated pathways.
Pius S. Fasinu +9 more
doaj +1 more source
Natural products as sources of new drugs over the last 25 years.
Journal of Natural Products, 2007 This review is an updated and expanded version of two prior reviews that were published in this journal in 1997 and 2003. In the case of all approved agents the time frame has been extended to include the 251/2 years from 01/1981 to 06/2006 for all ...
D. Newman, G. Cragg
semanticscholar +1 more source
Natural product fragment combination to performance-diverse pseudo-natural products
Nature Communications, 2021 Natural product structure and fragment-based compound development inspire pseudo-natural product design through different combinations of a given natural product fragment set to compound classes expected to be chemically and biologically diverse.
Michael Grigalunas +12 more
semanticscholar +1 more source
ASEAN Journal on Science and Technology for Development, 2017 A novel bibenzopyran named bimalloapelta (1) was synthesized relying on electrooxydation of malloapelta B by cyclic voltammetry in acetonitril adding LiClO4 0.1 M as supporting electrolyte.
Phan Thi Binh +5 more
doaj +1 more source
Techniques for extraction and isolation of natural products: a comprehensive review
Chinese Medicine, 2018 Natural medicines were the only option for the prevention and treatment of human diseases for thousands of years. Natural products are important sources for drug development.
Qing-Wen Zhang, Ligen Lin, W. Ye
semanticscholar +1 more source
A review of sustainable and intensified techniques for extraction of food and natural products
Green Chemistry, 2020 This review presents innovative extraction techniques and their role in promoting sustainable ingredients for the food, cosmetic and pharmaceutical industries.
F. Chemat +9 more
semanticscholar +1 more source
Natural Product Reports, 2023 In natural products, a low optical purity is not generally associated with a sloppy enzymatic activity, but rather with the co-expression of antipodal enzymes/directing proteins or, alternatively, with erosion by enzymatic or spontaneous reactions.
Mazzotta, Sarah +5 more
openaire +2 more sources
Plant-Derived Natural Products: A Source for Drug Discovery and Development
Drugs and Drug CandidatesFor thousands of years, nature has been a source of medical substances, and an astounding numeral of contemporary remedies have been identified from natural origins.
N. Chaachouay, L. Zidane
semanticscholar +1 more source
Antimicrobial Natural Products
Antibiotics, 2022 Infectious diseases, resulting from microbial pathogens, are one of the major causes of morbidity and mortality worldwide [...]
openaire +3 more sources
The unpredictably eruptive dynamics of spruce budworm populations in eastern Canada
Population Ecology, EarlyView.We examine historical population data for spruce budworm from several locations through the period 1930–1997, and use density‐dependent recruitment curves to test whether the pattern of population growth over time is more consistent with Royama's (1984; Ecological Monographs 54:429–462) linear R(t) model of harmonic oscillation at Green River New ...
Barry J. Cooke, Jacques Régnière
wiley +1 more source