Results 41 to 50 of about 5,918,329 (258)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Mitochondrial DNA. Part B. Resources, 2021 Dolichandrone spathacea(L. F.) K. Schum. is an excellent tree species for coastal protection forests. In this study, the complete chloroplast genome sequence of D. spathacea was obtained through high-throughput sequencing.
Ting Yu +8 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
What can we do for nature? A systematic research approach to pro-nature conservation behaviours [PDF]
, 2021 Nature is in trouble. The current levels of anthropogenic biodiversity loss have been classed by experts as a mass extinction. This is likely to have grave consequences for humanity.
Barbett, L.
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Conservation Businesses and Conservation Planning in a Biological Diversity Hotspot [PDF]
, 2013 The allocation of land to biological diversity conservation competes with other land uses and the needs of society for development, food, and extraction of natural resources.
MacMillan, Douglas C.
core +1 more source
Scientific ReportsWild Forest musk deer (FMD) has been declining due to continuing poaching and habitat loss. Although captive breeding has increased population numbers, maintaining genetic diversity in these farmed populations has become increasingly urgent and ...
Xianna Lan +12 more
doaj +1 more source
Three new species of Picipes (Polyporales, Basidiomycota) from China [PDF]
MycoKeysThree new wood-inhabiting fungi viz. Picipes abieticola, P. brevisporus and P. sinodictyopus spp. nov. are proposed, based on a combination of morphological features and molecular evidence.
Kai-Yue Luo +5 more
doaj +3 more sources
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
, 2013 Seed planting, although a simple process, it is only efficient when done properly!
Khalil, Antoine +4 more
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