Results 31 to 40 of about 163,492 (267)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Argumentation-based negotiation [PDF]

, 2003
Negotiation is essential in settings where autonomous agents have conflicting interests and a desire to cooperate. For this reason, mechanisms in which agents exchange potential agreements according to various rules of interaction have become very ...
McBurney, P, Rahwan, I. ; https://orcid.org/, Sonenberg, L, Simon Parsons, Ramchurn, Sarvapali, McBurney, P., Peter Mcburney, Parsons, S., Sonenberg, L., Liz Sonenberg, Jennings, N. R., Ramchurn, S., Rahwan, I, Iyad Rahwan, Nicholas R. Jennings, Rahwan, I., Jennings, NR, Sarvapali D. Ramchurn, Parsons, S, Jennings, N.   +19 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Optimal negotiation strategies for agents with incomplete information

, 2001
This paper analyzes the process of automated negotiation between two competitive agents that have firm deadlines and incomplete information about their opponent.
Jennings, N. R., S. Shaheen Fatima, Fatima, S. S., Nicholas R. Jennings, Michael Wooldridge, Jennings, NR, Wooldridge, M, Wooldridge, M., Fatima, SS   +8 more
core   +1 more source

Exploring motivated reasoning in polarization over the unfolding 2023 judicial reform in Israel

Communications Psychology
This work explored polarization over Israel’s Judicial Reform, introduced in January 2023. We find that the reform divided people into pro- and anti-reform camps, which differed in characteristics such as institutional trust, patriotism, and national ...
Dora Simunovic, Anna Dorfman, Maayan Katzir   +2 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Grid Commerce, Market-Driven G-Negotiation, and Grid Resource Management [PDF]

, 2006
Although the management of resources is essential for realizing a computational grid, providing an efficient resource allocation mechanism is a complex undertaking.
Sim, Kwang Mong
core   +1 more source

EFFECTS OF NEGOTIATION PRACTICES ON PUBLIC PROCUREMENT PERFORMANCE IN TANZANIA: A CASE OF NATIONAL HEALTH INSURANCE FUND (NHIF)-HEAD OFFICE, DODOMA REGION

Хабаршысы. Экономика сериясы
This study evaluated the effect of effective negotiation practices on performance of public sector procurement. This study was carried out at the National Health Insurance Fund (NHIF).
Хамиси К. Сама, Фидель А. Чарукула   +1 more
doaj   +1 more source

THE SALARY NEGOTIATION STRATEGY [PDF]

Annals of the University of Petrosani: Economics, 2017
The negotiation is an inherent process in any human activity primarily aimed at reaching a consensus between two or more participating parties. One of the main concerns of the employees of any company is motivation through the salary level.
ANCA JARMILA GUŢĂ
doaj  

Caring for a child with a learning disability born into the family unit: women's recollections over time

Scandinavian Journal of Disability Research, 2011
Caring over time for a child/young adult with a learning disability requires that the family, and in particular the mother, negotiate their needs with services and professionals, and these negotiations are complicated further by significant behavioural ...
Andrew Lovell, Tom Mason
doaj   +1 more source