Results 81 to 90 of about 7,192 (107)

Reporter-expressing viruses for antiviral drug discovery research. [PDF]

open access: yesFront Cell Infect Microbiol
Praditya DF, Waluyo D, Nozaki T.
europepmc   +1 more source

Replication-competent SIVcpz CRISPR screen identifies barriers to successful cross-species transmission

open access: yes
Xie Q   +12 more
europepmc   +1 more source

The nef gene products of both simian and human immunodeficiency viruses enhance virus infectivity and are functionally interchangeable

Journal of Virology, 1997
Adult rhesus macaques infected with nef-defective simian immunodeficiency virus (SIV) exhibit extremely low levels of steady-state virus replication, do not succumb to immunodeficiency disease, and are protected from experimental challenge with pathogenic isolates of SIV.
E, Sinclair, P, Barbosa, M B, Feinberg
openaire   +2 more sources

Purification and characterization of human immunodeficiency virus type 1 nef gene product expressed by a recombinant baculovirus

Virology, 1991
We have constructed the recombinant baculovirus which expresses the human immunodeficiency virus type 1 negative factor (nef) gene. Spodoptera frugiperda cells infected with the recombinant virus produced a 27-kDa protein which reacted with rabbit antisera raised against a carboxy-terminal synthetic peptide of the Nef protein by immunoblot analysis ...
Y, Matsuura   +7 more
openaire   +2 more sources

Immunogenicity of the Human Immunodeficiency Virus (HIV) Recombinant nef Gene Product. Mapping of T-Cell and B-Cell Epitopes in Immunized Chimpanzees

AIDS Research and Human Retroviruses, 1990
The nonstructural nef gene product of human immunodeficiency virus (HIV), p27, is a regulatory "early phase" protein produced by HIV-infected cells. As a possible negative regulator of transcription, it has been suggested that p27 may be involved in the control of HIV proviral latency. Immune
E, Bahraoui   +7 more
openaire   +2 more sources

Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp160 or viral entry

Journal of Virology, 1995
The nef gene product of human immunodeficiency virus type 1 (HIV-1) promotes more-rapid kinetics of viral replication in primary peripheral blood mononuclear cells. We have previously shown that these enhancing effects of Nef on HIV-1 replication reflect an increase in viral infectivity detectable both in limiting dilution assays and through a single ...
M D, Miller   +4 more
openaire   +2 more sources

[Function of human immunodeficiency virus type 1 nef gene product in virus replication].

[Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1996
We comparatively analyzed the replication kinetics of wild-type (wt) and nef mutant human immunodeficiency virus type 1 (HIV-1) in several CD4-positive cell lines, in order to clarify the molecular function of Nef protein. The delayed growth of nef mutant virus was observed at the initial stage of replication in all cell lines examined. This phenomenon
openaire   +1 more source

Cervical cancer prevention and control in women living with human immunodeficiency virus

Ca-A Cancer Journal for Clinicians, 2021
Philip E Castle, Vikrant V Sahasrabuddhe
exaly  

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