Results 101 to 110 of about 24,350 (217)

ORFs in NDM-1 composite transposon.

, 2013
ORFs in NDM-1 composite transposon.
Kunikazu Yamane (343522), Mari Matsui (343521), Fumihiko Takeuchi (118220), Yoshichika Arakawa (183806), Tsuyoshi Sekizuka (249989), Makoto Ohnishi (82158), Akira Hishinuma (343523), Makoto Kuroda (249974)   +7 more
core   +1 more source

Mechanistic and Spectroscopic Studies of Metallo-β-lactamase NDM-1

, 2016
In an effort to biochemically characterize metallo-β-lactamase NDM-1, we cloned, overexpressed, purified, and characterized several maltose binding protein (MBP)–NDM-1 fusion proteins with different N-termini (full-length, Δ6, Δ21, and Δ36).
Michael W. Crowder (1319943), Alyssa M. Hetrick (2085961), Hao Yang (328526), Timothy K. Richmond (2085958), Mahesh Aitha (1319940), David L. Tierney (1314624)   +5 more
core   +1 more source

Embelin Restores Carbapenem Efficacy against NDM-1-Positive Pathogens

, 2018
The emergence and spread of carbapenemase in Gram-negative pathogens poses an enormous threat to global public health. New Delhi metallo-β-lactamase-1 (NDM-1) inactivates nearly every class of β-lactam antibiotics, including carbapenem; however, there is
Zhan Li, Peng Zhou, Hui Wang, Jie Huang, Nian-Zhi Ning, Xiong Liu, Lihong Hu, Tao Li, Fanghong Chen, Jian Huang   +9 more
core   +1 more source

Genomic characterization of plasmids harboring bla_NDM-1, bla_NDM-5, and bla_NDM-7 carbapenemase alleles in clinical Klebsiella pneumoniae in Pakistan

Klebsiella pneumoniae is notorious for causing healthcare-associated infections, which become more complicated by the acquisition of bla NDM genes via mobile genetic elements.
Rizwan, Muhammad, Qamar, Muhammad Usman, Andrey, Diego Olivier, Jabeen, Kokab, Sierra, Roberto, Rashid, Ayesha, Dar, Yumna Fatima   +6 more
core   +1 more source

Coomassie blue stained 12% SDS-PAGE of purified NDM-1.

, 2013
The highly purified and soluble NDM-1 is shown. The molecular weight of NDM-1 is approximately 28 kDa.
Sen Luo (402165), Dehui Wang (402167), Xiang Li (114679), Qin Wang (109812), Hui Wang (30400), Fanghong Chen (402164), Zhan Li (402168), Tao Li (86810), Huali Fang (402166), Xiaojun Hou (402169)   +9 more
core   +1 more source

Emergence of Various NDM-Type-Metallo-β-Lactamase-Producing Escherichia coli Clinical Isolates in Nepal

, 2017
Of 250 clinical isolates of Escherichia coli obtained in Nepal, 38 were carbapenem resistant, with MICs of imipenem or meropenem of ≥4 μg/ml. All 38 isolates harbored the following bla NDM s:
Bharat Mani Pokhrel, Kayo Shimada, Teruo Kirikae, Tatsuya Tada, Shovita Shrestha, Hiroshi Ohara, Jeevan B. Sherchand, Basudha Shrestha   +7 more
core   +1 more source

Morin combined with meropenem is a potent inhibitor of NDM-1 against NDM-1-producing E. coli

Scientific Reports
Some β-lactam antibiotics are hydrolyzed by the enzyme New Delhi metallo-β-lactamase 1 (NDM-1), increasing antibiotic resistance and posing a significant threat to public health. Thus, there is an urgent need to develop and use potent inhibitors of NDM-1 and other β-lactamases.
Ren, Qinghai, Zhang, Boyang, Wang, Minge, Wang, Tongtong, Zhang, Wei, Du, Li, Yu, Meng, Li, Yubao, Li, Xiaoting   +8 more
openaire   +2 more sources

Molecular models of NDM-1 and its complex with antibiotics.

, 2013
A. The active site of NDM-1 with two zinc ions and the coordinating residues. B. The comparison of the two loops in NDM-1 and VIM-2. The loops and key residues in NDM-1 are colored in gray, while in VIM-2 colored in green. C.
Hualiang Jiang (19452), Lianchun Li (166558), Xu Shen (66684), Yuanyuan Wang (20181), Cai Guang-Yang (345537), Limin Chen (90676), Hong Liu (50694), Cheng Luo (48047), Lefu Lan (345536), Kaixian Chen (19449), Mingyue Zheng (180908), Zhongjie Liang (163372), Xiangqian Kong (166573), Keqin Kathy Li (202911), Yao Hong (345535)   +14 more
core   +1 more source

SDS-PAGE (5 to 12%) gels of NDM-1 purification.

, 2013
Lane 1, Takara protein molecular weight marker; lane 2, boiled cell fraction of E. coli.BL21(DE3) containing pET30a-NDM-1 before induction; lane 3, boiled cell fraction of E. coli. BL21(DE3) containing pET30a-NDM-1 after a 14 h induction with 0.1 mM IPTG
Yongliang Fang (587682), Bingzheng Shen (587681), Yan Yu (56143), Yun Shi (172065), Heng Zheng (447307), Xin Cao (288308), Hui Chen (28597), Jiao Chen (447306), Xingzhen Lao (447305)   +8 more
core   +1 more source

Tackling the unyielding: testing two novel approaches against NDM-producing Enterobacterales and Pseudomonas aeruginosa isolates collected in India

Microbiology Spectrum
The in vitro activity of two novel antibiotics with different modes of action, (i) siderophore cefiderocol and (ii) β-lactam-enhancer mechanism-based cefepime/zidebactam, was tested against New Delhi Metallo-β-lactamase (NDM)-producing Enterobacterales ...
Yamuna Devi Bakthavatchalam, Bijayini Behera, Anand Shah, Purva Mathur, Raja Ray, Bashir Ahmed Fomda, Kamini Walia, Balaji Veeraraghavan   +7 more
doaj   +1 more source