Results 71 to 80 of about 115,708 (268)
Empiricism without Magic: Transformational Abstraction in Deep Convolutional Neural Networks [PDF]
, 2018 In artificial intelligence, recent research has demonstrated the remarkable potential of Deep Convolutional Neural Networks (DCNNs), which seem to exceed state-of-the-art performance in new domains weekly, especially on the sorts of very difficult ...
Buckner, Cameron
core +1 more source
Glutamatergic Inhibition in Sensory Neocortex [PDF]
Cerebral Cortex, 2009 In the mammalian brain, glutamate and gamma-aminobutyric acid are considered major excitatory and inhibitory neurotransmitters, respectively. However, we have found evidence that glutamate can also act as a postsynaptic inhibitory neurotransmitter in layer 4 of the neocortex.
Charles C, Lee, S Murray, Sherman
openaire +2 more sources
Nanoporous Microelectrodes for Neural Electrophysiology Recordings in Organotypic Culture
Advanced Materials Technologies, EarlyView.The highly porous microelectrodes have been designed and printed on culture membranes, allowing to record electrophysiological neural activity for rodent brain slices. To keep the biocompatible nanoporous structure, the microelectrodes and insulative layer are fabricated on the bottom of culture membranes with only small connector pads added on the top.
Petro Lutsyk +3 more
wiley +1 more source
eLife, 2017 Neocortical basal radial glia (bRG) and cerebellar Bergmann glia (BG) are basal progenitors derived from ventricular apical radial glia (aRG) that selectively lose their apical processes.
Xin Heng +3 more
doaj +1 more source
Quantitative relationships in delphinid neocortex [PDF]
Frontiers in Neuroanatomy, 2014 Possessing large brains and complex behavioral patterns, cetaceans are believed to be highly intelligent. Their brains, which are the largest in the Animal Kingdom and have enormous gyrification compared with terrestrial mammals, have long been of scientific interest. Few studies, however, report total number of brain cells in cetaceans, and even fewer
Heidi S Mortensen +7 more
openaire +4 more sources
Advanced Science, EarlyView.Astrocytic TIA1‐mediated stress granules (SGs) promote demyelination by sequestering the mRNA of cholesterol synthesis genes. In this model, astrocytic TIA1‐mediated SGs were increased in the optic nerves of EAE mice, leading to the downregulation of cholesterol synthesis genes such as HMGCS1 through sequestration of their mRNA into SGs, which ...
Zheyu Fang +11 more
wiley +1 more source
Quantum calcium-ion interactions with EEG
, 2019 Previous papers have developed a statistical mechanics of neocortical interactions (SMNI) fit to short-term memory and EEG data. Adaptive Simulated Annealing (ASA) has been developed to perform fits to such nonlinear stochastic systems.
Asher +29 more
core +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson +1 more
wiley +1 more source
Towards deep learning with segregated dendrites
eLife, 2017 Deep learning has led to significant advances in artificial intelligence, in part, by adopting strategies motivated by neurophysiology. However, it is unclear whether deep learning could occur in the real brain.
Jordan Guerguiev +2 more
doaj +1 more source
The Clinical Spectrum and Neurodevelopmental Pathogenesis of KPTN‐Related Disorder in a Mouse Model
Annals of Neurology, EarlyView.Objective Pathogenic variants in Kaptin (KPTN) cause KPTN‐related disorder (KRD). KPTN modulates mTOR signaling activation within the KICSTOR complex in response to cellular amino acid levels. We define the clinical spectrum and investigate the developmental pathogenesis of KRD.
Lettie E. Rawlins +104 more
wiley +1 more source