Results 51 to 60 of about 220,082 (245)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Comparing natural regeneration of Norway spruce Picea abies (L.) Karst. in the Kaszuby Lake District and in the other regions of northern Poland

Leśne Prace Badawcze, 2017
The paper investigates the biometric characteristics natural Norway spruce (Picea abies (L.) Karst.) regeneration in the Kaszuby Lake District, which is beyond the acknowledged Norway spruce range, with the natural regeneration in the Augustów Forest ...
Szydlarski Marcin, Modrzyński Jerzy, Stopiński Mateusz, Majewski Michał, Maras Krzysztof   +4 more
doaj   +1 more source

Effects of gap size on natural regeneration and micro-environmental soil conditions in European beech (Fagus sylvatica L.) and Norway spruce (Picea abies (L.) Karst) dominated mixed forest

Plant, Soil and Environment, 2020
The study focused on the effects of gap size on natural regeneration of European beech (Fagus sylvatica L.) and Norway spruce (Picea abies L.) and micro-environmental soil conditions in gaps of different sizes under temperate mixed forest in the Czech ...
Maame Esi Hammond, Radek Pokorný
doaj   +1 more source

Cell unit-inspired natural nano-based biomaterials as versatile building blocks for bone/cartilage regeneration

Journal of Nanobiotechnology, 2023
The regeneration of weight-bearing bone defects and critical-sized cartilage defects remains a significant challenge. A wide range of nano-biomaterials are available for the treatment of bone/cartilage defects.
Fuxiao Wang, Zhengrong Gu, Zhifeng Yin, Wencai Zhang, Long Bai, Jiacan Su   +5 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Economics of Naturally Regenerating, Heterogeneous Forests [PDF]

Journal of the Association of Environmental and Resource Economists, 2015
AbstractAn economic model for naturally regenerating, heterogeneous forests is specified to yield both clear-cuts and continuous cover forestry endogenously. The model includes nonconvexities and any number of state variables but is, in its simplest form, a one-state variable problem.
openaire   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Study of the recovery soil physical properties and establishment of natural regeneration in skid trails (case study: Nav-e Asalem forests) [PDF]

مجله جنگل ایران, 2012
Soil properties affected by passing the machines in skid trails and establishment of natural regeneration and herbaceous palnts in these routes after the harvesting operation could be a suitable opportunity to study the reaction of different plant ...
doaj  

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source