Results 21 to 30 of about 70,818 (259)

Adaptation to the cervical environment is associated with increased antibiotic susceptibility in Neisseria gonorrhoeae

Nature Communications, 2020
Neisseria gonorrhoeae is an urgent public health threat due to rapidly increasing incidence and antibiotic resistance. In contrast with the trend of increasing resistance, clinical isolates that have reverted to susceptibility regularly appear, prompting
K. C. Ma, T. D. Mortimer, A. Hicks, N. Wheeler, Leonor Sánchez-Busó, D. Golparian, G. Taiaroa, Daniel H. F. Rubin, Yi Wang, D. Williamson, M. Unemo, S. Harris, Y. Grad   +12 more
semanticscholar   +1 more source

Autolysis of Neisseria gonorrhoeae [PDF]

Journal of Bacteriology, 1975
Physiological conditions that would provide maximal rates of autolysis of Neisseria gonorrhoeae were examined. Autolysis was found to occur over a broad pH range with the optimum at pH 9.0 IN 0.05 M tris(hydroxymethyl)amino-methane-maleate buffer. The temperature optimum was found to be 40 C.
F E Young, B H Hebeler
openaire   +3 more sources

Increased power from conditional bacterial genome-wide association identifies macrolide resistance mutations in Neisseria gonorrhoeae

Nature Communications, 2020
The emergence of resistance to azithromycin complicates treatment of Neisseria gonorrhoeae, the etiologic agent of gonorrhea. Substantial azithromycin resistance remains unexplained after accounting for known resistance mutations.
K. C. Ma, T. D. Mortimer, M. A. Duckett, A. Hicks, N. Wheeler, Leonor Sánchez-Busó, Y. Grad   +6 more
semanticscholar   +1 more source

In vitro study of potential antibacterial pometia pinnata leaf extract in Neisseria gonorrhoeae

Medisains, 2021
Background: Gonorrhea cases experiencing antibiotic resistance are increasing due to inadequate treatment or failure to contribute to an increase in antibiotic resistance cases; WHO suggests adding herbal therapy treatment methods is expected to minimize
Gandi Ari Savitri Widayani, Muhammad Choiroel Anwar, Sudirman Sudirman   +2 more
doaj   +1 more source

Investigation of auranofin and gold-containing analogues antibacterial activity against multidrug-resistant Neisseria gonorrhoeae

Scientific Reports, 2020
Neisseria gonorrhoeae represents an urgent public health threat due to the rapid emergence of resistance to current antibiotics and the limited number of anti-gonococcal agents currently in clinical trials.
Ahmed Elkashif, M. Seleem
semanticscholar   +1 more source

Analysis of antimicrobial resistance to 7 antimicrobial agents in 587 strains of Neisseria gonorrhoeae

Pifu-xingbing zhenliaoxue zazhi, 2019
Objective: To investigate the antimicrobial resistance to 7 antimicrobial agents of clinical isolates of Neisseria gonorrhoeae in our hospital from 2016 to 2018.
Ming LI, Yu ZOU, Wen-li HUANG, Yong ZHOU, Wen-ting GUO, Shao-long HUANG   +5 more
doaj   +1 more source

Antimicrobial Resistance of Neisseria gonorrhoeae Isolates from High-Risk Men in Johannesburg, South Africa

Antimicrobial Agents and Chemotherapy, 2020
Neisseria gonorrhoeae antimicrobial drug resistance has emerged worldwide; however, the situation in sub-Saharan Africa is not well documented. We investigated the molecular epidemiology and occurrence of antimicrobial resistance in Neisseria gonorrhoeae
L. Maduna, M. Kock, B. M. van der Veer, O. Radebe, J. McIntyre, L. V. van Alphen, R. Peters   +6 more
semanticscholar   +1 more source

Emergence of ceftriaxone-resistant Neisseria gonorrhoeae strains harbouring a novel mosaic penA gene in China.

Journal of Antimicrobial Chemotherapy, 2020
OBJECTIVES The continuous emergence of ceftriaxone-resistant Neisseria gonorrhoeae strains threatens the effectiveness of current treatment regimens for gonorrhoea.
Leshan Xiu, Qianqin Yuan, Yamei Li, Chi Zhang, Ling-li Tang, Junping Peng   +5 more
semanticscholar   +1 more source

Exfoliating Neisseria gonorrhoeae [PDF]

Nature Reviews Microbiology, 2020
This study finds that Neisseria gonorrhoeae suppresses epithelial exfoliation by nitric oxide-mediated initiation of a host signalling pathway to promote colonization in mice.
openaire   +2 more sources

Resistance of Neisseria Gonorrhoeae to Neutrophils [PDF]

Frontiers in Microbiology, 2011
Infection with the human-specific bacterial pathogen Neisseria gonorrhoeae triggers a potent, local inflammatory response driven by polymorphonuclear leukocytes (neutrophils or PMNs). PMNs are terminally differentiated phagocytic cells that are a vital component of the host innate immune response and are the first responders to bacterial and fungal ...
Alison K. Criss, M. Brittany Johnson
openaire   +3 more sources