Results 1 to 10 of about 165 (97)
Statin-Induced Autoimmune Necrotizing Myopathy [PDF]
Journal of Primary Care and Community Health, 2021 Statin therapy is a widely prescribed medication class for hypercholesterolemia. In statin-induced autoimmune myopathy, genetically predisposed and at-risk patients can develop antibodies against hydroxy-3-methylglutaryl-CoA reductase (HMGCR), the key ...
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Statin-Induced Necrotizing Autoimmune Myopathy
JACC: Case Reports, 2020 Statin-induced necrotizing autoimmune myopathy (SINAM) is an exceptionally rare yet devastating complication of statin therapy that can occur at any time after initiation.
Manasi Tannu, Laurence Sperling
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Statin‐associated necrotizing autoimmune myopathy with concurrent myasthenia gravis [PDF]
Clinical Case Reports (discontinued), 2021 Statin treatment has been associated with necrotizing autoimmune myopathy and has been linked to myasthenia gravis. We present an unprecedented clinical challenge with both disorders occurring in a patient treated with statins few months earlier.
Emma Frasson +2 more
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Necrotizing autoimmune myopathy
Annals of Indian Academy of Neurology, 2016 Necrotizing autoimmune myopathy (NAM) is categorized as one of the idiopathic immune-mediated myopathies. It is characterized by subacute predominantly proximal weakness, elevated serum creatine kinase, and a muscle biopsy showing predominantly necrotic and regenerating fibers with absent or minimal inflammation.
Sachin Suresh Babu +5 more
doaj +6 more sources
Necrotizing Autoimmune Myopathy: A Rare Variant of Idiopathic Inflammatory Myopathies [PDF]
Journal of Investigative Medicine High Impact Case Reports, 2017 Idiopathic inflammatory myopathies are an unusual group of myopathies with annual incidence of 1 in 100 000 people in the United States. Necrotizing autoimmune myopathy comprises only 16% of this group.
Noman Ahmed Jang Khan MD +4 more
doaj +3 more sources
Statin-induced necrotizing autoimmune myopathy: a systematic review
Rheumatology, 2022 Statins are a class of lipid-lowering medications used worldwide by millions of people and are safe for frequent use in most patients. However, they cause necrotizing autoimmune myopathy in some patients. We reviewed case reports of 80 patients from 2010
Manoj Reddy Somagutta +9 more
doaj +3 more sources
SAGE Open Medical Case Reports, 2023 Although 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase inhibitors are well tolerated, a small subset of patients may develop autoimmune myopathy, classified as immune-mediated necrotizing myopathy.
Marina Roytman, Hunza Chaudhry
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Seronegative necrotizing autoimmune myopathy with favorable response to intravenous immunoglobulin
Baylor University Medical Center Proceedings, 2021 We describe a 68-year-old man who presented with progressive weakness in proximal muscles of all four limbs and was found to have autoantibody-negative necrotizing autoimmune myopathy (NAM). His myopathy was refractory to corticosteroids and methotrexate, but subsequently demonstrated successful response to intravenous immunoglobulin (IVIG).
Rebecca Liu, Andrew Fenves
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An Unusual Case of Statin-Induced Myopathy: Anti-HMGCoA Necrotizing Autoimmune Myopathy [PDF]
Journal of General Internal Medicine, 2015 Statins are some of the most widely prescribed medications, and though generally well tolerated, can lead to a self-limited myopathy in a minority of patients. Recently, these medications have been associated with a necrotizing autoimmune myopathy (NAM).
Chamindra G Laverty +2 more
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Statin-induced necrotizing autoimmune myopathy: an extremely rare adverse effect from statin use
Journal of Community Hospital Internal Medicine Perspectives, 2019 Statins are widely prescribed medications to prevent cardiovascular events. While self-limited statin myopathy is relatively common, statin-induced necrotizing autoimmune myopathy (SINAM) is extremely uncommon, with incidence of two cases per million per
Rashmi Dhital +2 more
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