Results 71 to 80 of about 34,038 (225)

Outer Membrane Vesicles as a Versatile Platform for Vaccine Development: Engineering Strategies, Applications and Challenges

Journal of Extracellular Vesicles, Volume 14, Issue 9, September 2025.
ABSTRACT Outer membrane vesicles (OMVs) are nanosized vesicles naturally secreted by Gram‐negative bacteria and represent a promising platform for vaccine development. OMVs possess inherent immunostimulatory properties due to the presence of pathogen‐associated molecular patterns (PAMPs), providing self‐adjuvanting capabilities and the ability to ...
Asja Garling, Frédéric Auvray, Mathieu Epardaud, Éric Oswald, Priscilla Branchu   +4 more
wiley   +1 more source

A relapse of acute group B streptococcus meningitis in a healthy adult: Case report and review of the literatures

Journal of General and Family Medicine, Volume 26, Issue 5, Page 485-489, September 2025.
Abstract Streptococcus agalactiae (GBS) is a rare cause of meningitis in healthy adults. We report the case of a healthy 33‐year‐old man with acute GBS meningitis who experienced relapsed high‐grade fever and increased intracranial pressure following completing intravenous antibiotics.
Wannisa Wongpipathpong, Pornrujee Hirunpat, Suppachok Kirdlarp, Somnuek Sungkanuparph   +3 more
wiley   +1 more source

Meningococcal arthritis and myopericarditis: a case report

BMC Infectious Diseases, 2017
Background We report the first adult case of Neisseria meningitidis W-135 presenting with meningococcal arthritis and myopericarditis concomitantly, without other classical features of meningococcal disease.
Lloyd Steele, Katie Bechman, Eoghan De Barra, Charles Mackworth-Young   +3 more
doaj   +1 more source

Discovery of RNA‐Targeting Small Molecules: Challenges and Future Directions

MedComm, Volume 6, Issue 9, September 2025.
This review explores challenges and future directions in discovering RNA‐targeting small molecules, from analyzing RNA structures and computational design to experimental workflows. It discusses mechanistic strategies like splicing modulation and RNA degradation, alongside advanced tools (deep learning, docking, and validation) to accelerate drug ...
Zhengguo Cai, Hongli Ma, Fengcan Ye, Dingwei Lei, Zhenfeng Deng, Yongge Li, Ruichu Gu, Han Wen   +7 more
wiley   +1 more source

Intraventricular empyema caused by Neisseria meningitidis

IDCases, 2019
Meningitis is defined as an inflammation of the protective covering of brain and spinal cord collectively called as meninges. Meningeal infection can be complicated by intraventricular empyema.
Divyansh Bajaj, Ankit Agrawal, Darshan Gandhi, Reba Varughese, Sonali Gupta, David Regelmann   +5 more
doaj   +1 more source

Rapid diagnostic testing method to detect ROB β-lactamase gene in Neisseria meningitidis

Molecular and Cellular Probes
blaROB-1 is the only widely found β-lactamase in Neisseria meningitidis, and its presence is on the rise. To enhance our bacterial meningitis testing procedure, we clinically validated a real-time PCR assay to rapidly detect the blaROB gene and predict ...
Andrew Peifer, Anna Kidney, Geetha Nattanmai, Kate Wahl, Sherly Jose, Elizabeth Owuor, Linnell Randall, Erin Klingbeil, Kimberlee A. Musser, Kara Mitchell   +9 more
doaj   +1 more source

Orogenital Transmission of Neisseria meningitidis Causing Acute Urethritis in Men Who Have Sex with Men

Emerging Infectious Diseases, 2019
Neisseria meningitidis sequence type 11 is an emerging cause of urethritis. We demonstrate by using whole-genome sequencing orogenital transmission of a N.
Arnaud Jannic, Hedi Mammeri, Lise Larcher, Vincent Descamps, William Tosini, Bao Phung, Yazdan Yazdanpanah, Fabrice Bouscarat   +7 more
doaj   +1 more source

Neisseria meningitidis cellulitis [PDF]

International Journal of Infectious Diseases, 2012
Elena Casuso-Sáenz, José R. Salcines-Caviedes, Miguel F Carrascosa   +2 more
openaire   +3 more sources

OBSERVATIONS ON A STRAIN OF NEISSERIA MENINGITIDIS IN THE PRESENCE OF GLUCOSE AND MALTOSE [PDF]

, 1951
Charlotte Fitting, Henry W. Scherp
openalex   +1 more source

α-2,3-Sialyltransferase Expression Level Impacts the Kinetics of Lipooligosaccharide Sialylation, Complement Resistance, and the Ability of Neisseria gonorrhoeae to Colonize the Murine Genital Tract

mBio, 2015
Neisseria meningitidis and Neisseria gonorrhoeae modify the terminal lacto-N-neotetraose moiety of their lipooligosaccharide (LOS) with sialic acid. N.
Lisa A. Lewis, Sunita Gulati, Elizabeth Burrowes, Bo Zheng, Sanjay Ram, Peter A. Rice   +5 more
doaj   +1 more source