Results 211 to 220 of about 34,308 (261)

PolyProline Predictor: A web server for empirical sequence‐based prediction of polyproline II helices

open access: yesProtein Science, Volume 35, Issue 7, July 2026.
Abstract Polyproline II (PPII) helices are extended left‐handed secondary structures increasingly recognized for their roles in molecular recognition, signaling and within intrinsically disordered regions of proteins. Despite their functional importance, predicting regions with propensity to form PPII helices from sequence alone remains challenging due
Rubén López‐Sánchez   +3 more
wiley   +1 more source

Stimuli‐Responsive Aggregation‐Induced Emission Materials for Tumor Theranostics: Design Strategies and Biomedical Applications

open access: yesSmall Science, Volume 6, Issue 7, July 2026.
pH, enzyme, hypoxia/redox, temperature, and external trigger‐responsive AIE materials for tumor imaging and therapy. Smart‐responsive aggregation‐induced emission (AIE) materials have emerged as promising bio‐nanomaterials for tumor diagnosis and therapy due to their enhanced fluorescence in aggregated states, overcoming the aggregation‐caused ...
Zhaohua Xu   +8 more
wiley   +1 more source

Structural, Compositional, and Dielectric State Profiling in Label‐Free Single‐Cell Monitoring

open access: yesSmall Methods, Volume 10, Issue 13, 8 July 2026.
Label‐free single‐cell monitoring leverages distinct physical interactions to access structural, compositional, and dielectric states of cells, enabling non‐perturbative, repeatable, and information‐rich measurements across diverse biological contexts. This review organizes representative platforms by intrinsic state variables and connects measurement ...
Changi Baek   +6 more
wiley   +1 more source

A Non‐Canonical Role for Hepatocyte MLKL in Promoting Mitochondrial Dysfunction and Senescence in the Aging Liver

open access: yesAging Cell, Volume 25, Issue 7, July 2026.
Aging‐associated MLKL upregulation in hepatocytes induces mitochondrial dysfunction and oxidative stress, accompanied by increased release of pro‐inflammatory extracellular vesicles. These changes are associated with increased p16+/p21+ senescence in hepatocytes and non‐parenchymal cells (macrophages, stellate cells, and endothelial cells), suggesting ...
Sabira Mohammed   +21 more
wiley   +1 more source

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