Results 51 to 60 of about 10,790,234 (269)

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source

EBV NEC buds synthetic membranes.

, 2022
(A) EBV NEC constructs used. Sequence of EBV BFLF2 1–67 are shown. (B) A diagram of the in-vitro budding assay. GUVs (red) bind NEC (purple and pink) which generates formation of membrane curvature allowing cascade blue (light blue) to enter the forming ...
Ekaterina E. Heldwein (12975804), Elizabeth B. Draganova (13021611), Michael K. Thorsen (13021608)   +2 more
core   +1 more source

Lithium‐related adverse drug reactions in children: A case–control study comparing lithium to second‐generation antipsychotics in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to improve the understanding of lithium's safety profile by analysing the frequency and distribution of reported adverse drug reactions (ADRs) compared to second‐generation antipsychotics (SGAs). Methods Individual case safety reports from VigiBase (1968–October 2023) involving individuals older than 2 years, with lithium or SGAs ...
Lisa T. Ringeling, Ravish N. Gangapersad, Lillian Lieuw, Patrick C. Souverein, Eibert R. Heerdink, Pilar Garcia‐Gomez, Manon H. J. Hillegers, Birgit C. P. Koch, Bram Dierckx   +8 more
wiley   +1 more source

Utility of GutCheck-NEC and e-NEC Scoring Systems in Assessing the Risk of Necrotizing Enterocolitis in Preterm Infants

Introduction: Necrotizing enterocolitis (NEC) is one of the leading gastrointestinal emergencies causing significant morbidity and mortality in premature neonates. This study aimed to evaluate the effectiveness of the GutCheck-NEC (GCN) and e-NEC scoring
Oruncu, Berna Egehan, Hırfanoğlu, İbrahim Murat, Berna Egehan Örüncü, Nuriye Ebru Ergenekon, Canan Türkyılmaz, Eray Esra Önal, Ergenekon, Nuriye Ebru, İbrahim Murat Hirfanoğlu, Koç, Esin, Esin Koç, Önal, Eray Esra, Türkyılmaz, Canan   +11 more
core   +1 more source

Quercetin‐zinc coordination polymer coated CaCO3 nanoparticles potentiate radiotherapy through reprogramming tumor immunosuppression

BMEMat, EarlyView.
Synthesis of QZCaCO3‐PEG to synergistically enhance the immunogenicity of radiotherapy through concurrent Zn2+‐induced cancer cell pyroptosis and Que‐mediated hypoxia amelioration through sequentially suppressing TGF‐β secretion and ECM deposition. Abstract Radiotherapy has demonstrated broad applications in treating solid tumors, but the hostile tumor
Chunjie Wang, Hengze Ding, Yu Hao, Honglin An, Ziliang Dong, Minming Chen, Yujie Zhu, Quguang Li, Bin Huang, Liangzhu Feng   +9 more
wiley   +1 more source

DNA methylation in necrotizing enterocolitis

Expert Reviews in Molecular Medicine
Epigenetic modifications, such as DNA methylation, are enzymatically regulated processes that directly impact gene expression patterns. In early life, they are central to developmental programming and have also been implicated in regulating inflammatory ...
Lauren C. Frazer, Yukihiro Yamaguchi, Dhirendra K. Singh, Natalia S. Akopyants, Misty Good   +4 more
doaj   +1 more source

Effect of ZnO Nanoparticles enhanced compost with different application methods on nutrient uptake and Grain Yield of Rice (Oryza sativa) Var. Inpari 32 [PDF]

BIO Web of Conferences
A pot experiment using a randomized block design was conducted to test the effect of ZnO-nanoparticles enhanced compost (ZnONEC) with different application methods on nutrient uptake and grain yield of rice var. Inpari 32.
Nurhidayati Nurhidayati, Basit Abdul, Tito Sama’ Iradat, Qur’ania Anita   +3 more
doaj   +1 more source

Intestinal morphology of NEC patients.

, 2013
Ileal tissues from NEC patients were stained with hematoxylin and eosin and representative sections are shown. (A) Ileum of an A-NEC-XBP1u patient with severe morphological damage. (B) Ileum of an A-NEC-XBP1u patient with mild morphological damage. (C)
Marie-Chantal Struijs (475804), Jiaping Mei (475805), Janneke Witte-Bouma (158108), Peng Lu (158125), Ingrid B. Renes (158153), Johannes B. van Goudoever (5652046), Adrianus C. J. M. de Bruijn (158117), Anita M. Korteland-van Male (158112)   +7 more
core   +1 more source

A bioinspired catalytic nanoplatform for ferroptosis‐immunotherapy synergy in metastatic cancer

BMEMat, EarlyView.
The bioinspired nanoplatform MnMSN@MnP‐PEG co‐delivers manganese peroxidase and manganese ions to synergistically induce immunogenic ferroptosis and activate the cGAS‐STING pathway, eliciting potent antitumor immunity against primary and metastatic tumors.
Panpan Xue, Hai Cai, Ying Sun, Yaxin Ma, Siyuan Liu, Jinying Zhu, Yan Chen, Xuemei Zeng, Shuangqian Yan   +8 more
wiley   +1 more source

Surgery for intestinal injuries in very preterm infants: a Norwegian population-based study with a new approach to disease classification

BMJ Paediatrics Open
Objective To evaluate population-based data on very preterm infants (<32 weeks gestation) operated for intestinal injuries, focusing on necrotising enterocolitis (NEC) and focal intestinal perforation (FIP).Design Nationwide, population-based registry
Claus Klingenberg, Ragnhild Støen, Kristin Bjørnland, Hans Jørgen Stensvold, Arild Rønnestad, Nina Clare Hapnes, Thorstein Sæter, Hans Jørgen Timm Guthe, Sissel Jennifer Moltu   +8 more
doaj   +1 more source