A Cationic Block Co‐Polymer for Gene Delivery in the Posterior Segment of the Eye
ABSTRACT Diseases of the back of the eye such as neovascular age‐related macular degeneration (nAMD) are vision threatening and treatment is burdensome for patients, often requiring ocular injections every other month. Injection risks and logistics lower patient compliance; however, even patients receiving optimal treatment can deteriorate.
Amber Monteiro +8 more
wiley +1 more source
Unlocking the Secrets of Regulated Cell Death in Large B-Cell Lymphoma Beyond Apoptosis: Signaling Pathways and Therapeutic Options. [PDF]
Tkachenko A, Havranek O.
europepmc +1 more source
Punicalagin targets ovarian cancer via multiple anti‐cancer mechanisms. This graphical abstract summarizes the key findings of the study on the effects of Punicalagin (PCG), a pomegranate‐derived polyphenol, on ovarian cancer cells (OVCAR‐3 and SKOV‐3).
Zeeshan Ahmad Bhutta +4 more
wiley +1 more source
AHR-CYP1A1 Axis Perturbation and Necroptosis in 1,2-Dichloroethane Hepatotoxicity: Elucidation by an Integrated Network Toxicology and In Vitro Validation. [PDF]
Liu Y +6 more
europepmc +1 more source
Liver Stiffness Characterization of OGTLKO Mouse Model of Progressive Liver Fibrosis
Objectives O‐GlcNAcylation plays a key regulatory role in hepatic physiology, and its disruption leads to fibrosis in liver‐specific OGT knockout mice (OGTLKO), making this model valuable for studying advanced metabolic dysfunction‐associated steatohepatitis (MASH).
Gilles Renault +9 more
wiley +1 more source
The predictive value of necroptosis-related lncRNAs in prostate cancer prognosis and their potential to distinguish between cold and hot tumors. [PDF]
Zhang K +5 more
europepmc +1 more source
PANoptosis as a Potential Therapeutic Target in Drug-Induced Liver Injury: A Narrative Review. [PDF]
Zhang X +7 more
europepmc +1 more source
ABT-737 efficiently inhibits hepatocellular carcinoma cell activity via regulating PANoptosis. [PDF]
Deng B +5 more
europepmc +1 more source
Macrophage-derived galectin-3 contributes to pyroptosis, apoptosis and necroptosis through TLR4/MyD88/NF-κB/NLRP3 during atherosclerosis. [PDF]
Yuan Z +5 more
europepmc +1 more source

