Results 121 to 130 of about 318,238 (318)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Distinguishing Entailment and Presupposition Under Negation Test

open access: yesLLT Journal: A Journal on Language and Language Teaching, 2016
Distinguishing entailment from presupposition is quite difficult because their semanticrelation seems to be similar. Both entailment and presupposition have an automaticrelationship based on the context.
Gatri Asti Putri Indarti
doaj   +1 more source

Extension of Yager's negation of a probability distribution based on Tsallis entropy

open access: yesInternational Journal of Intelligent Systems, 2019
The negation of probability distribution becomes an important topic since some problems are burdensome to deal with directly. Inspired by Yager's negation of probability distribution, an extension model to measure the negation of a probability ...
J. Zhang   +3 more
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Analyzing Iraqi University EFL Learners’ Recognition of Implicit ‎Negation in ‎English Language

open access: yesمجلة جامعة الأنبار للعلوم الإنسانية
Negation has been a challenging and difficult subject for philosophers, logicians and linguists alike. As a form of negation, implicit (implied, hidden, indirect) negation is a common type that would occur when lexical items, including different parts of
Hafedh Ibraheem Shabeeb
doaj   +1 more source

Solar cell and circuit array and process for nullifying magnetic fields Patent [PDF]

open access: yes, 1968
Negation of magnetic fields produced by thin waferlike circuit elements in space ...
Slifer, L. W., Jr.
core   +1 more source

The generalization negation of probability distribution and its application in target recognition based on sensor fusion

open access: yesInt. J. Distributed Sens. Networks, 2019
Target recognition in uncertain environments is a hot issue. Fusion rules are used to combine the sensor reports from different sources. In this situation, obtaining more information to make correct decision is an essential issue.
Xiaozhuan Gao, Yong Deng
semanticscholar   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

A controlled trial of automated classification of negation from clinical notes

open access: yesBMC Medical Informatics and Decision Making, 2005
Background Identification of negation in electronic health records is essential if we are to understand the computable meaning of the records: Our objective is to compare the accuracy of an automated mechanism for assignment of Negation to clinical ...
Carruth William   +6 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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