Results 211 to 220 of about 68,495 (293)

Advances in the Comprehensive Tree Shrew Brain Atlas. [PDF]

Biomolecules
Ma W, Zhang J, Liao H, Wang T.
europepmc   +1 more source

Individual Differences in Sleep Quality: Exploring the Impact of Temperament on Sleep Through Anxiety and Depression

Personality and Mental Health, Volume 20, Issue 4, November 2026.
ABSTRACT According to the functional ensemble of temperament (FET) model, individual differences in temperament arise from the balance of neurotransmitter systems also crucial for regulating circadian rhythms and sleep, suggesting a strong neurobiological link between temperament and sleep behavior.
Stefano Lasaponara, Angelica Scuderi, Elisa Pellegrini, Ludovica Annarumma, Valentina Piga, Sara Lo Presti, Maurizio Gorgoni   +6 more
wiley   +1 more source

How does the cerebellum contribute to cognitive functions? [PDF]

PLoS Biol
Diedrichsen J, McDougle SD.
europepmc   +1 more source

Histone Modifications at the Intersection of Aging, Neuroinflammation and Metabolism in Alzheimer's Disease

Aging Cell, Volume 25, Issue 11, November 2026.
This review examines how histone modifications integrate aging, metabolic dysfunction and neuroinflammation to shape persistent, cell‐type‐specific chromatin states in Alzheimer's disease. By distinguishing causal regulation from association through perturbation, persistence and reversibility, it highlights metabolic–epigenetic feedback loops and ...
Junyi Liang, Huawen Cao, Xiumin Ren, Nan Sha, Xueqing Han, Ling Jiang, Bin Liu, Weiming Zhao   +7 more
wiley   +1 more source

Editorial: Grey matters in the lab: utilizing human brain tissue for basic research, disease modeling and drug development. [PDF]

Front Synaptic Neurosci
Szegedi V, Yang D, Feldmeyer D, Lamsa K.
europepmc   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, Volume 36, Issue 6, November 2026.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Beneath the Spike: Laminar Microcircuits of Human Interictal Epileptiform Discharges. [PDF]

Epilepsy Curr
Rolston JD.
europepmc   +1 more source

Data‐driven thresholds for standardized classification of severe Alzheimer's disease neuropathology using digital neuropathology

Brain Pathology, Volume 36, Issue 6, November 2026.
We generated digital pathologic algorithms (AI‐based modules that can be freely shared) to: optimize the sampling (ROI) for diagnosis of ADNC‐related tau pathology; compare/transition between Aperio and HALO platforms; and rationalize severe Braak NFT staging, so that all Braak‐VI cases had dementia, and all Braak‐V cases had MCI or dementia.
Ryan K. Shahidehpour, Allison M. Neltner, Mitchell A. Klusty, Cole Corbett, Angelique D. Gonzalez, David A. Gutman, David W. Fardo, Adam D. Bachstetter, Cody Bumgardner, Margaret E. Flanagan, Peter T. Nelson   +10 more
wiley   +1 more source

Chorea-athetosis-like hyperkinetic seizures in temporal lobe epilepsy: insights from stereo-EEG in three patients. [PDF]

Epilepsy Behav Rep
Zhuang J, Fei L, Li H, Li K, Tan Q, Li S, Guo Q, Cai M.   +7 more
europepmc   +1 more source

Nature, nurture, and 5‐HT4R: Familial predisposition, not parental bonding, is associated with brain 5‐HT4R in a sex‐specific manner

Psychiatry and Clinical Neurosciences, Volume 80, Issue 11, Page 898-904, November 2026.
Background Major depressive disorder (MDD) aggregates in families. The neostriatum, key to reward and attachment circuits, has the highest density of serotonin 4 receptors (5‐HT4R). Striatal 5‐HT4R is low in MDD and linked to familial depression risk. Poor parental bonding increases depression risk, yet whether nature and nurture converge on 5‐HT4R is ...
Randi T. Kjær, Martin B. Jørgensen, Kristian H. R. Jensen   +2 more
wiley   +1 more source