Results 21 to 30 of about 67,534 (276)
Gonococcal subcutaneous abscess and pyomyositis: a case report [PDF]
Disseminated gonococcal infection (DGI) is an uncommon complication of Neisseria gonorrhoeae infection, its manifestation varies from a classic arthritis-dermatitis syndrome to uncommon pyogenic infections of several organs.
Boonyasiri, A +4 more
core +2 more sources
Resistance of Neisseria Gonorrhoeae to Neutrophils [PDF]
Infection with the human-specific bacterial pathogen Neisseria gonorrhoeae triggers a potent, local inflammatory response driven by polymorphonuclear leukocytes (neutrophils or PMNs). PMNs are terminally differentiated phagocytic cells that are a vital component of the host innate immune response and are the first responders to bacterial and fungal ...
Alison K. Criss, M. Brittany Johnson
openaire +3 more sources
Development of a SimpleProbe real-Time PCR Assay for rapid detection and identification of the US novel urethrotropic clade of Neisseria meningitidis ST-11 (US_NmUC) [PDF]
Urethritis, or inflammation of the urethra, is one of the most common reasons men seek clinical care. Sexually transmitted pathogens including Neisseria gonorrhoeae are responsible for over half of the symptomatic urethritis cases in U.S. men.
Ermel, Aaron +4 more
core +1 more source
Exfoliating Neisseria gonorrhoeae [PDF]
This study finds that Neisseria gonorrhoeae suppresses epithelial exfoliation by nitric oxide-mediated initiation of a host signalling pathway to promote colonization in mice.
openaire +2 more sources
Eleven primer pairs were developed for the identification of Neisseria gonorrhoeae. The sensitivity and specificity of these primers were evaluated by Real Time (RT)-PCR melt curve analyses with DNA from 145 N. gonorrhoeae isolates and 40 other Neisseria
Sumudu R Perera +9 more
doaj +1 more source
Treatment regimens for gonorrhea have limited efficacy worldwide due to the rapid spread of antimicrobial resistance. Cefixime (CFM) is currently not recommended as a first-line treatment for gonorrhea due to the increasing number of resistant strains ...
Ken Shimuta +4 more
doaj +1 more source
A paperfluidic platform to detect Neisseria gonorrhoeae in clinical samples [PDF]
Globally, the microbe Neisseria gonorrhoeae (NG) causes 106 million newly documented sexually transmitted infections each year. Once appropriately diagnosed, NG infections can be readily treated with antibiotics, but high-risk patients often do not ...
Cabodi, Mario +7 more
core +1 more source
Clinical Validation of Loop‐Mediated Isothermal Amplification Assays for the Rapid Detection of Neisseria gonorrhoeae and Chlamydia trachomatis [PDF]
Neisseria gonorrhoeae and Chlamydia trachomatis are major causes of sexually transmitted infections globally. We developed LAMP assays achieving 96% sensitivity for gonorrhoea and 95% for chlamydia (with extraction), and ≥ 98% specificity. These assays offer a promising diagnostic tool, particularly in high‐burden, resource‐limited settings.
Ahmadi Y +4 more
europepmc +2 more sources
Due to increasing rates of antimicrobial resistance (AMR) in Neisseria gonorrhoeae, alternative treatments should be considered. To assess rifampicin’s potential as a gonorrhea treatment, we used rpoB mutations to estimate rifampicin resistance in ...
Justine Schaeffer +11 more
doaj +1 more source
Damage to mitochondria induces mitophagy, a cellular process that is gaining interest for its therapeutic relevance to a variety of human diseases. However, the mechanism underlying mitochondrial depolarization and clearance in mitophagy remains poorly ...
Tae Woo Kim +11 more
doaj +1 more source

