Results 21 to 30 of about 59,601 (220)

Evaluation of a Hydrogel-Based Diagnostic Approach for the Point-of-Care Based Detection of Neisseria gonorrhoeae

Antibiotics, 2018
Eleven primer pairs were developed for the identification of Neisseria gonorrhoeae. The sensitivity and specificity of these primers were evaluated by Real Time (RT)-PCR melt curve analyses with DNA from 145 N. gonorrhoeae isolates and 40 other Neisseria
Sumudu R Perera, Ali Taheri, Nurul H Khan, Rajinder P Parti, Stephanie Stefura, Pauline Skiba, Jason P Acker, Irene Martin, Anthony Kusalik, Jo-Anne R Dillon   +9 more
doaj   +1 more source

A paperfluidic platform to detect Neisseria gonorrhoeae in clinical samples [PDF]

, 2018
Globally, the microbe Neisseria gonorrhoeae (NG) causes 106 million newly documented sexually transmitted infections each year. Once appropriately diagnosed, NG infections can be readily treated with antibiotics, but high-risk patients often do not ...
Cabodi, Mario, Gaydos, Charlotte A., Hardick, Justin, Horst, Audrey L., Klapperich, Catherine M., Kolluri, Nikunja, Linnes, Jacqueline C., Rosenbohm, Justin M.   +7 more
core   +1 more source

Loop-Mediated Isothermal Amplification Assay for Identifying Neisseria gonorrhoeae Nonmosaic penA-Targeting Strains Potentially Eradicable by Cefixime

Microbiology Spectrum, 2022
Treatment regimens for gonorrhea have limited efficacy worldwide due to the rapid spread of antimicrobial resistance. Cefixime (CFM) is currently not recommended as a first-line treatment for gonorrhea due to the increasing number of resistant strains ...
Ken Shimuta, Hideyuki Takahashi, Yukihiro Akeda, Shu-ichi Nakayama, Makoto Ohnishi   +4 more
doaj   +1 more source

Opa-interacting protein 5 modulates docetaxel-induced cell death via regulation of mitophagy in gastric cancer

Tumor Biology, 2017
Damage to mitochondria induces mitophagy, a cellular process that is gaining interest for its therapeutic relevance to a variety of human diseases. However, the mechanism underlying mitochondrial depolarization and clearance in mitophagy remains poorly ...
Tae Woo Kim, Seon-Jin Lee, Young-Jun Park, Sang Yoon Park, Byung Moo Oh, Yun Sun Park, Bo-Yeon Kim, Young-Ha Lee, Hee Jun Cho, Suk Ran Yoon, Yong-Kyung Choe, Hee Gu Lee   +11 more
doaj   +1 more source

RESISTÊNCIA AOS ANTIBIÓTICOS EM NEISSERIA GONORRHOEAE – PASSADO, PRESENTE E FUTURO

Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2013
Introdução: A resistência aos antibióticos em Neisseria gonorrhoeae tem-se revelado um importante problema de saúde pública mundial, estando a levantar grandes dificuldades em termos de opções terapêuticas em alguns países.
Ermelindo Tavares, Cândida Fernandes, Maria José Borrego, Ana Rodrigues, Jorge Cardoso   +4 more
doaj   +1 more source

Rifampicin Resistance Associated with rpoB Mutations in Neisseria gonorrhoeae Clinical Strains Isolated in Austria, 2016 to 2020

Microbiology Spectrum, 2022
Due to increasing rates of antimicrobial resistance (AMR) in Neisseria gonorrhoeae, alternative treatments should be considered. To assess rifampicin’s potential as a gonorrhea treatment, we used rpoB mutations to estimate rifampicin resistance in ...
Justine Schaeffer, Kathrin Lippert, Sonja Pleininger, Anna Stöger, Petra Hasenberger, Silke Stadlbauer, Florian Heger, Angelika Eigentler, Alexandra Geusau, Alexander Indra, Franz Allerberger, Werner Ruppitsch   +11 more
doaj   +1 more source

Optimising the management of vaginal discharge syndrome in Bulgaria: cost effectiveness of four clinical algorithms with risk assessment [PDF]

, 2010
OBJECTIVES: To evaluate the performance and cost effectiveness of the WHO recommendations of incorporating risk-assessment scores and population prevalence of Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) into vaginal discharge syndrome (VDS)
Anguenot, J-L, Cavailler, P, Cornier, N, Dentcheva, R, Gerbase, A, Janin, A, Mayaud, P, Ninet, B, Petrova, E, Terris-Prestholt, F, Vassilakos, P   +10 more
core   +4 more sources

Synthetic DNA Delivery of an Optimized and Engineered Monoclonal Antibody Provides Rapid and Prolonged Protection against Experimental Gonococcal Infection

mBio, 2021
Neisseria ...
Elizabeth M. Parzych, Sunita Gulati, Bo Zheng, Mamadou A. Bah, Sarah T. C. Elliott, Jacqueline D. Chu, Nancy Nowak, George W. Reed, Frank J. Beurskens, Janine Schuurman, Peter A. Rice, David B. Weiner, Sanjay Ram   +12 more
doaj   +1 more source

The Landscape of Realized Homologous Recombination in Pathogenic Bacteria [PDF]

, 2015
Recombination enhances the adaptive potential of organisms by allowing genetic variants to be tested on multiple genomic backgrounds. Its distribution in the genome can provide insight into the evolutionary forces that underlie traits, such as the ...
Didelot, X, Falush, D, Jolley, KA, Kobayashi, I, Maiden, MCJ, Sheppard, SK, Yahara, K   +6 more
core   +2 more sources

Integrated molecular, phenotypic and epidemiological surveillance of antimicrobial resistance in Neisseria gonorrhoeae in Germany

International Journal of Medical Microbiology
Numbers of infections with Neisseria gonorrhoeae are among the top three sexually transmitted infections (STI) worldwide. In addition, the emergence and spread of antimicrobial resistance (AMR) in Neisseria gonorrhoeae pose an important public-health ...
Kathleen Klaper, Hana Tlapák, Regina Selb, Klaus Jansen, Dagmar Heuer   +4 more
doaj   +1 more source