Results 21 to 30 of about 53,718 (156)

Analytical methods for nebivolol quantification in pharmaceutical formulations and biological matrices: a comprehensive review

Discover Chemistry
Nebivolol, a beta-blocker commonly prescribed for the treatment of hypertension and heart failure, functions by decelerating heart rate and promoting vasodilation, thereby enhancing blood flow and reducing blood pressure.
Kurdo A. Abdullah, Aryan Fathulla Qader, Rebaz Anwar Omer, Rebaz Obaid Kareem, Musher Ismael Salih   +4 more
doaj   +2 more sources

Photochemical Deracemization of Chromanes and its Application to the Synthesis of Enantiopure Bioactive Compounds. [PDF]

Angew Chem Int Ed Engl
Various substituted chromane‐2‐carboxamides were successfully deracemized by employing a chiral benzophenone (BP, 10 mol%) as photocatalyst and an achiral thiol as additive (20 mol%). The method was applied to the concise enantioselective synthesis of five active pharmaceutical ingredients.
Ghosh B, Iglhaut M, Babushkina D, Pauls M, Bannwarth C, Bach T.   +5 more
europepmc   +3 more sources

Splicing factor TRA2A contributes to esophageal cancer progression via a noncanonical role in lncRNA m⁶ A methylation. [PDF]

Cancer Sci, 2023
In normal conditions, TRA2A recruits a set of RNA methylation‐associated proteins, such as RBMX and KIAA1429, to modulate lncRNA MALAT1 methylation and stability. In esophageal cancers, TRA2A is upregulated and promotes oncogenic lncRNA MALAT1 methylation and cellular stability, thereby influencing proliferation capability and tumor formation ...
Bei M, Hao S, Lin K, Chen Q, Cai Y, Zhao X, Jiang L, Lin L, Dong G, Xu J.   +9 more
europepmc   +2 more sources

Simultaneous Estimation of Nebivolol Hydrochloride and Hydrochlorothiazide in Tablets

International Journal of Pharmaceutical Research and Allied Sciences, 2022
exaly   +2 more sources

DEVELOPMENT OF RP-HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF NEBIVOLOL HYDROCHLORIDE, VALSARTAN AND HYDROCHLOROTHIAZIDE IN CO-ADMINISTRATED ANTIHYPERTENSIVE AGENTS AND HUMAN PLASMA [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 2023
Reversed phase high performance liquid chromatography combined with photodiode array (HPLC-PDA) detector method was developed for simultaneous determination of two binary antihypertensive combinations; either Nebivolol (NEB) with Hydrochlorothiazide (HCZ)
M. Rizk, Maha Abou El‐Alamin, Shereen Mowaka, Mariam Mohamed   +3 more
doaj   +1 more source

Development of a capillary electrophoresis method for quantification of orally disintegrating tablets of nebivolol hydrochloride

, 2023
Com o objetivo de quantificar o cloridrato de nebivolol em comprimidos de desintegração oral, no presente trabalho foi desenvolvido um método de eletroforese capilar. A gestão do conhecimento foi efetuada através da realização de experiências preliminares de exploração que incluíram a seleção de um ponto de partida adequado para a milimolaridade e o pH
Esteves, Catarina Vasco Gonçalves
core   +4 more sources

