Results 241 to 250 of about 51,913 (289)

Regulated cell death in sepsis-associated liver injury: molecular mechanisms and therapeutic implications. [PDF]

Front Immunol
Zou K, Wang N, Wang L, Zhu Z, Gu M, Zhang J.   +5 more
europepmc   +1 more source

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

Advanced Science, Volume 13, Issue 14, 9 March 2026.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai, Yaqi Li, Shengnan Liu, Minjuan Wu, Zhixiao Liu, Junfeng Jiang, Jingjing Chen, Xiaoding Xu, Li Li, Chaoqun Li, Fang Zhao, Ye Liu, Haitao Ni, Tengfei Zhang, Mingjuan Xu, Chaofeng Han   +15 more
wiley   +1 more source

Treatment of Inflammatory Bowel Disease with Drugs Targeting PANoptosis: A Comprehensive Review. [PDF]

Biomedicines
Triantafillidis JK, Karakatsanis S.
europepmc   +1 more source

Quantification of Single‐Cell Cysteine Using an Electrochemical Nanosensor for Predicting Tumor Disulfidptosis Susceptibility

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Cysteine attracts interest due to its unique electrochemical activity and emerging relationship with disulfidptosis. This study develops a new electrochemical nanosensor, which represents the first of its kind capable of detecting intracellular cysteine for various types of tumor cells and primary tumor cells in mice to evaluate disulfidptosis ...
Congcong Zhang, Xiangdi Zhang, Shushen Li, Yuyang Li, Bei Yuan, Mingshuang Zheng, Shuo Zhang, Fangping Yuan, Min Jia, Lixia Lu, Jun Zhou, Zhenguo Zhang, Xin Du   +12 more
wiley   +1 more source

Expression of Concern: Shikonin Kills Glioma Cells through Necroptosis Mediated by RIP-1. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

BAK and BAX: Therapeutic Targets for Acute Myocardial Infarction and Myocardial Ischemia-Reperfusion Injury. [PDF]

Biology (Basel)
Xu Z, Meng F, Yang H, Liu Y, Ye K, Qin F, Liu D, Dai H.   +7 more
europepmc   +1 more source

Role of Disulfidptosis in the Local Inflammatory Response of Atopic Dermatitis

Clinical and Translational Allergy, Volume 16, Issue 3, March 2026.
ABSTRACT Background Understanding cell death pathways is critical for elucidating the mechanisms underlying inflammation in atopic dermatitis (AD). This study investigates the role of disulfidptosis, a novel form of programmed cell death, in AD pathogenesis.
Dong‐Mei Zhou, Cheng Chen, Yuan‐Fen Liao, Xi‐Meng Ma, Xin‐Hui Gong, Cheng‐Jun Cui, Yu‐Bao Cui   +6 more
wiley   +1 more source

Identification of PANoptosis hub genes driving immune activation and tubulointerstitial injury in diabetic kidney disease by integrative bioinformatics and machine learning. [PDF]

Front Immunol
Chen Y, Yuan F, Li S, Liu L, Peng X, Zeng X, Chen S, Liu N, Zhao T.   +8 more
europepmc   +1 more source

ALKBH3 suppresses ischemia/reperfusion‐induced PANoptosis by regulating the ZBED6/STAT1/AIM2 axis through m1A demethylation

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
ALKBH3 alleviates myocardial ischemia/reperfusion injury by suppressing PANoptosis. ALKBH3 promotes ZBED6 translation via mRNA m1A demethylation. ZBED6 promotes the interaction between STAT1 and NEDD4L to facilitate STAT1 ubiquitination and subsequent degradation.
Hongtao Diao, Chunlei Wang, Yuting Xiong, Qiaoyue Zhao, Xinyue Zhang, Xiaohui Qi, Yuan Zou, Jiaxuan Li, Linghua Zeng, Wei Si, Feng Zhang, Ping Pang, Ning Wang, Yu Bian, Baofeng Yang   +14 more
wiley   +1 more source

Dissecting Cell Death Pathways in Influenza A Virus Infection: Comparative Insights from Human Models. [PDF]

Viruses
Nguyen NMK, West AC, Ambrose RL, Tate MD.   +3 more
europepmc   +1 more source