Results 51 to 60 of about 56,009 (267)
Ukraine and Canada: The European Union as a Partner in Negotiation
Історико-політичні проблеми сучасного світу, 2020 The European Union as a mode of European Unification is a good example of an international actor channelling negotiation processes in an optimal way. As both Ukraine and Canada will continue and probably intensify negotiation processes with the European
Пол В. Міртс
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The potential of generative AI for personalized persuasion at scale
Scientific ReportsMatching the language or content of a message to the psychological profile of its recipient (known as “personalized persuasion”) is widely considered to be one of the most effective messaging strategies.
S. C. Matz +5 more
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
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Proceedings of the first international joint conference on Autonomous agents and multiagent systems part 3 - AAMAS '02, 2002 Structured negotiation is proposed as a new method through which collaborating agents can seek consensus on the apportionment of tasks and resources. The approach draws on research in collaborative planning and human dialog understanding: agent interactions are organized in a manner that reflects the structure of a shared plan.
Charles L. Ortiz Jr., Eric Hsu
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Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
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FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Accounting for reciprocity in negotiation and social exchange [PDF]
Judgment and Decision Making, 2015 People generally adhere to the norm of reciprocity during both tacit and negotiated exchange. Emotional responses generated from profitable and unprofitable exchange facilitate the formation of motives to settle scores with others.
Alexandra A. Mislin +3 more
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