The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

British Journal of Pharmacology, Volume 180, Issue S2, Page S23-S144, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander, Arthur Christopoulos, Anthony P. Davenport, Eamonn Kelly, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Jamie A. Davies, Maria Pia Abbracchio, George Abraham, Alexander Agoulnik, Wayne Alexander, Khaled Al‐hosaini, Magnus Bäck, Jillian G. Baker, Nicholas M. Barnes, Ross Bathgate, Jean‐Martin Beaulieu, Annette G. Beck‐Sickinger, Maik Behrens, Kenneth E. Bernstein, Bernhard Bettler, Nigel J. M. Birdsall, Victoria Blaho, Francois Boulay, Corinne Bousquet, Hans Bräuner‐Osborne, Geoffrey Burnstock, Girolamo Caló, Justo P. Castaño, Kevin J. Catt, Stefania Ceruti, Paul Chazot, Nan Chiang, Bice Chini, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H. Clapp, Réjean Couture, Helen M. Cox, Zsolt Csaba, Claes Dahlgren, Gordon Dent, Steven D. Douglas, Pascal Dournaud, Satoru Eguchi, Emanuel Escher, Edward J. Filardo, Tung Fong, Marta Fumagalli, Raul R. Gainetdinov, Michael L. Garelja, Marc de Gasparo, Craig Gerard, Marvin Gershengorn, Fernand Gobeil, Theodore L. Goodfriend, Cyril Goudet, Lukas Grätz, Karen J. Gregory, Andrew L. Gundlach, Jörg Hamann, Julien Hanson, Richard L. Hauger, Debbie L. Hay, Akos Heinemann, Deron Herr, Morley D. Hollenberg, Nicholas D. Holliday, Mastgugu Horiuchi, Daniel Hoyer, László Hunyady, Ahsan Husain, Adriaan P. IJzerman, Tadashi Inagami, Kenneth A. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Takio Kitazawa, Pawel Kozielewicz, Hans‐Jürgen Kreienkamp, Jyrki P. Kukkonen, Tobias Langenhan, Dan Larhammar, Katie Leach, Davide Lecca, John D. Lee, Susan E. Leeman, Jérôme Leprince, Xaria X. Li, Stephen J. Lolait, Amelie Lupp, Robyn Macrae, Janet Maguire, Davide Malfacini, Jean Mazella, Craig A. McArdle, Shlomo Melmed, Martin C. Michel, Laurence J. Miller, Vincenzo Mitolo, Bernard Mouillac, Christa E. Müller, Philip M. Murphy, Jean‐Louis Nahon, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne‐Marie O’Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Roger G. Pertwee, Jean‐Philippe Pin, Eric R. Prossnitz, Mark Quinn, Rithwik Ramachandran, Manisha Ray, Rainer K. Reinscheid, Philippe Rondard, G. Enrico Rovati, Chiara Ruzza, Gareth J. Sanger, Torsten Schöneberg, Gunnar Schulte, Stefan Schulz, Deborah L. Segaloff, Charles N. Serhan, Khuraijam Dhanachandra Singh, Craig M. Smith, Leigh A. Stoddart, Yukihiko Sugimoto, Roger Summers, Valerie P. Tan, David Thal, Walter ( Wally) Thomas, Pieter B. M. W. M. Timmermans, Kalyan Tirupula, Lawrence Toll, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Jean‐Pierre Vilardaga, Christopher S. Walker, Ji Ming Wang, Donald T. Ward, Hans‐Jürgen Wester, Gary B. Willars, Tom Lloyd Williams, Trent M. Woodruff, Chengcan Yao, Richard D. Ye   +165 more
wiley   +1 more source

Ventricular tachycardia triggered by the first dose of an adenoviral vector‐based COVID‐19 vaccine in an adult patient with congenital heart disease

Clinical Case Reports, Volume 10, Issue 9, September 2022., 2022
Abstract A unique adverse event of adenoviral COVID‐19 vaccine in an adult patient with congenital heart disease is reported.
Pier Paolo Bassareo, Klevis Mihali, Kevin Patrick Walsh   +2 more
wiley   +1 more source

β‐Adrenergic signaling in skin cancer

FASEB BioAdvances, Volume 4, Issue 4, Page 225-234, April 2022., 2022
Abstract Activation of the sympathetic nervous system releases catecholamines that can interact with β‐adrenergic receptors on tumor cells. Preclinical models have shown that the signaling processes initiated by activation of β‐adrenergic receptors increase tumorigenesis, stimulate cell proliferation, and inhibit apoptosis.
Jennifer Batalla‐Covello, Shahrukh Ali, Tongxin Xie, Moran Amit   +3 more
wiley   +1 more source

Impact of Variability in Blood Pressure and Heart Rate on Beta-Blocker Adherence. [PDF]

J Clin Hypertens (Greenwich)
ABSTRACT Adherence to antihypertensive medications is essential for blood pressure (BP) control, influencing long‐term outcomes in hypertensive patients. This study examines the association between visit‐to‐visit variability in BP and heart rate (HR) and its effect on adherence to beta‐blocker therapy among outpatients.
Li Y, Sun JY, Guo QY, Han HY, Jia DA, Zhou ZM, Wang ZJ, Zhao YX, Zhou YJ, Yang SW.   +9 more
europepmc   +2 more sources