Results 11 to 20 of about 109,824 (227)

Ubiquitin E3 Ligase c-Cbl Is a Host Negative Regulator of Nef Protein of HIV-1

open access: yesFrontiers in Microbiology, 2020
Nef is an accessory protein encoded by human immunodeficiency virus type-1 (HIV-1) and plays important roles in regulating HIV-1 infection and viral replication.
Hong-Guang Zhang   +29 more
doaj   +1 more source

Strictly nef divisors [PDF]

open access: yesMathematische Annalen, 2008
Let $X$ be a projective manifold of dimension $n$ and $L$ a strictly nef line bundle on $X$. Then $K_X+tL$ is ample if $t > n+1$ in the following cases. 1.) $\text{dim} X = 3$ unless (possibly) $X$ is a Calabi-Yau with $c_2 \cdot L=0$; 2.) $ (X) \ge n-2$; 3.) $\text{dim} (X) \ge n-2$, with $ : X \to A$ the Albanese map.
Campana, F., Chen, J.A., Peternell, T.
openaire   +4 more sources

Modelling and in vitro testing of the HIV-1 Nef fitness landscape. [PDF]

open access: yes, 2019
An effective vaccine is urgently required to curb the HIV-1 epidemic. We have previously described an approach to model the fitness landscape of several HIV-1 proteins, and have validated the results against experimental and clinical data.
Barton, John P   +9 more
core   +2 more sources

Folie et société(s) au tournant du Moyen Âge et de la Renaissance

open access: yesBabel: Littératures Plurielles, 2012
Dans le chapitre d’ouverture de son Histoire de la folie, Foucault convoque pêle-mêle différents objets pour faire naître deux idées fortes : l’emblème que constitue la Nef des fous d’une part, et d’autre part le grand partage entre expériences cosmique ...
Christine Bénévent
doaj   +1 more source

Expression, intracellular targeting and purification of HIV Nef variants in tobacco cells [PDF]

open access: yes, 2007
Background Plants may represent excellent alternatives to classical heterologous protein expression systems, especially for the production of biopharmaceuticals and vaccine components.
Baschieri , Selene   +7 more
core   +3 more sources

Lower and upper bounds for nef cones [PDF]

open access: yes, 2011
The nef cone of a projective variety Y is an important and often elusive invariant. In this paper we construct two polyhedral lower bounds and one polyhedral upper bound for the nef cone of Y using an embedding of Y into a toric variety. The lower bounds
Gibney, Angela, Maclagan, Diane
core   +1 more source

The role of Nef in the long-term persistence of the replication-competent HIV reservoir in South African women. [PDF]

open access: diamondJ Virol
Ismail SD   +13 more
europepmc   +2 more sources

On a generalized canonical bundle formula for generically finite morphisms [PDF]

open access: yes, 2020
We prove a canonical bundle formula for generically finite morphisms in the setting of generalized pairs (with $\mathbb{R}$-coefficients). This complements Filipazzi's canonical bundle formula for morphisms with connected fibres.
Han, Jingjun, Liu, Wenfei
core   +3 more sources

COVID-19: What Iodine Maps From Perfusion CT can reveal—A Prospective Cohort Study

open access: yesCritical Care, 2020
Background Subtraction CT angiography (sCTA) is a technique used to evaluate pulmonary perfusion based on iodine distribution maps. The aim of this study is to assess lung perfusion changes with sCTA seen in patients with COVID-19 pneumonia and correlate
Mario G. Santamarina   +6 more
doaj   +1 more source

Smooth and Rough Positive Currents [PDF]

open access: yes, 2018
We study the different notions of semipositivity for (1,1) cohomology classes on K3 surfaces. We first show that every big and nef class (and every nef and rational class) is semiample, and in particular it contains a smooth semipositive representative ...
Filip, Simion, Tosatti, Valentino
core   +3 more sources

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