Results 41 to 50 of about 7,095,217 (351)
The Selective Maintenance of Allelic Variation Under Generalized Dominance
G3: Genes, Genomes, Genetics, 2016 Simple models of viability selection acting on variation at a single diploid locus only maintain multiple alleles for very restricted sets of fitnesses. Most of these models assume that fitnesses are independent, even if the genotypes share alleles. Here,
Hamish G. Spencer, Cuilodair Mitchell
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Natural Selection Towards Wild-Type in Composite Cross Populations of Winter Wheat
Frontiers in Plant Science, 2020 Most of our crops are grown in monoculture with single genotypes grown over wide acreage. An alternative approach, where segregating populations are used as crops, is an exciting possibility, but outcomes of natural selection upon this type of crop are ...
Samuel Knapp +9 more
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Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Microevolution, speciation and macroevolution in rhizobia: Genomic mechanisms and selective patterns
Frontiers in Plant Science, 2022 Nodule bacteria (rhizobia), N2-fixing symbionts of leguminous plants, represent an excellent model to study the fundamental issues of evolutionary biology, including the tradeoff between microevolution, speciation, and macroevolution, which remains ...
Nikolay A. Provorov +7 more
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The asymptotic nature of natural selection [PDF]
Transactions of the Edinburgh Geological Society, 1883 I suppose all the members present understand what is meant by the term ‶asymptote″ in mathematics. The best example of it is found in the case of the curve known as the ‶hyperbola,″ where two straight lines may be drawn such that the two branches of the curve continually approach but never touch them.
openaire +3 more sources
What is adaptation by natural selection? Perspectives of an experimental microbiologist
PLoS Genetics, 2017 Ever since Darwin, the role of natural selection in shaping the morphological, physiological, and behavioral adaptations of animals and plants across generations has been central to understanding life and its diversity.
R. Lenski
semanticscholar +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Natural Selection and Morality [PDF]
Ideas y Valores, 2006 Resumen:En este ensayo abordo los intentos, relativamente recientes, de dar una explicación de la moralidad como adaptación por selección natural. Mi exposición tiene una introducción y cuatro partes: en la primera explico en qué consiste la paradoja del
Alejandro Rosas
doaj
Genetic evidence for natural selection in humans in the contemporary United States
Proceedings of the National Academy of Sciences of the United States of America, 2016 Significance I leverage recent advances in molecular genetics to test directly whether genetic variants associated with a number of phenotypes have been under natural selection in the contemporary United States. My finding that natural selection has been
J. Beauchamp
semanticscholar +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source