Results 191 to 200 of about 68,495 (293)

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone   +1 more
wiley   +1 more source

Electrophysiological properties of mesodiencephalic junction neurons projecting to the inferior olive

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Highlights of the main electrophysiological differences between MDJ neurons that project to the IO and those that do not. IO‐projecting neurons fire rebound spikes and are spontaneously active at higher frequencies. The bottom panel shows the anatomical connectivity of the MDJ with both excitatory and newly discovered inhibitory ...
Stijn Voerman   +5 more
wiley   +1 more source

4‐Methylumbelliferone Restores Age‐Related Changes in Perineuronal Nets, Memory, and Neuroinflammation

open access: yesGlia, Volume 74, Issue 12, December 2026.
Brain aging alters perineuronal nets and neuroinflammation. 4‐methylumbelliferone reversed these aging‐associated changes. 4‐methylumbelliferone reduced age‐associated cognitive decline. Six months of chronic oral treatment was well tolerated. ABSTRACT Aging‐associated cognitive decline is closely linked to dysregulated glial activity and chronic ...
Anda Cimpean   +7 more
wiley   +1 more source

Dim light at night impacts circadian rhythms and Alzheimer's disease-like neuroinflammation and neuropathology in humanized APP SAA knock-in mice. [PDF]

open access: yesSleep
Duncan MJ   +15 more
europepmc   +1 more source

2D U‐Net Framework for Multiclass Automated Segmentation of Healthy Structures, Ischemic Stroke, and Glioblastoma in the Rat Brain

open access: yesNMR in Biomedicine, Volume 39, Issue 12, December 2026.
A multitask 2D U‐Net framework enabling automated, accurate segmentation and quantification of rodent brain regions, stroke lesions, and tumors from MRI data. ABSTRACT Rodents are essential for preclinical brain disease research, including stroke, tumors, and neurodegenerative disorders.
Sara Ortega‐Espina   +13 more
wiley   +1 more source

The shared genetic architecture of the TDP‐43 spectrum: Bridging clinical FTLD and neuropathological endophenotypes

open access: yesAlzheimer's &Dementia, Volume 22, Issue 11, November 2026.
Abstract INTRODUCTION TAR DNA‐binding protein 43 (TDP‐43) proteinopathies encompass a spectrum of conditions including frontotemporal lobar degeneration with TDP‐43 inclusions (FTLD‐TDP), limbic‐predominant age‐related TDP‐43 encephalopathy (LATE‐NC), and hippocampal sclerosis (HS).
Maulikkumar Patel   +7 more
wiley   +1 more source

Calretinin and Parvalbumin Trapping of TDP43 and XRCC1 Instructs Neocortical Interneuron Death in Neonatal Hypoxic-Ischemic Encephalopathy. [PDF]

open access: yesBiomolecules
Martin LJ   +9 more
europepmc   +1 more source

Accelerated Brain Atrophy in Epilepsy: A Prospective Population‐Based Study

open access: yesAnnals of Neurology, Volume 100, Issue 5, Page 1028-1038, November 2026.
Objective Previous longitudinal neuroimaging studies suggest that epilepsy is a progressive disorder. To date, these findings have relied largely on populations from tertiary centers, resulting in ascertainment bias, as severely affected individuals are more likely to be rescanned.
Marian Galovic   +6 more
wiley   +1 more source

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