Results 71 to 80 of about 39,677 (245)

Globalizing Comparative Public Administration With Integrative Contextualization: State Autonomy in the Developmental Path of Hong Kong and Singapore

open access: yesPublic Administration and Development, EarlyView.
ABSTRACT The lack of a common variable for comparison has been a major obstacle to the development of Comparative Public Administration (CPA). State autonomy enables an integrative contextualization approach, allowing both the analysis of contextual individual country experiences and the generation of generalized comparable knowledge.
Wilson Wong
wiley   +1 more source

Oxaziridines: Versatile Reagents in Modern Organic Synthesis

open access: yesThe Chemical Record, EarlyView.
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra   +2 more
wiley   +1 more source

varioustoxins/NEF-Pipelines: 0.1.65

open access: yes
<h1>NEF-Pipelines</h1> <p>A set of command line (currently... there maybe a gui later!) tools for maniulating [NEF] or NMR Exchange Format files which can be used to move NMR meta data [peaks, shifts, sequences etc] between NMR data ...
varioustoxins, locsmith, gweatherby
core   +1 more source

HIV Pathogenesis: Nef Loses Control [PDF]

open access: yes, 2006
In this issue of Cell, Schindler et al. (2006) show that the Nef protein from nonpathogenic strains of simian immunodeficiency virus (SIV) induces the downregulation of host T cell receptor/CD3, whereas Nef from human immunodeficiency virus (HIV-1) does ...
Foster, John L., Garcia, J. Victor
core   +1 more source

Functional variation in butterfly egg pore traits: The potential role of climate

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Immobile eggs of terrestrial animals are exposed to variable environmental conditions. Insect egg pores, critical for gas exchange (aeropyles) and fertilisation (micropyles), are ecologically important yet understudied.
Teun de Jong   +4 more
wiley   +1 more source

Zeolin–Nef accumulates to much higher amounts than zein–Nef or Nef-zein

open access: yes, 2011
(A) Proteins were extracted with reducing buffer from young leaves of independent transgenic lines of tobacco expressing zeolin–Nef (lines L, N, and F), zein–Nef (16, 17, and 13), or Nef-zein (1 and 11) or from wild-type tobacco (wt). Analysis was by SDS–
Marika Rossi (52304)   +7 more
core   +1 more source

Beyond Westminster: How the Four‐Day Working Week Reached the UK Public Sector

open access: yesThe Political Quarterly, EarlyView.
Abstract The United Kingdom's emergence as a public sector pioneer in the four‐day working week debate presents a striking paradox. A post‐Thatcher liberal market economy hostile to statutory working‐time reform might be expected to resist government‐sponsored working‐time reduction in the public sector.
Joan Sanchis, Raúl de Arriba
wiley   +1 more source

Tetherin/BST-2 antagonism by Nef depends on a direct physical interaction between Nef and tetherin, and on clathrin-mediated endocytosis.

open access: yesPLoS Pathogens, 2013
Nef is the viral gene product employed by the majority of primate lentiviruses to overcome restriction by tetherin (BST-2 or CD317), an interferon-inducible transmembrane protein that inhibits the detachment of enveloped viruses from infected cells ...
Ruth Serra-Moreno   +3 more
doaj   +1 more source

Inhibition of the Nef regulatory protein of HIV-1 by a single-domain antibody

open access: yes, 2011
The Nef protein of HIV-1 is important for AIDS pathogenesis, but it is not targeted by current antiviral strategies. Here, we describe a single-domain antibody (sdAb) that binds to HIV-1 Nef with a high affinity (K(d) = 2 × 10(-9)M) and inhibited ...
Jolicoeur, Paul   +19 more
core   +1 more source

A validated 3D point‐cloud analysis workflow for the creation of seagrass canopy height models

open access: yesMethods in Ecology and Evolution, EarlyView.
Abstract Seagrasses support highly productive ecosystems in both temperate and tropical waters and provide essential ecosystem services. Despite their importance, the vertical structure of seagrasses (i.e. the canopy) remains poorly characterised at the microscale, even though it is a strong predictor of ecological processes that influence both ...
Daniele Ventura
wiley   +1 more source

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