Results 191 to 200 of about 52,832 (305)

Bilirubin directly activates RIPK3 to induce non-classical necroptosis. [PDF]

open access: yesCell Discov
Xue Q   +19 more
europepmc   +1 more source

Microarray Gene Expression Analysis of Lesional Skin in Canine Vesicular Cutaneous Lupus Erythematosus (VCLE)

open access: yesVeterinary Dermatology, EarlyView.
Background: Vesicular cutaneous lupus erythematosus (VCLE) is a rare autoimmune disease in dogs and is considered the canine counterpart of human subacute cutaneous lupus erythematosus (SCLE). However, the molecular mechanisms underlying VCLE remain incompletely defined.
Treasa Keating   +5 more
wiley   +1 more source

Interaction between smoking and ATG16L1T300A triggers Paneth cell defects in Crohn’s disease [PDF]

open access: yes, 2018
Ahmadian   +21 more
core   +2 more sources

Necroptosis in Nonalcoholic Steatohepatitis

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2015
Jérémie Gautheron, PhD   +2 more
openaire   +3 more sources

Role of RIPK1/RIPK3/MLKL signalling pathway in sepsis‐associated acute kidney injury

open access: yesExperimental Physiology, EarlyView.
Abstract Sepsis‐associated acute kidney injury (SA‐AKI) is a common clinical syndrome in critically ill patients, and its high mortality rate is closely related to complex pathological mechanisms. Existing studies have shown that the pathophysiological process of SA‐AKI involves complex multi‐mechanism interactions, including an uncontrolled systemic ...
Huijun Yin, Jingyi Wang, Huirong Han
wiley   +1 more source

The mitochondrial‐targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial‐apoptotic but not necroptotic signalling during ovarian cancer

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend An evaluation of the degree to which mitochondrial hydrogen peroxide emission (mH2O2)‐mediated apoptotic and necroptotic signalling contributes to skeletal muscle atrophy in an orthotopic epithelial ovarian cancer (EOC) model. To determine whether attenuating mH2O2 could prevent regulated cell death signalling and mitigate muscle
Shahrzad Khajehzadehshoushtar   +15 more
wiley   +1 more source

Crosstalk between endoplasmic reticulum stress and mitochondrial homeostasis: A new perspective on ophthalmic disease treatment

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
The graphical abstract follows a top‐to‐bottom flow: stressors → ER–mitochondria crosstalk → ophthalmic diseases. The central panel highlights three core mitochondria‐associated membrane function axes, color‐coded as follows: light yellow for Ca2+ homeostasis, light blue for mitochondrial dynamics, and light red for mitophagy.
Luyang Jiang   +5 more
wiley   +1 more source

Pesticides Drive Liver Diseases Through Non-Apoptotic Regulated Cell Death Pathways. [PDF]

open access: yesDiseases
Khairullina Z   +8 more
europepmc   +1 more source

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