A Rapidly Progressive Case of Statin-induced Necrotizing Autoimmune Myopathy [PDF]
Cureus, 2020 Statins are one of the most commonly used medications to lower cholesterol and have been known to cause various side effects including myalgias, myopathies, and rhabdomyolysis. Statin-induced necrotizing autoimmune myopathy (SINAM), a subtype of inflammatory myopathy, is an exceedingly rare but severe side effect of statin use that manifests as ...
Ahmed, Sundus +3 more
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When Should a Patient with Statin-Induced Myopathy Be Re-challenged? A Case of Necrotizing Autoimmune Myopathy [PDF]
Case Reports in Rheumatology, 2018 Statins are notorious for causing myalgia and sometimes mild elevation of CPK (creatine phosphokinase). Herein, we present a case of necrotizing autoimmune myopathy induced by statins.
Elena Obreja +2 more
doaj +2 more sources
Treatment of Statin-Induced Necrotizing Autoimmune Myopathy With Glucocorticoid Monotherapy [PDF]
Cureus, 2020 Statins are widely prescribed medications to prevent cardiovascular events such as myocardial infarction and stroke. Both myalgia and myopathy are well-known potential side effects of statins. However, a rare and severe form of statin-induced necrotizing autoimmune myopathy (SINAM) has recently been described and can lead to debilitating weakness ...
Lempel, Matthew, Molla, Ermal
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Immunotherapy reversed myopathy but not cardiomyopathy in a necrotizing autoimmune myopathy patient with positive anti-SRP and MDA-5 autoantibodies [PDF]
BMC Cardiovascular Disorders, 2021 Background Necrotizing autoimmune myopathy (NAM) is pathologically characterized by myofiber necrosis and regeneration with paucity or absence of inflammatory cells in muscle biopsy.
Xue Ma, Li Xu, Yue Li, Bitao Bu
doaj +2 more sources
Necrotizing autoimmune myopathy: Clinicopathologic study from a single tertiary care centre [PDF]
Annals of Indian Academy of Neurology, 2018 Background: Idiopathic inflammatory myopathies (IIMs) are a group of chronic, autoimmune disorders which include a new entity, necrotizing autoimmune myopathy (NAM). NAM lacks inflammation and presents with markedly elevated creatinine phosphokinase (CPK)
Sobiya Mahnaz Ayesha +6 more
doaj +2 more sources
Statin-Induced Necrotizing Autoimmune Myopathy: Diagnosis and Treatment Approach [PDF]
JCEM Case ReportsAbstract The widespread use of statins for cardiovascular diseases has unveiled a new subset of inflammatory myopathy, immune-mediated necrotizing myopathy (IMNM). We describe below an unusual case of anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR) myopathy.
Varshini Srinivasan +3 more
openaire +3 more sources
A Case of Atorvastatin-Associated Necrotizing Autoimmune Myopathy, Mimicking Idiopathic Polymyositis [PDF]
Case Reports in Rheumatology, 2018 Statin-induced necrotizing autoimmune myopathy (SINAM) is a rare side effect of statin use which manifests as progressive muscle weakness. Because statins are a widely prescribed medication for coronary artery disease, hyperlipidemia, and many other ...
Ayushi Dixit, Adriana Abrudescu
doaj +2 more sources
Paraneoplastic Necrotizing Autoimmune Myopathy in a Patient Undergoing Laparoscopic Pancreatoduodenectomy for Distal Cholangiocarcinoma [PDF]
Case Reports in Gastroenterology, 2016 A 73-year-old male presented with jaundice and severe muscle weakness. He was diagnosed with distal cholangiocarcinoma and paraneoplastic necrotizing autoimmune myopathy (NAM).
Stefan van Dijk +5 more
doaj +2 more sources
Analysis on clinical features of necrotizing autoimmune myopathy
Chinese Journal of Contemporary Neurology and Neurosurgery, 2016 Objective To investigate the clinical manifestations and auxiliary examination features of necrotizing autoimmune myopathy (NAM). Methods According to the inclusion criteria from European Neuromuscular Center (ENMC) International Workshop on ...
Yi LI +7 more
doaj +1 more source
Statins and muscle – friends or foes? Discussions based on a case report [PDF]
Romanian Journal of Rheumatology, 2022 Immune-mediated necrotizing myopathy (IMNM) is a type of autoimmune myopathy characterized by relatively severe proximal weakness, myofiber necrosis with minimal inflammatory cell infiltrate on muscle biopsy, and infrequent extra-muscular involvement ...
Andra Patricia Stanciu +2 more
doaj +1 more source