Results 101 to 110 of about 27,017 (217)

Emotional dimensions of nurses’ daily work in newborn units in Kenya: a qualitative study

BMC Public Health
Background The importance of developing and supporting emotional well-being among all frontline health system staff, including those in leadership positions, is increasingly recognized as essential to health system resilience and patient outcomes. Nurses
Dyuti Sen, Mwanamvua Boga, Peris Musitia, Dorothy Oluoch, Yasangra Adeniji, Nancy Odinga, Caroline Waithira, Gloria Ngaiza, Sebastian Fuller, Jacinta Nzinga, Mike English, Sassy Molyneux   +11 more
doaj   +1 more source

Tackling the unyielding: testing two novel approaches against NDM-producing Enterobacterales and Pseudomonas aeruginosa isolates collected in India

Microbiology Spectrum
The in vitro activity of two novel antibiotics with different modes of action, (i) siderophore cefiderocol and (ii) β-lactam-enhancer mechanism-based cefepime/zidebactam, was tested against New Delhi Metallo-β-lactamase (NDM)-producing Enterobacterales ...
Yamuna Devi Bakthavatchalam, Bijayini Behera, Anand Shah, Purva Mathur, Raja Ray, Bashir Ahmed Fomda, Kamini Walia, Balaji Veeraraghavan   +7 more
doaj   +1 more source

Embelin Restores Carbapenem Efficacy against NDM-1-Positive Pathogens

, 2018
The emergence and spread of carbapenemase in Gram-negative pathogens poses an enormous threat to global public health. New Delhi metallo-β-lactamase-1 (NDM-1) inactivates nearly every class of β-lactam antibiotics, including carbapenem; however, there is
Zhan Li, Peng Zhou, Hui Wang, Jie Huang, Nian-Zhi Ning, Xiong Liu, Lihong Hu, Tao Li, Fanghong Chen, Jian Huang   +9 more
core   +1 more source

SDS-PAGE (5 to 12%) gels of NDM-1 purification.

, 2013
Lane 1, Takara protein molecular weight marker; lane 2, boiled cell fraction of E. coli.BL21(DE3) containing pET30a-NDM-1 before induction; lane 3, boiled cell fraction of E. coli. BL21(DE3) containing pET30a-NDM-1 after a 14 h induction with 0.1 mM IPTG
Yongliang Fang (587682), Bingzheng Shen (587681), Yan Yu (56143), Yun Shi (172065), Heng Zheng (447307), Xin Cao (288308), Hui Chen (28597), Jiao Chen (447306), Xingzhen Lao (447305)   +8 more
core   +1 more source

Genomic Insights into Carbapenem-Resistant Organisms Producing New Delhi Metallo-β-Lactamase in Live Poultry Markets

Microorganisms
New Delhi metallo-β-lactamase (NDM) is an enzyme that can degrade a wide range of β-lactam antibiotics. The widespread dissemination of the blaNDM gene, which encodes NDM, in animal-derived settings poses a threat to public health security.
Xueqiang Xin, Yi Yin, Jiayong Kong, Mianzhi Wang, Zhiqiang Wang, Ruichao Li   +5 more
doaj   +1 more source

Emergence of Various NDM-Type-Metallo-β-Lactamase-Producing Escherichia coli Clinical Isolates in Nepal

, 2017
Of 250 clinical isolates of Escherichia coli obtained in Nepal, 38 were carbapenem resistant, with MICs of imipenem or meropenem of ≥4 μg/ml. All 38 isolates harbored the following bla NDM s:
Bharat Mani Pokhrel, Kayo Shimada, Teruo Kirikae, Tatsuya Tada, Shovita Shrestha, Hiroshi Ohara, Jeevan B. Sherchand, Basudha Shrestha   +7 more
core   +1 more source

Coomassie blue stained 12% SDS-PAGE of purified NDM-1.

, 2013
The highly purified and soluble NDM-1 is shown. The molecular weight of NDM-1 is approximately 28 kDa.
Sen Luo (402165), Dehui Wang (402167), Xiang Li (114679), Qin Wang (109812), Hui Wang (30400), Fanghong Chen (402164), Zhan Li (402168), Tao Li (86810), Huali Fang (402166), Xiaojun Hou (402169)   +9 more
core   +1 more source

Morin combined with meropenem is a potent inhibitor of NDM-1 against NDM-1-producing E. coli

Scientific Reports
Some β-lactam antibiotics are hydrolyzed by the enzyme New Delhi metallo-β-lactamase 1 (NDM-1), increasing antibiotic resistance and posing a significant threat to public health. Thus, there is an urgent need to develop and use potent inhibitors of NDM-1 and other β-lactamases.
Ren, Qinghai, Zhang, Boyang, Wang, Minge, Wang, Tongtong, Zhang, Wei, Du, Li, Yu, Meng, Li, Yubao, Li, Xiaoting   +8 more
openaire   +2 more sources

Molecular models of NDM-1 and its complex with antibiotics.

, 2013
A. The active site of NDM-1 with two zinc ions and the coordinating residues. B. The comparison of the two loops in NDM-1 and VIM-2. The loops and key residues in NDM-1 are colored in gray, while in VIM-2 colored in green. C.
Hualiang Jiang (19452), Lianchun Li (166558), Xu Shen (66684), Yuanyuan Wang (20181), Cai Guang-Yang (345537), Limin Chen (90676), Hong Liu (50694), Cheng Luo (48047), Lefu Lan (345536), Kaixian Chen (19449), Mingyue Zheng (180908), Zhongjie Liang (163372), Xiangqian Kong (166573), Keqin Kathy Li (202911), Yao Hong (345535)   +14 more
core   +1 more source

Two copies of bla (NDM-1) gene are present in NDM-1 producing Pseudomonas aeruginosa isolates from Serbia

, 2013
New Delhi metallo-beta-lactamase producing Pseudomonas aeruginosa isolates are of special interest since P. aeruginosa is a major cause of nosocomial infections, the treatment of which could now be jeopardized, especially in developing countries.
Filipić, Brankica, Jovčić, Branko, Kojić, Milan, Lepsanović, Zorica, Begović, Jelena   +4 more
core   +1 more source