Results 41 to 50 of about 13,602,109 (265)

Perilipin‐2‐Anchored Lipid Droplet‐Targeting Phototheranostics

Angewandte Chemie, EarlyView.
This study reports two NIR theranostic dyes, C‐BDP‐OH and C‐BDP‐OMe. C‐BDP‐OMe targets lipid droplets via a dual‐anchoring mechanism with PLIN2, enabling wash‐free tumor imaging. With 62.6% photothermal conversion efficiency, it achieves tumor ablation by downregulating PLIN2, disrupting LD‐mitochondria crosstalk, and triggering apoptosis and ...
Lipeng Zhang, Jiyoung Yoo, Juan Bai, Sunghyun Kim, Yesim Bakan, Yongbin Zhang, Fangjun Huo, Jingying Zhou, Caixia Yin, Jong Seung Kim   +9 more
wiley   +2 more sources

Environment-Guided Localization via Factor Graph Inference Under Obstructed Line-of-Sight Conditions

IEEE Journal of Indoor and Seamless Positioning and Navigation
Indoor localization is a key technology for the safe operation of automatic guided vehicles (AGVs) in smart factories. The time-of-arrival (TOA) observations provide physically interpretable distance measurements, and TOA-based localization can be ...
Shino Shiraki, Takahiro Matsuda, Yoshiaki Nishikawa, Eiji Takahashi, Takeo Onishi, Toshiki Takeuchi, Kazushi Muraoka   +6 more
doaj   +1 more source

Design and Development of a Near Isotropic Printed Arc Antenna for Direction of Arrival (DoA) Applications

, 2021
This research presents an easy to fabricate isotropic printed arc antenna element to be used for direction of arrival (DoA) arrays. The proposed antenna exhibits a total gain variation of 0.5 dB over the entire sphere for 40 MHz impedance bandwidth at 1 ...
H. Ali, Saifullah Amin, M. Amin, Moazam Maqsood, A. R. Maud, M. Yusuf   +5 more
semanticscholar   +1 more source

Research on Systematic Design and Installation Based on Explosion Protection Technology Combined with Traction Elevator

MATEC Web of Conferences, 2018
According to GB, NEC, ASME17.1, ANSI A10.4 and EN 81.1 standard, there is a danger of explosive gas or dust. And then for elevator explosion protection, we design a device type up to requirements of NEC Class 1, Division 1, Group C&D as well as NEC Class
Li Changming, Wang Qibing, Leng Yonggang, Li Yu   +3 more
doaj   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

Advanced Science, EarlyView.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu, Qiu Peng, Xiaoyue Zhang, Zhengshuo Li, Yangge Wu, Yuqing Wen, Run Zheng, Shuanglong Wu, Chenfei Zhou, Zhengyu Hu, Lanjun Shu, Xinyi Ma, Qiuyang Li, Ya Ma, Chunlin Ou, Ming Zhao, Songqing Fan, Lingyu Wei, Jian Ma   +18 more
wiley   +1 more source

Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems

Advanced Science, EarlyView.
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen, Wenliang Zhou, Lan Qiu, Han Lai, Mingpan Huang, Qian Li, Wen Yu, Pei‐Yuan Qian, Fuwen Wei   +8 more
wiley   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

Advanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang, Ziyan Cao, Kexin Gao, Shuxin Yao, Yanbing Zheng, Manman Cui, Rong Yin, Guoqiang Han, Jin Hu, Chengyi Wang, Haojian Zhang   +10 more
wiley   +1 more source

Necrotising enterocolitis suspicion in newborns with duct-dependent congenital heart disease: prognosis and risk factor

BMJ Paediatrics Open
Introduction The main risk factors of necrotising enterocolitis (NEC) are prematurity and low birth weight. The aim of our study was to identify risk factors for NEC in patients with duct-dependent congenital heart disease (CHD).Study design Newborns ...
Isabelle Ligi, Caroline Ovaert, Fedoua El Louali, Camille Prom, Belghiti Alaoui Myriem, Celia Gran, Virginie Fouilloux, Marien Lenoir, Fabrice Michel   +8 more
doaj   +1 more source

TÜBİTAK 1MV Accelerator Mass Spectrometer Designed for 14C, 10Be, 26Al, 41Ca, 129I

Bulletin of the Mineral Research and Exploration, 2023
A 1 MV Accelerator Mass Spectrometer (AMS) was established at TÜBİTAK, MRC Türkiye in December 2015. The 1MV TÜBİTAK AMS system is based on a Pelletron tandem accelerator, operating up to 1.1MV.
Furkan Kulak, Erhan İlkmen, Turhan Doğan   +2 more
doaj   +1 more source