Results 61 to 70 of about 1,733,399 (308)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Organic farming and biodiversity – how to create a viable farm business including conservation issues [PDF]
, 2008 The extension of organic farming (OF), the increasing recognition of the advantages for improving agro-biodiversity, and the fact that the protection of nature and natural species cannot be taken for granted, has resulted in several interdisciplinary ...
Fuchs, Sarah, Stein-Bachinger, Dr. Karin
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Scientific ReportsFreshwater mussels (Unionidae) depend on specific fish hosts to complete their life cycle. Glochidia, their parasitic larvae, must attach to the gills or fins of suitable fish species to metamorphose.
Jacek Dołęga +5 more
doaj +1 more source
BMC Genomics, 2019 Background Under caged conditions, birds are affected more severely by environmental stressors such as dietary structure, activity space, human disturbances, and pathogens, which may be reflected in the gene expression in peripheral blood or other ...
Yu Wang +4 more
doaj +1 more source
Biodiversity As An Ecological Safety Condition. The European Dimension [PDF]
, 2015 The main purpose of the paper is to indicate the theoretical bases of biodiversity protection from the perspective of the natural and economic sciences, and to describe the diversity of biodiversity protection levels in the EU states.
Rzeńca, Agnieszka
core +2 more sources
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Beyond Philanthropy: Community Nature-based Enterprises as a Basis for Wildlife Conservation [PDF]
, 2012 This paper shows how communities can be vehicles for nature conservation through community ...
Munira Anyonge-Bashir, Paul Udoto
core +1 more source
Conserving tropical biodiversity via market forces and spatial targeting [PDF]
, 2015 The recent report from the Secretariat of the Convention on Biological Diversity [(2010) Global Biodiversity Outlook 3] acknowledges that ongoing biodiversity loss necessitates swift, radical action.
Badura, Tomas +8 more
core +2 more sources
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source