Results 121 to 130 of about 12,704,228 (148)

Prognostic significance of immunologic changes in 675 infants perinatally exposed to human immunodeficiency virus

open access: yes, 1991
in c.o.l.l. con Italian Register for Human Immunodeficiency Virus Infection in Children   +1 more
core  

Purification and characterization of human immunodeficiency virus type 1 nef gene product expressed by a recombinant baculovirus

Virology, 1991
We have constructed the recombinant baculovirus which expresses the human immunodeficiency virus type 1 negative factor (nef) gene. Spodoptera frugiperda cells infected with the recombinant virus produced a 27-kDa protein which reacted with rabbit antisera raised against a carboxy-terminal synthetic peptide of the Nef protein by immunoblot analysis ...
Y, Matsuura   +7 more
openaire   +4 more sources

The Human Immunodeficiency Virus Type 1nefGene Can to a Large Extent Replace Simian Immunodeficiency VirusnefIn Vivo

open access: yesJournal of Virology, 1999
The nef gene of the pathogenic simian immunodeficiency virus (SIV) 239 clone was replaced with primary human immunodeficiency virus type 1 (HIV-1) nef alleles to investigate whether HIV-1 Nef can ...
Jacek SkowroĊ„ski   +2 more
exaly   +2 more sources

The nef gene products of both simian and human immunodeficiency viruses enhance virus infectivity and are functionally interchangeable

Journal of Virology, 1997
Adult rhesus macaques infected with nef-defective simian immunodeficiency virus (SIV) exhibit extremely low levels of steady-state virus replication, do not succumb to immunodeficiency disease, and are protected from experimental challenge with pathogenic isolates of SIV.
E, Sinclair, P, Barbosa, M B, Feinberg
openaire   +2 more sources

Human immunodeficiency virus-1 Nef protein interacts with Tat and enhances HIV-1 gene expression [PDF]

open access: yesFEBS Letters, 2003
The human immunodeficiency virus (HIV-1) Nef protein is now regarded as a regulatory protein responsible not only for establishment of infection and increased pathogenesis but also for enhancement of viral replication.
Debashis Mitra
exaly   +2 more sources

Immunogenicity of the Human Immunodeficiency Virus (HIV) Recombinant nef Gene Product. Mapping of T-Cell and B-Cell Epitopes in Immunized Chimpanzees

AIDS Research and Human Retroviruses, 1990
The nonstructural nef gene product of human immunodeficiency virus (HIV), p27, is a regulatory "early phase" protein produced by HIV-infected cells. As a possible negative regulator of transcription, it has been suggested that p27 may be involved in the control of HIV proviral latency. Immune
E, Bahraoui   +7 more
openaire   +2 more sources

Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp160 or viral entry

Journal of Virology, 1995
The nef gene product of human immunodeficiency virus type 1 (HIV-1) promotes more-rapid kinetics of viral replication in primary peripheral blood mononuclear cells. We have previously shown that these enhancing effects of Nef on HIV-1 replication reflect an increase in viral infectivity detectable both in limiting dilution assays and through a single ...
M D, Miller   +4 more
openaire   +2 more sources

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