Results 61 to 70 of about 5,415,293 (346)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Blood mitochondrial metabolism predicts flight performance without lasting effects of early-life thyroid hormones

iScience
Summary: Early-life conditions can shape adult phenotypes by influencing processes linked to energetic homeostasis. Thyroid hormones (THs) enhance mitochondrial electron transport chain capacity (ETS) in fledglings, but whether this effect is permanent ...
Marlene Oefele, Michaela Hau, Suvi Ruuskanen, Stefania Casagrande   +3 more
doaj   +1 more source

The Bologna agreement is not suitable for medical education : a German view [PDF]

, 2010
Central elements of the Bologna declaration have been implemented in a huge variety of curricula in humanities, social sciences, natural sciences and engineering sciences at German universities. Overall the results have been nothing less than disastrous.
Pfeilschifter, Josef Martin (Prof. Dr.)
core  

A coupled hydrology-biogeochemistry model to simulate dissolved organic carbon exports from a permafrost influenced catchment [PDF]

, 2015
Funded by Natural Environment Research Council. Grant Number: NE/K000268/1 Natural Sciences and Engineering Research Council of CanadaPeer reviewedPublisher ...
Abdalla, Balcarczyk, Beven, Beven, Beven, Birkel, Bishop, Boyer, Carey, Carey, Carey, Carey, Cole, Cory, Criss, Dick, Dornes, Dye, Eddelbuettel, Eddelbuettel, Finlay, Frey, Futter, Gray, Guo, Guo, Guo, Gupta, Hamilton, Hamilton, Holmes, Holmes, Hottelet, Hugelius, Jutras, Kawahigashi, Kicklighter, Koch, Konz, Krause, Laudon, Lenton, Lewkowicz, Lindström, Lyon, Mann, McCartney, McClelland, McGuire, McNamara, Michalzik, Neff, O'Donnell, Oelke, Petrone, Prokushkin, Quinton, Quinton, Quinton, Raymond, Schoups, Schuur, Smith, Smith, Striegl, Tank, Tetzlaff, Thornthwaite, Tjoelker, Van Griensven, Wickland, Zambrano-Bigiarini, Zou   +72 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Paradigm shift in determining Neoproterozoic atmospheric oxygen [PDF]

, 2016
ACKNOWLEDGMENTS We thank the Geological Survey of Australia for permission to sample the Empress 1A and Lancer 1 cores, the Natural Sciences and Engineering Research Council of Canada for financial support (grant #7961–15) of U.
Benison, Kathleen, Blamey, Nigel J. F., Brand, Uwe, Lécuyer, Christophe, Meng, Fanwei, Ni, Pei, Parnell, John, Spear, Natalie   +7 more
core   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Learning, economies of scale, and knowledge gap effects on power generation technology cost improvements

iScience
Summary: Cost reductions are essential for accelerating clean technology deployment. Because multiple factors influence costs, traditional one-factor learning models, solely relying on cumulative installed capacity as an explanatory variable, may ...
Yoga W. Pratama, Matthew J. Gidden, Jenna Greene, Andrew Zaiser, Gregory Nemet, Keywan Riahi   +5 more
doaj   +1 more source

Creation's Persistent Voice: Critiquing the Secondary Status [PDF]

, 2012
Christianity struggles with the concept that nature/creation is truly revelatory of God, and not merely confirmatory of theological conclusions derived from special revelation or deduced from rational reflection.
Bouma, Rolf
core   +1 more source

Deterministic chaos theory and forecasting in Social Sciences. Contribution to the discussion [PDF]

, 2018
Forecasting social phenomena may be hampered in many ways. This is because in nature of these phenomena lies strong and multilateral connection with other social phenomena; but not only – also physical and biological (natural) ones.
Donaj, Łukasz
core   +2 more sources