Results 51 to 60 of about 9,309,608 (281)

Design and Validation of Blast Non-propagation Wall for Multi-Compartmented Explosive Storage Structure of Capacity 5T NEC per Compartment

Defence Science Journal, 2018
Conventional magazines for hazard division 1.1 are constructed using bricks and reinforced cement concrete (RCC) for which storage inside quantity distance (SIQD) is 2.4 W1/3 m, where W is Net Explosive Content in kg. New composite called laced reinforced concrete (LRC) has been developed recently, for which SIQD has been reduced up to 0.5 W1/3 m.
Rajiv Narang, Ghanshyam Kumar Mishra, Rajesh Kumar Tanwar, Rajesh Mishra, Prabhanjan Kumar Thakur   +4 more
openaire   +2 more sources

Basic Variables of Design Education Approaches Comparison between the Design Education Systems in Egypt and in Germany

, 2021
There are many aspects and different variables shaping and affecting on any approach of design education. These differences depending on many related crossed issues such as; the cultural atmosphere (historical background, language, religion ...
Abdelrazik, Ahmed
core   +1 more source

DIXDC1 Promotes Lymphatic Metastasis and Resistance to Cuproptosis in Bladder Cancer Through Mediating DLAT

Advanced Science, EarlyView.
DIXDC1 drives bladder cancer progression by binding and stabilizing DLAT. This axis enhances NEK7 and CCNE2 mRNA stability to promote proliferation and lymphatic metastasis, while limiting copper‐induced DLAT oligomerization to reduce cuproptosis sensitivity, identifying DIXDC1 as a potential target linking metastasis with cuproptosis resistance ...
Hongqiong Li, Liang Cheng, Xiaole Lu, Haonan Dong, Shi Fu, Hongjin Shi, Mingsheng Liu, Chenwei Yang, Yuhang Huang, Zehua Chen, Yawei Zhang, Kaiwen Jie, Xiaoyue Zhang, Xiang Kui, Xinni Ye, Siting Chen, Xu Chen, Haifeng Wang   +17 more
wiley   +1 more source

Elevated DUOX2 levels correlate with necrotizing enterocolitis development

Frontiers in Cellular and Infection Microbiology
BackgroundNeonatal necrotizing enterocolitis (NEC) is a life-threatening intestinal disease primarily affecting preterm infants. Although the exact pathophysiology remains unclear, immune responses and redox reactions play crucial roles in its ...
Wenqiang Sun, Wenqiang Sun, Xue Liu, Xue Liu, Jiahui Huang, Jiahui Huang, Yihui Li, Yihui Li, Wei Zhai, Xinyun Jin, Xinyun Jin, Lili Li, Xueping Zhu, Xueping Zhu   +13 more
doaj   +1 more source

Discovery and Optimization of AMT‐676, a CDH17‐Targeting ADC for the Treatment of Advanced Gastrointestinal Cancers

Advanced Science, EarlyView.
AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang, Dan‐yun Ruan, Jing Shi, Yue Huang, Hui Sheng, Ya‐ling Huang, Linjie Ma, Lijun Wang, Caiwei Chen, Yixuan Wang, Yue Zhang, Yi Shen, Qing Zhang, Jianjian Zhang, Yanfang Tang, Jin‐ling Zhang, Jia‐jia Hu, Chen‐yi Wu, Jia‐ying Chen, Xun Meng, Shu‐Hui Liu, Feng Wang   +21 more
wiley   +1 more source

Metabolomic signatures distinguish the impact of formula carbohydrates on disease outcome in a preterm piglet model of NEC

Microbiome, 2018
Background Major risk factors for necrotizing enterocolitis (NEC) include premature birth and formula feeding in the context of microbial colonization of the gastrointestinal tract. We previously showed that feeding formula composed of lactose vs.
Lee Call, Barbara Stoll, Berthe Oosterloo, Nadim Ajami, Fariha Sheikh, Anja Wittke, Rosaline Waworuntu, Brian Berg, Joseph Petrosino, Oluyinka Olutoye, Douglas Burrin   +10 more
doaj   +1 more source

Open-Source Philosophy in Fashion Design: Contesting Authorship Conventions and Professionalism [PDF]

, 2020
This paper investigates open-source fashion approach as a design philosophy and a phenomenon that demonstrates an alternative to the concept of authorship of fashion designers.
Annamari Vänskä, Vänskä, Annamari, Särmäkari, Natalia, Natalia Särmäkari   +3 more
core   +1 more source

High Upper Critical Field and Type II Superconductivity in Epitaxial Cubic W2N Thin Films

Advanced Science, EarlyView.
Superconducting thin films of stoichiometric W2N demonstrate a high upper critical field (Hc2) of ∼ 8.5 T, uncommon among binary transition metal nitrides. This robust superconducting response under high magnetic fields highlights the technological relevance of W2N for superconducting applications, e.g., integrated quantum and cryogenic electronics ...
Aditya Singh, Arnaud le Febvrier, Sanath Kumar Honnali, Abhisek Mishra, Grzegorz Greczynski, Subhankar Bedanta, Per Eklund, Ajay Soni   +7 more
wiley   +1 more source

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

Advanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu, Ruotong Li, Xiaoyue Zhang, Dandan Chen, Jianmeng Yang, Mengmeng Li, Yuhan Yin, Ya Wang, Yuqiu Tian, Haoling Yan, Dan Cui, Jiangping Song, Gaoliang Ouyang   +12 more
wiley   +1 more source

An ant colony genetic fusion routing algorithm based on soft define network

IET Networks, EarlyView., 2022
Abstract Aiming at the problem that there are many paths in data forwarding in soft define network (SDN) network, and the optimal path is difficult to find, combined with the advantages of ant colony algorithm and Genetic algorithm (GA), a routing control strategy based on the ant colony genetic fusion algorithm is proposed.
Kaixin Zhao, Yong Wei, Yang Zhang
wiley   +1 more source