Results 131 to 140 of about 34,308 (261)

Emerging Roles of Regulated Cell Death-mediated Inflammation in Pathophysiology of Ocular Diseases. [PDF]

J Ophthalmic Vis Res
Sheibani N.
europepmc   +1 more source

Cuproptosis Inducers in Cancer Therapy: State of the Art and Challenges

The Chemical Record, EarlyView.
Cuproptosis is emerging as a distinct copper‐dependent cell death pathway, highlighting copper as a potential metabolic vulnerability in cancer. This review examines how coordination chemistry, redox regulation, and nanomaterial design shape Cu reactivity and therapeutic outcomes.
Chiara Ragusa, Valentina Oliveri
wiley   +1 more source

Targeting necroptosis: how does exercise protect against metabolic dysfunction-associated fatty liver disease? [PDF]

Front Physiol
Song W, Ke Z.
europepmc   +1 more source

Rotenone Induces Morphological Damage and Reduction in Catecholamine Levels in the Central Nervous System of the Ascidian Styela plicata

Environmental Toxicology, EarlyView.
ABSTRACT Ascidians are invertebrates that occupy a key phylogenetic position as a sister group of the vertebrates. The organization of their central nervous system (CNS), with cortex and medulla, indicates a plesiomorphic character of the gray and white matter of vertebrates, making this group of animals useful for studies of neurodegenerative events ...
Andressa de Abreu Mello, Carlos Augusto Borges de Andrade Gomes, Rafaela Rocha dos Santos, Cintia Monteiro de Barros, Silvana Allodi   +4 more
wiley   +1 more source

Regulatory complexity and therapeutic targeting of the necroptosis network. [PDF]

Front Immunol
Niu L, Liu F, Zhao Y, Li J, Wang H.
europepmc   +1 more source

A STING for necroptosis

Cell Death & Differentiation
Marlena Nastassja Schlecht, Karolin Flade, Wulf Tonnus   +2 more
openaire   +2 more sources

Deciphering diverse cell‐death patterns to predict the prognosis and potential therapy target of hepatocellular carcinoma patients

VIEW, EarlyView.
Abstract Ninety percent of all primary liver malignancies are hepatocellular carcinomas (HCC), making liver cancer the third most common cause of cancer‐associated mortality. Different patterns of programmed cell death (PCD) are crucial for the survival of tumors, and they might serve as a prognostic marker for HCC.
Lin Ding, Qian Li, Wenjing Yang, Te Liu, Tongtong Tian, Yu Liu, Chunyan Zhang, Baishen Pan, Beili Wang, Fan Wu, Wei Guo   +10 more
wiley   +1 more source

RIPK 1 in Alzheimer's Disease: Research Progress Integrating Pathogenesis on Necroptosis-Related Neuroinflammation, and Potential Therapeutic Strategies. [PDF]

Biomedicines
Toklucu ES, Shen S, Wang C, Zhang C.
europepmc   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

USP22 suppresses trophoblast cell necroptosis in preeclampsia by stabilizing KAT2A-mediated histone acetylation at the SFRP1 promoter. [PDF]

J Transl Med
He L, Zhan F, Zheng S, Lin N.
europepmc   +1 more source