Results 101 to 110 of about 39,677 (245)

Differential Effects of Human Immunodeficiency Virus Nef Variants on Pulmonary Vascular Endothelial Cell Dysfunction

Infectious Disease Reports
Background: Human Immunodeficiency Virus (HIV) infections remain a source of cardiopulmonary complications among people receiving antiretroviral therapy.
Amanda K. Garcia, Noelia C. Lujea, Javaria Baig, Eli Heath, Minh T. Nguyen, Mario Rodriguez, Preston Campbell, Isabel Castro Piedras, Edu Suarez Martinez, Sharilyn Almodovar   +9 more
doaj   +1 more source

nef-deleted HIV-1 inhibits phagocytosis by monocyte-derived macrophages in vitro but not by peripheral blood monocytes in vivo

, 2001
nef-deleted HIV-1 inhibits phagocytosis by monocyte-derived macrophages in vitro but not by peripheral blood monocytes in ...
H Chan (7732445), A Violo (13728565), J Hocking (13312737), J Mills (7665794), S Crowe (13428231), D Purcell (13728568), K Kedzierska (9863357), A Jaworowski (9684227), Johnson Mak (13082904), A Greenway (13711348), J Sullivan (9852734)   +10 more
core  

Molecular Chaperone Networks in Plants: Maintaining Proteostasis and Enhancing Stress Resilience for Crop Improvement

Plant, Cell &Environment, EarlyView.
ABSTRACT Molecular chaperones play a central role in the plant proteostasis machinery by aiding the folding of nascent proteins, preventing aggregation, and repairing or degrading damaged proteins. These functions are especially essential during abiotic and biotic stress, which can destabilise cellular proteins and disrupt metabolic homoeostasis.
Mingfang Yang, Anqin Gao, Tsz‐Yan Chan, Hafiz Mamoon Rehman, Sehar Nawaz, Sehrish Bashir, Noman Mahmood, Muhammad Wajid Ullah, Chunlin Long, Hon‐Ming Lam, Muhammad Arif   +10 more
wiley   +1 more source

ARF1 Regulates Nef-Induced CD4 Degradation [PDF]

, 2004
Background: The HIV Nef protein downregulates CD4 through sequential connection with clathrin-coated pits and the COP1 coatomer, resulting in accelerated endocytosis and lysosomal targeting.Results: Here we report that the small GTPase ARF1 controls the ...
Borel, Christelle, Sobo, Komla, Trono, Didier, Piguet, Vincent, Demaurex, Nicolas, Stalder Monney, Romaine, Stalder, Romaine, Gruenberg, Jean, Fauré, Julien   +8 more
core   +1 more source

Nonpathogenic SIV Infection in Sooty Mangabeys Is Characterized by a Lack of Activation and Expansion of Monocytes

Journal of Medical Primatology, Volume 55, Issue 5, October 2026.
ABSTRACT Introduction Natural hosts of simian immunodeficiency virus (SIV), including sooty mangabeys (SMs), maintain high viremia without progressing to AIDS and AIDS‐associated histopathogenesis. The mechanisms underlying this protection and lack of pathogenesis remain incompletely understood, particularly in relation to monocyte/macrophage ...
Caroline Soulas, Hai Duc Nguyen, Summer Siddiqui, Natalie Stahr, Tricia H. Burdo, Francis J. Novembre, Woong‐Ki Kim, Kenneth C. Williams   +7 more
wiley   +1 more source

Logique et ontologie des objets sociaux [PDF]

, 2015
Frédéric Nef, directeur d’études Compte rendu non ...
Nef, Frederic
core   +4 more sources

Nef-mediated enhancement of cellular activation and human immunodeficiency virus type 1 replication in primary T cells is dependent on association with p21-activated kinase 2

Retrovirology, 2011
Background The HIV-1 accessory protein Nef is an important determinant of lentiviral pathogenicity that contributes to disease progression by enhancing viral replication and other poorly understood mechanisms.
Olivieri Kevin C, Mukerji Joya, Gabuzda Dana   +2 more
doaj   +1 more source

Properties of a chimeric simian-human immunodeficiency virus expressing an hybrid HIV-1 Nef/SIVmac Nef protein

, 2002
International audienceThe nef genes of human and simian immunodeficiency viruses code for a membrane associated protein critical for AIDS development. SIVmac Nef presents C-terminal a 27 amino acid extension absent of HIV-1 Nef. To estimate the influence
Beyer, C., Gut, J., Cluet, D., Cecile, A., Bertsch, C., Gloeckler, L., Aubertin, A.   +6 more
core   +1 more source

Présentation

, 1983
Nef Frédéric. Présentation. In: Histoire Épistémologie Langage, tome 5, fascicule 2, 1983. La sémantique logique : Problèmes d'histoire et de méthode, sous la direction de Frédéric Nef.
Nef, Frédéric
core   +1 more source

HIV-1 Nef protein and the Nef-associating kinase PAK2 in cell signaling [PDF]

, 2010
HIV- eli immuunikatovirustartuntaa kantaa maailmassa arviolta yli 30 miljoonaa ihmistä. Suomessa ilmoituksia HIV-positiivisista henkilöistä oli vuoden 2010 alkuun mennessä kirjattu runsas kolme tuhatta, ja määrä on viime vuosina lisääntynyt noin ...
Pulkkinen, Kati
core