Results 11 to 20 of about 53,718 (156)

Optimization and evaluation of transdermal delivery system for nebivolol hydrochloride [PDF]

Journal of Applied Pharmaceutical Research
Background: Nebivolol hydrochloride, a β1-receptor antagonist known for its antihypertensive properties, boasts a plasma half-life of 10 hours and an oral bioavailability of 12%.
P V Shelke, Punit R Rachh, S D Mankar, Prasad L. Gorde   +3 more
doaj   +4 more sources

(S,S,S,S)-Nebivolol hydrochloride hemihydrate [PDF]

Acta Crystallographica Section E, 2012
The asymmetric unit of the title hydrated salt, C22H26F2NO4+·Cl−·0.5H2O, consists of an (S,S,S,S)-nebivolol {nebivol = bis[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl]ammonium} cation, a chloride anion and a ...
Yoann Rousselin, Amelie Bruel, Alexandre Clavel   +2 more
doaj   +4 more sources

DESIGN AND EVALUATION OF LIQUISOLID COMPACTS OF NEBIVOLOL HYDROCHLORIDE [PDF]

International Journal of Applied Pharmaceutics, 2022
Objective: The aim of this study was to investigate the potential of a liquisolid system to improve the dissolution rate and the bioavailability of nebivolol hydrochloride. Methods: Solubility of nebivolol was determined in different nonvolatile solvents to finalize the best nonvolatile vehicle having maximum solubility.
RAMYA SRI SURA, CVS SUBRAHMANYAM, SHYAM SUNDER RACHAMALLA   +2 more
core   +3 more sources

Formulation and Evaluation of Bilayer Matrix Tablets of Nebivolol Hydrochloride and Valsartan

Journal of Drug Delivery and Therapeutics, 2019
The present study is an attempt to develop bilayer matrix tablets of Nebivolol Hydrochloride and Valsartan with immediate release for Nebivolol Hydrochloride and sustained release for Valsartan. Superdisintegrants such as sodium starch glycolate and Crosscarmellose sodium were evaluated for immediate release of Nebivolol Hydrochloride and polymers HPMC
C. Emmanuel, D. Satyavati, L. Srinivas, Selvi Arunkumar   +3 more
openaire   +3 more sources

Optimization and evaluation of nebivolol hydrochloride loaded transferosomes using Box-Behnken experimental design [PDF]

Journal of Applied Pharmaceutical Research
Background: This study optimizes and evaluates transferosomes containing Nebivolol Hydrochloride to enhance the drug's bioavailability and therapeutic efficacy.
P V Shelke, Punit R Rachh, Someshwar Mankar, Saurin Amin, Deepak Jain   +4 more
doaj   +2 more sources

Advanced eco-friendly spectrophotometric analysis for Nebivolol, Valsartan, and related impurity with comprehensive environmental impact assessment [PDF]

Scientific Reports
At present, one of the main priorities for analysts is creating more sustainable and environmentally friendly methods for pharmaceutical analysis. In this context, three innovative spectrophotometric techniques, using tri-colored (green, blue, and white),
Abdallah M. Hamdy, Magda M. El Henawee, Hisham Hashem, Esraa M. Meselhy, Hany Ibrahim   +4 more
doaj   +2 more sources

RETRACTED: Elsherif et al. Investigation of the Potential of Nebivolol Hydrochloride-Loaded Chitosomal Systems for Tissue Regeneration: In Vitro Characterization and In Vivo Assessment. Pharmaceutics 2021, 13, 700

Pharmaceutics
The journal retracts the article “Investigation of the Potential of Nebivolol Hydrochloride-Loaded Chitosomal Systems for Tissue Regeneration: In Vitro Characterization and In Vivo Assessment” [...]
Noha Ibrahim Elsherif, Abdulaziz Mohsen Al-Mahallawi, Abdelfattah Ahmed Abdelkhalek, Rehab Nabil Shamma   +3 more
doaj   +2 more sources

Nebivolol Polymeric Nanoparticles-Loaded In Situ Gel for Effective Treatment of Glaucoma: Optimization, Physicochemical Characterization, and Pharmacokinetic and Pharmacodynamic Evaluation [PDF]

Nanomaterials
Nebivolol hydrochloride (NEB), a 3rd-generation beta-blocker, was recently explored in managing open-angle glaucoma due to its mechanism of action involving nitric oxide release for the vasodilation.
Pradeep Singh Rawat, Punna Rao Ravi, Mohammed Shareef Khan, Radhika Rajiv Mahajan, Łukasz Szeleszczuk   +4 more
doaj   +2 more sources

Quantitative determination of Nebivolol Hydrochloride and Rosuvastatin Calcium in laboratory prepared mixture by robust, high-performance liquid chromatographic method

Discover Chemistry
A robust and eco-friendly high-performance liquid chromatographic (HPLC) method has been developed and validated to quantify Nebivolol Hydrochloride and Rosuvastatin Calcium in a laboratory-prepared mixture, following ICH guidelines. Utilizing a Shimpack
Sandeep Bolla, Narender Boggula
exaly   +2 more sources

Stability-Indicating TLC-Densitometric Determination of Nebivolol Hydrochloride in Bulk and Pharmaceutical Dosage Form [PDF]

Journal of Chromatographic Science, 2010
A simple, selective, precise, and stability-indicating high-performance thin-layer chromatographic (HPTLC) method for densitometric determination of nebivolol hydrochloride both as a bulk drug and in formulation was developed and validated as per the international conference on harmonization guidelines (ICH).
Sanjay Surana, Atul A Shirkhedkar
exaly   +3 more sources